The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Epidemiology of Blastomycosis in a Region of High Endemicity in North Central Wisconsin
Abstract
The clinical and epidemiologic features of 73 patients with laboratory-confirmed blastomycosis who were identified over an 11-year period in North Central Wisconsin are presented. Pulmonary disease was the sole manifestation in 77% of patients. More than one-half of all patients had symptoms that included fever, cough, weight loss, night sweats, and pleuritic chest pain. Virtually all were previously healthy, and most did not have an outdoor occupation. However, 82% of these patients lived or had visited within 500 m of rivers or associated waterways. The majority experienced the onset of symptoms between December and April. The estimated mean annual incidence rate of infection for Vilas County was 40.4 cases per 100,000 persons, and that for the largest city in the county was 101.3 cases per 100,000 persons. Several areas with an exceptionally high incidence of the infection were observed. We suggest that, in regions where blastomycosis is hyperendemic, clinical disease is most often pulmonary and occurs in immunocompetent individuals and that residence near an ecological focus may be a greater risk factor for acquisition of blastomycosis than is occupation.
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“Endemicity is most pronounced in the hyperendemic regions of north central Wisconsin where the disease incidence can exceed 100 cases per 100,000 inhabitants [175].”
From Race and ethnicity: Risk factors for fungal infections? (2023) · cites this paper as [175]
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Metadata
- Authors
- Baumgardner, D. J., Buggy, B. P., Mattson, B. J., Burdick, J. S., & Ludwig, D.
- Affiliations
- University of Wisconsin–Madison (US)
- Corresponding author
- Baumgardner, D. J.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1992-10-01
- Volume
- 15
- Issue
- 4
- Pages
- 629-635
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2016271968
- Cited by
- 131
- References
- 23
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 6 · 2023: 4 · 2022: 2 · 2021: 1 · 2020: 10 · 2019: 7 · 2018: 4 · 2017: 5 · 2016: 2 · 2015: 11 · 2014: 6 · 2013: 2 · 2012: 4
- FWCI
- 0.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Infectious Diseases (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ulster University
- Topics
- Health Sciences › Medicine › Infectious Diseases › Fungal Infections and Studies
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Microbiology (medical) › Actinomycetales infections and treatment
- Keywords
- blastomycosis, epidemiology, pulmonary blastomycosis, hyperendemicity, incidence, risk factors, river proximity, seasonal onset, immunocompetent patient, Vilas County, Wisconsin, clinical features
- MeSH terms
- Adolescent, Adult, Blastomycosis, Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Lung Diseases, Fungal, Male, Middle Aged, Residence Characteristics, Risk Factors, Wisconsin, Incidence
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