False-negative Results of Human Immunodeficiency Virus (HIV) Rapid Testing in HIV Controllers
Open accessAbstract
Serological assays were performed on 85 human immunodeficiency virus-controller samples . 6% presented a negative rapid screening test 7% presented an indeterminate Western blot. The enzyme immunoassay ratio decreased in controllers who had continual negative ultrasensitive HIV RNA results since inclusion.
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False test results occur in POCT due to intentional or unintentional misuse of the test, equipment failure or poor testing and result management processes.
“Although POCT are designed to be simple and robust, false test results occur [67], due to intentional or unintentional misuse of the test, equipment failure or poor testing and result management processes.”
From Point-of-care testing: state-of-the art and perspectives (2025) · cites this paper as [67]
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Point-of-care testing: state-of-the art and perspectives
Plebani, M., Nichols, J. H., Luppa, P. B., Greene, D., Sciacovelli, L., Shaw, J., Khan, A. I., Carraro, P., Freckmann, G., Dimech, W., et al. (2025) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2024-0675 · Cited by 119 · see citing works
- Authors
- Hage-Sleiman, M., Tremeaux, P., Fillion, M., Boufassa, F., Melard, A., Gardiennet, E., Mariaggi, A.-A., Plantier, J.-C., Rouzioux, C., Lambotte, O., Avettand-Fenoel, V., for the CODEX ANRS Cohort Study Group, Faller, J.-P., Roblot, P., Plainchamp, M. D., Aumaître, H., Malet, M., Rouger, C., Rémy, G., Isabelle, M. K., Delassus, J.-L., Devidas, A., Froguel, E., Tassi, S., Genet, P., Gerbe, J., Patey, O., Laurent, R., Drobacheff, M.-C., Proust, A., Gil, H., Gérard, L., Oksenhendler, E., Lucht, F., Ronat, V., Dupon, M., Dutronc, H., Le Puil, S., Schmit, J.-L., Decaux, N., Molina, J.-M., Lascoux, C., Parlier, S., Jean-Pierre, B. R. U., Clavere, G., Lambotte, O., Delfraissy, J.-F., Goujard, C., Bourdic, K., Bergmann, J.-F., Parrinello, M., Pichancourt, G., Welker, Y., Lafeuillade, A., Gisèle, P., Rapp, C., Lerondel, M., de Truchis, P., Berthe, H., Jeantils, V., Mchangama, F., Vittecoq, D., Bolliot, C., Consigny, P. H., Touam, F., Pialoux, G., le Nagat, S., Bouchaud, O., Honoré, P., Boué, F., Raho-Moussa, M., Weiss, L., Collias, L., Salmon-Céron, D., Pietri, M.-P., Zucman, D., Blétry, O., Bornarel, D., Mortier, E., Feng, Z., Lelièvre, J.-D., Katlama, C., Dudoit, Y., Simon, A., Lupin, C., Girard, P.-M., Pauchard, M., Abel, S., Cabié, A., Fialaire, P., Chennebault, J.-M., Rehaiem, M. S., Martin, L. D. S., Perfezou, P., Duthe, M. J.-C., Morlat, P., Caldato, S., Neau, D., LE Puil, S., Weinbreck, P., Genet, C., Makhloufi, D., GARNIER, F., Poizot-Martin, I., Fauche, O., Ivanova, A., Yeni, P., Matheron, S., Cyndi, G., Raffi, F., Hervé Hüe, M., Perré, P., Roger, P. M., Joulie, A., Rosenthal, É., Michelet, C., Souala, F., Ratajczak, M., Partisani, M., Fischer, P., Bernard, L., Nau, P., Marchou, B., Balsarin, F., Verdon, R., Feret, P., Jacomet, C., Piroth, L., Gohier, S., Leclercq, P., Meybeck, A., Biekre, R., May, T., Caron, F., Debab, Y., Theron, M. D., Miailhes, P., Ogoudjobi, M. S., Mercié, P., Gatfosse, M., Martinot, M., Pachart, A., Poubeau, P., Uludag, A., Arsac, P., Bouaraba, L., Szmania, I. D. L., Richier, M. L., Daneluzzi, V., Rouveix, E., Beck-Wirth, G., Romand, P., Blum, L., Deschaud, M., Michau, C., Bernard, C., Salaun, F., Muller, P., Poinsignon, Y., Lepretre, A., Deschaud, M., Lambert, T., Hocqueloux, L., de Dieulevault, B., Philibert, P., Sow, M. P., Sotto, A., Viard, J.-P., Cros, A., De Lavaissiere, M., Duthe, M. J. C., Gaud, C., Niault, M. A., Mouton-Rioux, V., Talarmin, J., Duthé, M. J. C., Mathilde, D., Natur, M. S., Hitoto, H., & Ibrahim, M. A. M.
- Affiliations
- Hôpital Necker-Enfants Malades (FR)
- Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, Paris, France
- Centre National de la Recherche Scientifique (FR)
- Université Paris-Sud (FR)
- Hôpital Charles-Nicolle (FR)
- Sorbonne Paris Cité (FR)
- AP-HP, Laboratoire de Microbiologie Clinique, Hôpital Necker-Enfants Malades, Paris, France
- ORCID
- Boufassa, Faroudy
- Gardiennet, Elise
- Mariaggi, Alice-Andrée
- Plantier, Jean-Christophe
- Avettand-Fenoel, Véronique
- Roblot, Pascal
- Aumaître, Hugues
- Genet, Philippe
- Gil, Helder
- Gérard, Laurence
- Molina, Jean-Michel
- Goujard, Cécile
- Bourdic, Katia
- Bergmann, Jean-François
- Rapp, Christophe
- Jeantils, Vincent
- Consigny, Paul Henri
- Bouchaud, Olivier
- Weiss, Laurence
- Zucman, David
- Mortier, Emmanuel
- Lelièvre, Jean-Daniel
- Katlama, Christine
- Girard, Pierre-Marie
- Abel, Sylvie
- Martin, Luc de Saint
- Ivanova, Alena
- Matheron, Sophie
- Fischer, Patricia
- Bernard, Louis
- Marchou, Bruno
- Verdon, Renaud
- Jacomet, Christine
- Piroth, Lionel
- Caron, François
- Miailhes, Patrick
- Mercié, Patrick
- Martinot, Martin
- Pachart, Anne
- Poubeau, Patrice
- Blum, Laurent
- Michau, Christophe
- Hocqueloux, Laurent
- Sotto, Albert
- Viard, Jean-Paul
- Talarmin, Jean–Philippe
- Hitoto, Hikombo
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2019-09-21
- Volume
- 70
- Issue
- 8
- Pages
- 1754-1757
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2973905488
- Cited by
- 2
- References
- 0
- Citations by year
- 2024: 1 · 2021: 1
- FWCI
- 0.14
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
- Locations
- Clinical Infectious Diseases (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Funders
- ANRS
- Topics
- Life Sciences › Immunology and Microbiology › Virology › HIV Research and Treatment
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Health Sciences › Medicine › Physiology › Clinical Laboratory Practices and Quality Control
- Keywords
- HIV controllers, rapid HIV testing, false-negative results, HIV serology, HIV screening
- MeSH terms
- Negative Results, Enzyme-Linked Immunosorbent Assay, HIV, Humans, Immunoenzyme Techniques, Blotting, Western, HIV Antibodies, HIV-2, HIV Infections
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