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Volatile organic compounds in exhaled air from patients with lung cancer.

Gordon, S M, Szidon, J P, Krotoszynski, B K, Gibbons, R D, O'Neill, H J·1985·Clinical Chemistry

Abstract

Using a specially developed breath collection technique and computer-assisted gas chromatography/mass spectrometry (GC/MS), we have identified in the exhaled air of lung cancer patients several volatile organic compounds that appear to be associated with the disease. The GC/MS profiles of 12 samples from lung cancer patients and 17 control samples were analyzed by using general computerized statistical procedures to distinguish lung cancer patients from controls. The selected volatile compounds had sufficient diagnostic power in the GC/MS profiles to allow almost complete differentiation between the two groups in a limited patient population.

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Metadata

Authors
Gordon, S. M., Szidon, J. P., Krotoszynski, B. K., Gibbons, R. D., & O'Neill, H. J.
Venue
Clinical Chemistry
Published
1985-08-01
Volume
31
Issue
8
Pages
1278-1282
ISSN
  • 0009-9147 (ISSN-L)
  • 1530-8561
OpenAlex
W1892693836
Cited by
366
References
0
FWCI
2.12
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Volatile organic compounds in exhaled air from patients with lung cancer. https://app.cochat.ai/papers/10.1093/clinchem/31.8.1278
The paper
Gordon, S. M., Szidon, J. P., Krotoszynski, B. K., Gibbons, R. D., & O'Neill, H. J. (1985). Volatile organic compounds in exhaled air from patients with lung cancer. Clinical Chemistry. https://doi.org/10.1093/clinchem/31.8.1278

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.