The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Clinical impact of thrombectomy in acute ST-elevation myocardial infarction: an individual patient-data pooled analysis of 11 trials
Open accessAbstract
AIMS: Thrombectomy in patients with ST-elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI) is associated to better myocardial reperfusion. However, no single trial was adequately powered to asses the impact of thrombectomy on long-term clinical outcome and to identify patients at higher benefit. Thus, we sought to assess these issues in a collaborative individual patient-data pooled analysis of randomized studies (study acronym: ATTEMPT, number of registration: NCT00766740). METHODS AND RESULTS: Individual data of 2686 patients enrolled in 11 trials entered the pooled analysis. Primary endpoint of the study was all-cause mortality. Major adverse cardiac events (MACE) were considered as the occurrence of all-cause death and/or target lesion/vessel revascularization and/or myocardial infarction (MI). Subgroups analysis was planned according to type of thrombectomy device (manual or non-manual), diabetic status, IIb/IIIa-inhibitor therapy, ischaemic time, infarct-related artery, pre-PCI TIMI flow. Clinical follow-up was available in 2674 (99.6%) patients at a median of 365 days. Kaplan-Meier analysis showed that allocation to thrombectomy was associated with significantly lower all-cause mortality (P = 0.049). Thrombectomy was also associated with significantly reduced MACE (P = 0.011) and death + MI rate during the follow-up (P = 0.015). Subgroups analysis showed that thrombectomy is associated to improved survival in patients treated with IIb/IIIa-inhibitors (P = 0.045) and that the survival benefit is confined to patients treated in manual thrombectomy trials (P = 0.011). CONCLUSION: The present large pooled analysis of randomized trials suggests that thrombectomy (in particular manual thrombectomy) significantly improves the clinical outcome in patients with STEMI undergoing mechanical reperfusion and that its effect may be additional to that of IIb/IIIa-inhibitors.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722
Keeley, E. C., Boura, J. A., & Grines, C. L. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12113-7 · Cited by 4,361
Altman, R., Carreras, L., Díaz, R. S., Figueroa, E. B., Paolasso, E., Parodi, J. C., Cade, J. F., Donnan, G. A., Eadie, M. J., Gavaghan, T. P., et al. (1994) · Cited by 3,322
Antiplatelet Trialists' Collaboration (1994) · BMJ · doi:10.1136/bmj.308.6921.81 · Cited by 3,126
Authors/Task Force Members, Van de Werf, F., Bax, J., Betriu, A., Blomstrom-Lundqvist, C., Crea, F., Falk, V., Filippatos, G., Fox, K., Huber, K., et al. (2008) · European Heart Journal · doi:10.1093/eurheartj/ehn416 · Cited by 2,310
Self-citationvan ‘t Hof, A. W. J., Liem, A., Suryapranata, H., Hoorntje, J. C. A., de Boer, M.-J., & Zijlstra, F. (1998) · Circulation · doi:10.1161/01.cir.97.23.2302 · Cited by 1,307
Self-citationThrombus Aspiration during Primary Percutaneous Coronary Intervention
Svilaas, T., Vlaar, P. J., van der Horst, I. C., Diercks, G. F. H., de Smet, B. J. G. L., van den Heuvel, A. F. M., Anthonio, R. L., Jessurun, G. A., Tan, E.-S., Suurmeijer, A. J. H., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0706416 · Cited by 1,071
Self-citationVlaar, P. J., Svilaas, T., van der Horst, I. C., Diercks, G. F., Fokkema, M. L., de Smet, B. J., van den Heuvel, A. F., Anthonio, R. L., Jessurun, G. A., Tan, E.-S., et al. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60833-8 · Cited by 900
Self-citationGibson, C. M., Cannon, C. P., Murphy, S. A., Ryan, K. A., Mesley, R., Marble, S. J., McCabe, C. H., Van de Werf, F., & Braunwald, E. (2000) · Circulation · doi:10.1161/01.cir.101.2.125 · Cited by 858
Myocardial No-Reflow in Humans
Niccoli, G., Burzotta, F., Galiuto, L., & Crea, F. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.03.054 · Cited by 853
Self-citation
Cited by
Ibanez, B., James, S., Agewall, S., Antunes, M. J., Bucciarelli-Ducci, C., Bueno, H., Caforio, A. L. P., Crea, F., Goudevenos, J. A., Halvorsen, S., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehx393 · Cited by 9,728
Self-citationKushner, F. G., Hand, M., Smith, S. C., King, S. B., Anderson, J. L., Antman, E. M., Bailey, S. R., Bates, E. R., Blankenship, J. C., Casey, D. E., et al. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.10.015 · Cited by 1,911
(2011) · Europe PMC (PubMed Central) · Cited by 89
Metadata
- Authors
- Burzotta, F., De Vita, M., Gu, Y. L., Isshiki, T., Lefevre, T., Kaltoft, A., Dudek, D., Sardella, G., Orrego, P. S., Antoniucci, D., De Luca, L., Biondi-Zoccai, G. G. L., Crea, F., & Zijlstra, F.
- Venue
- European Heart Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-09-02
- Volume
- 30
- Issue
- 18
- Pages
- 2193-2203
- ISSN
- 0195-668X (ISSN-L)
- 1522-9645
- OpenAlex
- W2086359359
- Cited by
- 263
- References
- 25
- FWCI
- 19.97
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Clinical impact of thrombectomy in acute ST-elevation myocardial infarction: an individual patient-data pooled analysis of 11 trials. https://app.cochat.ai/papers/10.1093/eurheartj/ehp348
- The paper
- Burzotta, F., De Vita, M., Gu, Y. L., Isshiki, T., Lefevre, T., Kaltoft, A., Dudek, D., Sardella, G., Orrego, P. S., Antoniucci, D., De Luca, L., Biondi-Zoccai, G. G. L., Crea, F., & Zijlstra, F. (2009). Clinical impact of thrombectomy in acute ST-elevation myocardial infarction: an individual patient-data pooled analysis of 11 trials. European Heart Journal. https://doi.org/10.1093/eurheartj/ehp348
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
