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Cited by 468

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Evaluation of New Anti-Infective Drugs for the Treatment of Urinary Tract Infection

Open access
Rubin, Robert H., Shapiro, Eugene D., Andriole, Vincent T., Davis, Robert J., Stamm, Walter E.·1992·Clinical Infectious Diseases

Abstract

The term urinary tract infection (UTI) encompasses a broad range of clinical entities that share one characteristic: a positive urine culture. Clinical manifestations and responses to therapy are diverse even when comparable numbers of a particular bacterial species are identified on urine culture. These guidelines include discussion of acute uncomplicated cystitis, acute uncomplicated pyelonephritis, and complicated infections of the urinary tract. It is proposed that the finding of > or = 10(3) cfu/mL of urine defines significant bacteriuria in acute uncomplicated cystitis, > or = 10(4) cfu/mL in acute uncomplicated pyelonephritis and UTI in men, and > or = 10(5) cfu/mL in complicated UTI. The preferred clinical study design is prospective, randomized, and controlled with an active agent. Ideally, treatment with antimicrobial agents should eradicate the infecting organism, bring about the resolution of clinical signs and symptoms, have few adverse effects, and prevent reinfection.

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Crossref · 10.1093/clind/15.supplement_1.s216

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Metadata

Authors
Rubin, R. H., Shapiro, E. D., Andriole, V. T., Davis, R. J., & Stamm, W. E.
Venue
Clinical Infectious Diseases
Published
1992-11-01
Volume
15
Issue
Supplement_1
Pages
S216-S227
ISSN
  • 1058-4838 (ISSN-L)
  • 1537-6591
OpenAlex
W2007708769
Cited by
468
References
2
FWCI
9.06
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Evaluation of New Anti-Infective Drugs for the Treatment of Urinary Tract Infection. https://app.cochat.ai/papers/10.1093/clind/15.supplement_1.s216
The paper
Rubin, R. H., Shapiro, E. D., Andriole, V. T., Davis, R. J., & Stamm, W. E. (1992). Evaluation of New Anti-Infective Drugs for the Treatment of Urinary Tract Infection. Clinical Infectious Diseases. https://doi.org/10.1093/clind/15.supplement_1.s216

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.