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Metabolism of anabolic androgenic steroids

Schänzer, W·1996·Clinical Chemistry

Abstract

Anabolic androgenic steroids (AAS) are misused to a high extent in sports by athletes to improve their physical performance. Sports federations consider the use of these drugs in sports as doping. The misuse of AAS is controlled by detection of the parent AAS (when excreted into urine) and (or) their metabolites in urine of athletes. I present a review of the metabolism of AAS. Testosterone is the principal androgenic steroid and its metabolism is compared with that of AAS. The review is divided into two parts: the general metabolism of AAS, which is separated into phase I and phase II metabolism and includes a systematic discussion of metabolic changes in the steroid molecule according to the regions (A-D rings), and the specific metabolism of AAS, which presents the metabolism of 26 AAS in humans.

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Metadata

Authors
Schänzer, W.
Venue
Clinical Chemistry
Published
1996-07-01
Volume
42
Issue
7
Pages
1001-1020
ISSN
  • 0009-9147 (ISSN-L)
  • 1530-8561
OpenAlex
W2160243831
Cited by
372
References
0
FWCI
34.39
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Metabolism of anabolic androgenic steroids. https://app.cochat.ai/papers/10.1093/clinchem/42.7.1001
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Schänzer, W. (1996). Metabolism of anabolic androgenic steroids. Clinical Chemistry. https://doi.org/10.1093/clinchem/42.7.1001

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.