The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Acute outcomes of MitraClip therapy for mitral regurgitation in high-surgical-risk patients: emphasis on adverse valve morphology and severe left ventricular dysfunction
Abstract
AIMS: We sought to assess the feasibility of catheter-based mitral valve repair using the MitraClip system in high-surgical-risk patients with mitral regurgitation (MR) > or =grade 3+. METHODS AND RESULTS: MitraClip therapy was performed in 51 consecutive patients [73 +/- 10 years; 34 (67%) men] with symptomatic functional [n = 35 (69%)] or organic MR [n = 16 (31%)]. Mean logistic EuroSCORE was 29 +/- 22%; Society of Thoracic Surgeons score was 15 +/- 11. Left ventricular (LV) ejection fraction was 36 +/- 17%. In 35 patients (69%), adverse mitral valve morphology and/or severe LV dysfunction were present. MitraClip implantation was successful in 49 patients (96%). Most patients [n = 34/49 (69%)] were treated with a single clip, whereas 14 patients (29%) received two clips and one patient received three clips. Mean device and fluoroscopy times were 105 +/- 65 min and 44 +/- 28 min, respectively. Procedure-related reduction in MR severity was one grade in 16 patients (31%), two grades in 24 patients (47%), and three grades in 9 patients (18%). Forty-four of the 49 successfully treated patients (90%) showed clinical improvement at discharge [NYHA functional class > or =III in 48 patients (98%) before and 16 patients (33%) after the procedure (P < 0.0001)]. There were no procedure-related major adverse events and no in-hospital mortality. CONCLUSION: Mitral valve repair using the MitraClip system was shown to be feasible in patients at high surgical risk primarily determined by an adverse mitral valve morphology and/or severe LV dysfunction.
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Lang, R. M., Bierig, M., Devereux, R. B., Flachskampf, F. A., Foster, E., Pellikka, P. A., Picard, M. H., Roman, M. J., Seward, J., Shanewise, J. S., et al. (2005) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2005.10.005 · Cited by 11,318
Cited by
Guidelines on the management of valvular heart disease (version 2012)
Authors/Task Force Members, Vahanian, A., Alfieri, O., Andreotti, F., Antunes, M. J., Barón-Esquivias, G., Baumgartner, H., Borger, M. A., Carrel, T. P., De Bonis, M., et al. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehs109 · Cited by 3,559
Auricchio, A., Schillinger, W., Meyer, S., Maisano, F., Hoffmann, R., Ussia, G. P., Pedrazzini, G. B., van der Heyden, J., Fratini, S., Klersy, C., et al. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.06.061 · Cited by 261
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Metadata
- Authors
- Franzen, O., Baldus, S., Rudolph, V., Meyer, S., Knap, M., Koschyk, D., Treede, H., Barmeyer, A., Schofer, J., Costard-Jackle, A., Schluter, M., Reichenspurner, H., & Meinertz, T.
- Venue
- European Heart Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-03-10
- Volume
- 31
- Issue
- 11
- Pages
- 1373-1381
- ISSN
- 0195-668X (ISSN-L)
- 1522-9645
- OpenAlex
- W2113026948
- Cited by
- 332
- References
- 1
- FWCI
- 32.29
- Type
- journal article
- Language
- en
- Open access
- closed
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- Franzen, O., Baldus, S., Rudolph, V., Meyer, S., Knap, M., Koschyk, D., Treede, H., Barmeyer, A., Schofer, J., Costard-Jackle, A., Schluter, M., Reichenspurner, H., & Meinertz, T. (2010). Acute outcomes of MitraClip therapy for mitral regurgitation in high-surgical-risk patients: emphasis on adverse valve morphology and severe left ventricular dysfunction. European Heart Journal. https://doi.org/10.1093/eurheartj/ehq050
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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