The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Exercise testing to stratify risk in aortic stenosis
Open accessAbstract
AIMS: The aims of this study were to assess the accuracy of exercise testing in predicting symptom onset within 12 months in patients with asymptomatic aortic stenosis and to establish the criteria that define a positive test. METHODS AND RESULTS: A total of 125 patients with aortic stenosis [effective orifice area (EOA) 0.9+/-0.2 cm2] were assessed by Specific Activity Scale (SAS) classification, transthoracic echocardiography, and treadmill exercise testing using the modified Bruce protocol. During follow-up, 36 patients (29%) developed spontaneous symptoms within 12 months. Of these, 26 (72%) had had symptoms revealed by exercise testing and 24 (67%) had severe stenosis (EOA < or = 0.8 cm2). Exercise-limiting symptoms were the only independent predictors of outcome at 12 months, and an abnormal blood pressure response or ST segment depression did not improve the accuracy of the exercise test. The positive predictive accuracy for exercise-induced symptoms was 57% in the whole population and 79% for patients aged <70 in SAS Class I. The negative predictive accuracy was 87% in the whole population and 86% in the subgroup. CONCLUSION: A significant proportion of patients with apparently asymptomatic aortic stenosis experience limiting symptoms on treadmill exercise testing. The subsequent development of spontaneous symptoms is strongly related to the severity of stenosis and to limiting symptoms on exercise testing, but less so to an abnormal blood pressure response or ST segment depression.
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Cites
Sahn, D. J., DeMaria, A., Kisslo, J., & Weyman, A. (1978) · Circulation · doi:10.1161/01.cir.58.6.1072 · Cited by 7,430
Committee Members, Gibbons, R. J., Balady, G. J., Timothy Bricker, J., Chaitman, B. R., Fletcher, G. F., Froelicher, V. F., Mark, D. B., McCallister, B. D., Mooss, A. N., et al. (2002) · Circulation · doi:10.1161/01.cir.0000034670.06526.15 · Cited by 2,607
Predictors of Outcome in Severe, Asymptomatic Aortic Stenosis
Rosenhek, R., Binder, T., Porenta, G., Lang, I., Christ, G., Schemper, M., Maurer, G., & Baumgartner, H. (2000) · New England Journal of Medicine · doi:10.1056/nejm200008313430903 · Cited by 1,338
Otto, C. M., Burwash, I. G., Legget, M. E., Munt, B. I., Fujioka, M., Healy, N. L., Kraft, C. D., Miyake-Hull, C. Y., & Schwaegler, R. G. (1997) · Circulation · doi:10.1161/01.cir.95.9.2262 · Cited by 1,146
Gibbons, R. J., Balady, G. J., Beasley, J. W., FAAFP, Bricker, J. T., Duvernoy, W. F. C., Froelicher, V. F., Mark, D. B., Marwick, T. H., McCallister, B. D., et al. (1997) · Circulation · doi:10.1161/01.cir.96.1.345 · Cited by 1,094
Bonow, R. O., Carabello, B., de Leon, A. C., Edmunds, L. H., Fedderly, B. J., Freed, M. D., Gaasch, W. H., McKay, C. R., Nishimura, R. A., O’Gara, P. T., et al. (1998) · Circulation · doi:10.1161/01.cir.98.18.1949 · Cited by 1,034
Goldman, L., Hashimoto, B., Cook, E. F., & Loscalzo, A. (1981) · Circulation · doi:10.1161/01.cir.64.6.1227 · Cited by 978
Guidelines for exercise testing
Feild, M. D. J. (1986) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(86)80208-x · Cited by 527
Mild and moderate aortic stenosis Natural history and risk stratification by echocardiography
Rosenhek, R. (2004) · European Heart Journal · doi:10.1016/j.ehj.2003.12.002 · Cited by 461
The natural history of adults with asymptomatic, hemodynamically significant aortic stenosis
Pellikka, P. A., Nishimura, R. A., Bailey, K. R., & Tajik, A. J. (1990) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(90)90234-g · Cited by 393
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2021 ESC/EACTS Guidelines for the management of valvular heart disease
Vahanian, A., Beyersdorf, F., Praz, F., Milojevic, M., Baldus, S., Bauersachs, J., Capodanno, D., Conradi, L., De Bonis, M., De Paulis, R., et al. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehab395 · Cited by 5,685
Otto, C. M., Nishimura, R. A., Bonow, R. O., Carabello, B. A., Erwin, J. P., Gentile, F., Jneid, H., Krieger, E. V., Mack, M., McLeod, C., et al. (2021) · Circulation · doi:10.1161/cir.0000000000000923 · Cited by 3,686
Guidelines on the management of valvular heart disease (version 2012)
Authors/Task Force Members, Vahanian, A., Alfieri, O., Andreotti, F., Antunes, M. J., Barón-Esquivias, G., Baumgartner, H., Borger, M. A., Carrel, T. P., De Bonis, M., et al. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehs109 · Cited by 3,559
2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease
Nishimura, R. A., Otto, C. M., Bonow, R. O., Carabello, B. A., Erwin, J. P., Guyton, R. A., O’Gara, P. T., Ruiz, C. E., Skubas, N. J., Sorajja, P., et al. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2014.02.536 · Cited by 3,523
Nishimura, R. A., Otto, C. M., Bonow, R. O., Carabello, B. A., Erwin, J. P., Guyton, R. A., O’Gara, P. T., Ruiz, C. E., Skubas, N. J., Sorajja, P., et al. (2014) · Circulation · doi:10.1161/cir.0000000000000029 · Cited by 2,566
Metadata
- Authors
- Das, P., Rimington, H., & Chambers, J.
- Venue
- European Heart Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-04-08
- Volume
- 26
- Issue
- 13
- Pages
- 1309-1313
- ISSN
- 0195-668X (ISSN-L)
- 1522-9645
- OpenAlex
- W2032377380
- Cited by
- 391
- References
- 21
- FWCI
- 12.73
- Type
- journal article
- Language
- en
- Open access
- bronze
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