The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Chemoprevention of cancer
Abstract
In this short article, we review the conceptual basis for chemoprevention of cancer, the proven clinical efficacy of this concept, and current trends to develop new chemopreventive agents based on understanding of their mechanisms of action. Four classes of new agents, namely selective inhibitors of cyclooxygenase-2, selective estrogen receptor modulators, rexinoids (retinoids that bind selectively to the receptors known as RXRs) and ligands for the peroxisome proliferator-activated receptor-gamma are discussed in detail. The importance of developing totally new classes of chemopreventive agents is stressed, with particular emphasis on the potential usefulness of new synthetic triterpenoids derived from naturally occurring molecules.
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Citations
Cites
The nuclear receptor superfamily: the second decade
Mangelsdorf, D. J., Thummel, C., Beato, M., Herrlich, P., Schütz, G., Umesono, K., Blumberg, B., Kastner, P., Mark, M., Chambon, P., et al. (1995) · Cell · doi:10.1016/0092-8674(95)90199-x · Cited by 6,964
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Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease
Omenn, G. S., Goodman, G. E., Thornquist, M. D., Balmes, J., Cullen, M. R., Glass, A., Keogh, J. P., Meyskens, F. L., Valanis, B., Williams, J. H., et al. (1996) · New England Journal of Medicine · doi:10.1056/nejm199605023341802 · Cited by 3,638
Cited by
Bissell, M. J., & Radisky, D. (2001) · Nature Reviews Cancer · doi:10.1038/35094059 · Cited by 2,180
Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer.
Yadav, V. R., Prasad, S., Sung, B., Kannappan, R., & Aggarwal, B. B. (2010) · Toxins · doi:10.3390/toxins2102428 · Cited by 320
Kapadia, G. J., Azuine, M. A., Sridhar, R., Okuda, Y., Tsuruta, A., Ichiishi, E., Mukainake, T., Takasaki, M., Konoshima, T., Nishino, H., et al. (2003) · Pharmacological Research · doi:10.1016/s1043-6618(02)00285-2 · Cited by 186
J. Kapadia, G., A. Azuine, M., Subba Rao, G., Arai, T., Iida, A., & Tokuda, H. (2011) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/187152011795347504 · Cited by 135
Kim, H., Kim, H., Mosaddik, A., Gyawali, R., Ahn, K. S., & Cho, S. K. (2012) · Food Chemistry · doi:10.1016/j.foodchem.2012.01.053 · Cited by 87
Metadata
- Authors
- Sporn, M. B., & Suh, N.
- Venue
- Carcinogenesis
- Publisher
- Oxford University Press (OUP)
- Published
- 2000-03
- Volume
- 21
- Issue
- 3
- Pages
- 525-530
- ISSN
- 0143-3334 (ISSN-L)
- 1460-2180
- OpenAlex
- W2117900168
- Cited by
- 439
- References
- 3
- FWCI
- 15.69
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
