The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Parvalbumin Expression in Visual Cortical Interneurons Depends on Neuronal Activity and TrkB Ligands during an Early Period of Postnatal Development
Abstract
The differentiation of cortical interneurons is controlled by environmental factors. Here, we describe the role of activity and neurotrophins in regulating parvalbumin (PARV) expression using organotypic cultures (OTC) of rat visual cortex as model system. In OTC, PARV expression was dramatically delayed. The organotypic proportion of approximately 6% PARV neurons was not established before 50-70 DIV, whereas in vivo all neurons are present until P20. Thalamic afferents increased cortical PARV mRNA in OTC, but not to the age-matched in vivo level. During the first 10 DIV, BDNF and NT-4 accelerated PARV mRNA expression in a Trk receptor and MEK2 dependent manner. The BDNF action required PI3 kinase signalling. PARV expression required activity. The proportion of neurons which managed to up-regulate PARV was inversely related to the duration of early transient periods of activity deprivation. Long-term activity-deprived OTC completely failed to up-regulate PARV mRNA. Both TrkB ligands failed to promote PARV expression in activity-deprived OTC. However, a few basket and chandelier neurons were observed, suggesting that the development of class-specific morphological features is activity-independent. Once established, PARV expression became resistant to late-onset activity deprivation. In conclusion, PARV expression depended on activity and TrkB ligands which appear to prime the PARV expression already before its developmental onset.
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Zhang, Z. J., & Reynolds, G. P. (2002) · Schizophrenia Research · doi:10.1016/s0920-9964(01)00188-8 · Cited by 460
The absence of a major Ca 2+ signaling pathway in GABAergic neurons of the hippocampus
Sík, A., Hájos, N., Gulácsi, A., Mody, I., & Freund, T. F. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.6.3245 · Cited by 186
Alc�ntara, S., Ferrer, I., & Soriano, E. (1993) · Anatomy and Embryology · doi:10.1007/bf00191452 · Cited by 174
Cited by
Hashimoto, T., Arion, D., Unger, T., Maldonado-Avilés, J. G., Morris, H. M., Volk, D. W., Mirnics, K., & Lewis, D. A. (2008) · Molecular Psychiatry · doi:10.1038/sj.mp.4002011 · Cited by 490
Gonchar, Y. (2008) · Frontiers in Neuroanatomy · doi:10.3389/neuro.05.003.2007 · Cited by 369
“…of progenitors in the MGE, which after migration to cortex as postmitotic neurons differentiate into fast spiking cells with basket and chandelier morphologies (Anderson et al., 2001; Butt et al., 2005; Klostermann and Wahle, 1999; Patz et al., 2004; Wichterle et al., 2001; Xu et al., 2004).”
BackgroundResultNeurobiology of premature brain injury
Salmaso, N., Jablonska, B., Scafidi, J., Vaccarino, F. M., & Gallo, V. (2014) · Nature Neuroscience · doi:10.1038/nn.3604 · Cited by 268
Steullet, P., Cabungcal, J. H., Monin, A., Dwir, D., O'Donnell, P., Cuenod, M., & Do, K. Q. (2016) · Schizophrenia Research · doi:10.1016/j.schres.2014.06.021 · Cited by 262
Postnatal phenotype and localization of spinal cord V1 derived interneurons
Alvarez, F. J., Jonas, P. C., Sapir, T., Hartley, R., Berrocal, M. C., Geiman, E. J., Todd, A. J., & Goulding, M. (2005) · Journal of Comparative Neurology · doi:10.1002/cne.20711 · Cited by 243
Metadata
- Authors
- Patz, S.
- Venue
- Cerebral Cortex
- Publisher
- Oxford University Press (OUP)
- Published
- 2004-03-01
- Volume
- 14
- Issue
- 3
- Pages
- 342-351
- ISSN
- 1047-3211 (ISSN-L)
- 1460-2199
- OpenAlex
- W2099314926
- Cited by
- 170
- References
- 3
- FWCI
- 1.56
- Type
- journal article
- Language
- en
- Open access
- closed
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