CoChat
Sign Up
Cited by 102

The DOI matches its Crossref record.

Structural basis for SH3 domain‐mediated high‐affinity binding between Mona/Gads and SLP‐76

Harkiolaki, Maria, Lewitzky, Marc, Gilbert, Robert J.C., Jones, EYvonne, Bourette, Roland P., Mouchiroud, Guy, Sondermann, Holger, Moarefi, Ismail, Feller, Stephan M.·2003·The EMBO Journal
DOI 10.1093/emboj/cdg258
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1093/emboj/cdg258

Cites

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

No references could be resolved yet.

Research works printed but not linked: 76

  1. Altamirano MM et al. (2001) Ligand‐independent assembly of recombinant human CD1 by using oxidative refolding chromatography. Proc Natl Acad Sci USA, 98, 3288–3293. · DOI
  2. Asada H et al. (1999) Grf40, a novel Grb2 family member, is involved in T cell signaling through interaction with SLP‐76 and LAT. J Exp Med, 189, 1383–1390. · DOI
  3. Barnett P, Bottger G, Klein AT, Tabak HF and Distel B (2000) The peroxisomal membrane protein Pex13p shows a novel mode of SH3 interaction. EMBO J, 19, 6382–6391. · DOI
  4. Berry DM, Nash P, Liu SK, Pawson T and McGlade CJ (2002) A high‐affinity Arg–X–X–Lys SH3 binding motif confers specificity for the interaction between Gads and SLP‐76 in T cell signaling. Curr Biol, 12, 1336–1341. · DOI · Paper page
  5. Bork P, Schultz J and Ponting CP (1997) Cytoplasmic signalling domains: the next generation. Trends Biochem Sci, 22, 296–298. · DOI
  6. Bourette RP, Arnaud S, Myles GM, Blanchet JP, Rohrschneider LR and Mouchiroud G (1998) Mona, a novel hematopoietic‐specific adaptor interacting with the macrophage colony‐stimulating factor receptor, is implicated in monocyte/macrophage development. EMBO J, 17, 7273–7281. · DOI
  7. Bourgin C, Bourette RP, Arnaud S, Liu Y, Rohrschneider LR and Mouchiroud G (2002) Induced expression and association of the Mona/Gads adapter and Gab3 scaffolding protein during monocyte/macrophage differentiation. Mol Cell Biol, 22, 3744–3756. · DOI
  8. Brunger AT et al. (1998) Crystallography and NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr D, 54, 905–921. · DOI
  9. Burack WR, Cheng AM and Shaw AS (2002) Scaffolds, adaptors and linkers of TCR signaling: theory and practice. Curr Opin Immunol, 14, 312–316. · DOI
  10. Cestra G, Castagnoli L, Dente L, Minenkova O, Petrelli A, Migone N, Hoffmuller U, Schneider‐Mergener J and Cesareni G (1999) The SH3 domains of endophilin and amphiphysin bind to the proline‐rich region of synaptojanin 1 at distinct sites that display an unconventional binding specificity. J Biol Chem, 274, 32001–32007. · DOI
  11. Choi YB, Kim CK and Yun Y (1999) Lad, an adapter protein interacting with the SH2 domain of p56lck, is required for T cell activation. J Immunol, 163, 5242–5249. · DOI
  12. Corpet F (1988) Multiple sequence alignment with hierarchical clustering. Nucleic Acids Res, 16, 10881–10890. · DOI
  13. Delbruck H, Ziegelin G, Lanka E and Heinemann U (2002) An Src homology 3‐like domain is responsible for dimerization of the repressor protein KorB encoded by the promiscuous IncP plasmid RP4. J Biol Chem, 277, 4191–4198. · DOI
  14. Ellis JH, Ashman C, Burden MN, Kilpatrick KE, Morse MA and Hamblin PA (2000) GRID: a novel Grb‐2‐related adapter protein that interacts with the activated T cell costimulatory receptor CD28. J Immunol, 164, 5805–5814. · DOI
  15. Esnouf RM (1997) An extensively modified version of MolScript that includes greatly enhanced coloring capabilities. J Mol Graph Model, 15, 132–134, 112–133. · DOI
  16. Esnouf RM (1999) Further additions to MolScript version 1.4, including reading and contouring of electron‐density maps. Acta Crystallogr D, 55, 938–940. · DOI
  17. Feller SM, Wecklein H, Lewitzky M, Kibler E and Raabe T (2002) SH3 domain‐mediated binding of the Drk protein to Dos is an important step in signaling of Drosophila receptor tyrosine kinases. Mech Dev, 116, 129–139. · DOI
  18. Ghose R, Shekhtman A, Goger MJ, Ji H and Cowburn D (2001) A novel, specific interaction involving the Csk SH3 domain and its natural ligand. Nat Struct Biol, 8, 998–1004. · DOI
  19. Gouet P, Courcelle E, Stuart DI and Metoz F (1999) ESPript: analysis of multiple sequence alignments in PostScript. Bioinformatics, 15, 305–308. · DOI
  20. Guijarro JI, Sunde M, Jones JA, Campbell ID and Dobson CM (1998) Amyloid fibril formation by an SH3 domain. Proc Natl Acad Sci USA, 95, 4224–4228. · DOI
  21. Holm L and Sander C (1994) Searching protein structure databases has come of age. Proteins, 19, 165–173. · DOI
  22. Ikemizu S, Gilbert RJ, Fennelly JA, Collins AV, Harlos K, Jones EY, Stuart DI and Davis SJ (2000) Structure and dimerization of a soluble form of B7‐1. Immunity, 12, 51–60. · DOI
  23. Jackman JK, Motto DG, Sun Q, Tanemoto M, Turck CW, Peltz GA, Koretzky GA and Findell PR (1995) Molecular cloning of SLP‐76, a 76‐kDa tyrosine phosphoprotein associated with Grb2 in T cells. J Biol Chem, 270, 7029–7032. · DOI
  24. Jones TA, Zou JY, Cowan SW and Kjeldgaard (1991) Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr A, 47, 110–119. · DOI
  25. Kabsch W and Sander C (1983) Dictionary of protein secondary structure: pattern recognition of hydrogen‐bonded and geometrical features. Biopolymers, 22, 2577–2637. · DOI · Paper page
  26. Kami K, Takeya R, Sumimoto H and Kohda D (2002) Diverse recognition of non‐PxxP peptide ligands by the SH3 domains from p67(phox), Grb2 and Pex13p. EMBO J, 21, 4268–4276. · DOI
  27. Kang H, Freund C, Duke‐Cohan JS, Musacchio A, Wagner G and Rudd CE (2000) SH3 domain recognition of a proline‐independent tyrosine‐based RKxxYxxY motif in immune cell adaptor SKAP55. EMBO J, 19, 2889–2899. · DOI
  28. Kato M, Miyazawa K and Kitamura N (2000) A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs‐binding protein via a novel binding motif PX(V/I)(D/N)RXXKP. J Biol Chem, 275, 37481–37487. · DOI · Paper page
  29. Kay BK, Williamson MP and Sudol M (2000) The importance of being proline: the interaction of proline‐rich motifs in signaling proteins with their cognate domains. FASEB J, 14, 231–241. · DOI
  30. Kishan KV, Scita G, Wong WT, Di Fiore PP and Newcomer ME (1997) The SH3 domain of Eps8 exists as a novel intertwined dimer. Nat Struct Biol, 4, 739–743. · DOI
  31. Kishan KV, Newcomer ME, Rhodes TH and Guilliot SD (2001) Effect of pH and salt bridges on structural assembly: molecular structures of the monomer and intertwined dimer of the Eps8 SH3 domain. Protein Sci, 10, 1046–1055. · DOI
  32. Lamzin VS and Wilson KS (1993) Automated refinement of protein models. Acta Crystallogr D, 49, 129–147. · DOI
  33. Laskowski RA, Macarthur MW, Moss DS and Thornton JM (1993) Procheck—a program to check the stereochemical quality of protein structures. J Appl Crystallogr, 26, 283–291. · DOI · Paper page
  34. Law CL, Ewings MK, Chaudhary PM, Solow SA, Yun TJ, Marshall AJ, Hood L and Clark EA (1999) GrpL, a Grb2‐related adaptor protein, interacts with SLP‐76 to regulate nuclear factor of activated T cell activation. J Exp Med, 189, 1243–1253. · DOI
  35. Letunic I et al. (2002) Recent improvements to the SMART domain‐based sequence annotation resource. Nucleic Acids Res, 30, 242–244. · DOI
  36. Lewitzky M, Kardinal C, Gehring NH, Schmidt EK, Konkol B, Eulitz M, Birchmeier W, Schaeper U and Feller SM (2001) The C‐terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP‐76 which lack the SH3‐typical P–x–x–P core motif. Oncogene, 20, 1052–1062. · DOI · Paper page
  37. Lim WA (1996) Reading between the lines: SH3 recognition of an intact protein. Structure, 4, 657–659. · DOI
  38. Lim WA, Richards FM and Fox RO (1994) Structural determinants of peptide‐binding orientation and of sequence specificity in SH3 domains. Nature, 372, 375–379. · DOI
  39. Lin RS, Rodriguez C, Veillette A and Lodish HF (1998) Zinc is essential for binding of p56(lck) to CD4 and CD8alpha. J Biol Chem, 273, 32878–32882. · DOI
  40. Liu SK and McGlade CJ (1998) Gads is a novel SH2 and SH3 domain‐containing adaptor protein that binds to tyrosine‐phosphorylated Shc. Oncogene, 17, 3073–3082. · DOI
  41. Liu SK, Fang N, Koretzky GA and McGlade CJ (1999) The hematopoietic‐specific adaptor protein gads functions in T‐cell signaling via interactions with the SLP‐76 and LAT adaptors. Curr Biol, 9, 67–75. · DOI
  42. Liu SK, Smith CA, Arnold R, Kiefer F and McGlade CJ (2000) The adaptor protein Gads (Grb2‐related adaptor downstream of Shc) is implicated in coupling hemopoietic progenitor kinase‐1 to the activated TCR. J Immunol, 165, 1417–1426. · DOI
  43. Liu SK, Berry DM and McGlade CJ (2001) The role of Gads in hematopoietic cell signalling. Oncogene, 20, 6284–6290. · DOI
  44. Lock LS, Royal I, Naujokas MA and Park M (2000) Identification of an atypical Grb2 carboxyl‐terminal SH3 domain binding site in Gab docking proteins reveals Grb2‐dependent and ‐independent recruitment of Gab1 to receptor tyrosine kinases. J Biol Chem, 275, 31536–31545. · DOI · Paper page
  45. Manser E, Loo TH, Koh CG, Zhao ZS, Chen XQ, Tan L, Tan I, Leung T and Lim L (1998) PAK kinases are directly coupled to the PIX family of nucleotide exchange factors. Mol Cell, 1, 183–192. · DOI
  46. Mayer BJ (2001) SH3 domains: complexity in moderation. J Cell Sci, 114, 1253–1263. · DOI
  47. Merritt EA and Murphy MEP (1994) Raster3d Version‐2.0—a program for photorealistic molecular graphics. Acta Crystallogr D, 50, 869–873. · DOI
  48. Mongiovi AM, Romano PR, Panni S, Mendoza M, Wong WT, Musacchio A, Cesareni G and Di Fiore PP (1999) A novel peptide–SH3 interaction. EMBO J, 18, 5300–5309. · DOI
  49. Murshudov GN, Vagin AA and Dodson EJ (1997) Refinement of macromolecular structures by the maximum likelihood method. Acta Crystallogr D, 53, 240–255. · DOI
  50. Musacchio A (2002) How SH3 domains recognize proline. Adv Protein Chem, 61, 211–268. · DOI
  51. Naviglio S, Mattecucci C, Matoskova B, Nagase T, Nomura N, Di Fiore PP and Draetta GF (1998) UBPY: a growth‐regulated human ubiquitin isopeptidase. EMBO J, 17, 3241–3250. · DOI · Paper page
  52. Nicholls A, Sharp KA and Honig B (1991) Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins, 11, 281–296. · DOI
  53. Nishida M, Nagata K, Hachimori Y, Horiuchi M, Ogura K, Mandiyan V, Schlessinger J and Inagaki F (2001) Novel recognition mode between Vav and Grb2 SH3 domains. EMBO J, 20, 2995–3007. · DOI
  54. Ogura K, Nagata K, Horiuchi M, Ebisui E, Hasuda T, Yuzawa S, Nishida M, Hatanaka H and Inagaki F (2002) Solution structure of N‐terminal SH3 domain of Vav and the recognition site for Grb2 C‐terminal SH3 domain. J Biomol NMR, 22, 37–46. · DOI
  55. Otwinowski Z (1993) In Proceedings of the CCP4 Study Weekend: Data Collection and Processing. (Sawyer,L., Isaacs,N. and Bailey,S. (eds), pp. 56–62, SERC Daresbury Laboratory, Daresbury, England.
  56. Otwinowski Z and Minor W (1997) Processing of X‐ray diffraction data collected in oscillation mode. Macromol Crystallogr, 276, 307–326.
  57. Perrakis A, Morris R and Lamzin VS (1999) Automated protein model building combined with iterative structure refinement. Nat Struct Biol, 6, 458–463. · DOI
  58. Pidcock E and Moore GR (2001) Structural characteristics of protein binding sites for calcium and lanthanide ions. J Biol Inorg Chem, 6, 479–489. · DOI
  59. Qiu M, Hua S, Agrawal M, Li G, Cai J, Chan E, Zhou H, Luo Y and Liu M (1998) Molecular cloning and expression of human grap‐2, a novel leukocyte‐specific SH2‐ and SH3‐containing adaptor‐like protein that binds to gab‐1. Biochem Biophys Res Commun, 253, 443–447. · DOI
  60. Ramakrishnan V, Finch JT, Graziano V, Lee PL and Sweet RM (1993) Crystal structure of globular domain of histone H5 and its implications for nucleosome binding. Nature, 362, 219–223. · DOI
  61. Rodriguez‐Arguelles MC, Belicchi Ferrari M, Gasparri Fava G, Pelizzi C, Tarasconi P, Albertini R, Dall'Aglio PP, Lunghi P and Pinelli S (1995) 2,6‐Diacetylpyridine bis(thiosemicarbazones) zinc complexes: synthesis, structure and biological activity. J Inorg Biochem, 58, 157–175. · DOI
  62. Schultz J, Milpetz F, Bork P and Ponting CP (1998) SMART, a simple modular architecture research tool: identification of signaling domains. Proc Natl Acad Sci USA, 95, 5857–5864. · DOI
  63. Stuart DI, Levine M, Muirhead H and Stammers DK (1979) Crystal structure of cat muscle pyruvate kinase at a resolution of 2.6 Å. J Mol Biol, 134, 109–142. · DOI
  64. Terwilliger TC (2001) Maximum‐likelihood density modification using pattern recognition of structural motifs. Acta Crystallogr D, 57, 1755–1762. · DOI
  65. Terwilliger TC and Berendzen J (1999) Automated MAD and MIR structure solution. Acta Crystallogr D, 55, 849–861. · DOI
  66. Thompson JD, Higgins DG and Gibson TJ (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position‐specific gap penalties and weight matrix choice. Nucleic Acids Res, 22, 4673–4680. · DOI · Paper page
  67. Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F and Higgins DG (1997) The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res, 25, 4876–4882. · DOI
  68. Tomlinson MG, Lin J and Weiss A (2000) Lymphocytes with a complex: adapter proteins in antigen receptor signaling. Immunol Today, 21, 584–591. · DOI
  69. Van Duyne GD, Standaert RF, Karplus PA, Schreiber SL and Clardy J (1993) Atomic structures of the human immunophilin FKBP‐12 complexes with FK506 and rapamycin. J Mol Biol, 229, 105–124. · DOI
  70. Wellinghausen N and Rink L (1998) The significance of zinc for leukocyte biology. J Leukoc Biol, 64, 571–577. · DOI
  71. Wu X, Knudsen B, Feller SM, Zheng J, Sali A, Cowburn D, Hanafusa H and Kuriyan J (1995) Structural basis for the specific interaction of lysine‐containing proline‐rich peptides with the N‐terminal SH3 domain of c‐Crk. Structure, 3, 215–226. · DOI
  72. Xia C, Bao Z, Tabassam F, Ma W, Qiu M, Hua S and Liu M (2000) GCIP, a novel human grap2 and cyclin D interacting protein, regulates E2F‐mediated transcriptional activity. J Biol Chem, 275, 20942–20948. · DOI
  73. Yankee TM, Solow SA, Draves KD and Clark EA (2003) Expression of the grb2‐related protein of the lymphoid system in B cell subsets enhances B cell antigen receptor signaling through mitogen‐activated protein kinase pathways. J Immunol, 170, 349–355. · DOI
  74. Yoder J, Pham C, Iizuka YM, Kanagawa O, Liu SK, McGlade J and Cheng AM (2001) Requirement for the SLP‐76 adaptor GADS in T cell development. Science, 291, 1987–1991. · DOI
  75. Zheng N, Wang P, Jeffrey PD and Pavletich NP (2000) Structure of a c‐Cbl–UbcH7 complex: RING domain function in ubiquitin–protein ligases. Cell, 102, 533–539. · DOI · Paper page
  76. Zugaza JL, Lopez‐Lago MA, Caloca MJ, Dosil M, Movilla N and Bustelo XR (2002) Structural determinants for the biological activity of Vav proteins. J Biol Chem, 277, 45377–45392. · DOI

Cited by

Sorted by citations

Metadata

Authors
Harkiolaki, M., Lewitzky, M., Gilbert, R. J. C., Jones, E., Bourette, R. P., Mouchiroud, G., Sondermann, H., Moarefi, I., & Feller, S. M.
Venue
The EMBO Journal
Publisher
Springer Science and Business Media LLC
Published
2003-06-01
Volume
22
Issue
11
Pages
2571-2582
ISSN
  • 0261-4189
  • 1460-2075
DOI
10.1093/emboj/cdg258
Cited by
102
References
0
Language
en
Licence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review