Short report: How often do UK primary care trials face recruitment delays?

What influences recruitment to randomised controlled trials? A review of trials funded by two UK funding agencies

McDonald, A. M., Knight, R. C., Campbell, M. K., Entwistle, V. A., Grant, A. M., Cook, J. A., Elbourne, D. R., Francis, D., Garcia, J., Roberts, I., et al. (2006) · Trials · doi:10.1186/1745-6215-7-9 · Cited by 946

Increasing recruitment to randomised trials: a review of randomised controlled trials

Watson, J. M., & Torgerson, D. J. (2006) · BMC Medical Research Methodology · doi:10.1186/1471-2288-6-34 · Cited by 333

How evidence based are recruitment strategies to randomized controlled trials in primary care? Experience from seven studies

Foy, R. (2003) · Family Practice · doi:10.1093/fampra/20.1.83 · Cited by 160

Financial impact of the hospital pharmacy’s participation in clinical trials

López-Rico, I., Vives, R., Niebla, M. C., Cerdan, C., Morón, A., Ruiz, M. A., de Pedro, V. J., & Gómez-Valent, M. (2021) · European Journal of Hospital Pharmacy · doi:10.1136/ejhpharm-2020-002601 · Cited by 2

Trainee Principal Investigator Could Improve Recruitment in Trauma Trials: Review of Literature and Experience From a Trauma Center

Vas, A., D’sa, P., Gokhale, S., Agarwal, T., Roberts, G. L., & Mohanty, K. (2021) · Cureus · doi:10.7759/cureus.18920 · Cited by 2

Process evaluation of a multicentre randomised clinical trial of substituting surgical excisions of low-risk basal cell carcinomas from secondary to primary care

Noels, E., Lugtenberg, M., Wakkee, M., Ramdas, K., Bindels, P., Nijsten, T. E. C., & van den Bos, R. R. (2022) · BMJ Open · doi:10.1136/bmjopen-2020-047745 · Cited by 1

“In Their Own Words”: A Qualitative Exploration of Lived Experience and Healthcare Professional Perspectives on Evaluating a Digital Intervention for Binge Eating

Murphy, R., Osborne, E. L., Newhouse, N., & powell, J. A. (2025) · International Journal of Eating Disorders · doi:10.1002/eat.24539 · Cited by 1

Family Physicians as Clinical Trial Investigators? - A Qualitative Study of Physicians’ Experiences with a Double-Blind Clinical Trial

G, B. J. T. (2014) · Family Medicine & Medical Science Research · doi:10.4172/2327-4972.1000122 · Cited by 1

Exploring the challenges of recruiting to a randomised trial assessing the feasibility of treating White Coat Hypertension in older people in UK General Practices: A mixed-methods studyPreprint

Mensah, E., Ali, K., Okorie, M., Bremner, S. A., McAlister, C., Perry, N., & Rajkumar, C. (2022) · Research Square · doi:10.21203/rs.3.rs-1653643/v1 · Cited by 1

Parental attitudes to randomised controlled trials in primary dental care: A qualitative study

Coventry, H., Maguire, A., McColl, E., & Haighton, C. (2026) · PLoS ONE · doi:10.1371/journal.pone.0330055

Site visits to initiate recruitment in a clinical trial: does it matter who conducts the visit? Protocol for implementation in trials

Nollett, C. L., Kelson, M. J., & Hood, K. (2016) · Journal of Evidence-Based Medicine · doi:10.1111/jebm.12212 · Cited by 1

Pharmacists as the delivery channel for adherence support in asthma

Mes, M. A. (2019) · UCL Discovery (University College London)

Enhancing opportunistic recruitment and retention in primary care trials: lessons learned from a qualitative study embedded in the Cranberry for Urinary Tract Infection (CUTI) feasibility trial

Gbinigie, O. A., Boylan, A. R., Butler, C., Heneghan, C. J., & Tonkin-Crine, S. K. (2022) · BMC Family Practice · doi:10.1186/s12875-022-01796-7

Feasibility and Acceptability of a Cognitive Training Study in Individuals with Type 2 Diabetes Mellitus

Cooke, S., Pennington, K., Bridle, C., & Curtis, F. (2023) · Diabetology · doi:10.3390/diabetology4020016

SWAT 84: effects of same-day consent vs delayed consent on the recruitment and retention of trial participants—an observational SWAT

Elfghi, M., Jordan, F., Sultan, S., & Tawfick, W. A. (2023) · Trials · doi:10.1186/s13063-023-07727-w

ОСОБЛИВОСТІ ДЕРЖАВНОГО РЕГУЛЮВАННЯ ЗАЛУЧЕННЯ ПАЦІЄНТІВ У КЛІНІЧНІ ДОСЛІДЖЕННЯ ПІД ЧАС ВІЙНИ В УКРАЇНІ

Юрочко, Т. П., Шевченко, М. В., Maltseva, K., & Парастивюк, Є. М. (2023) · Таврійський науковий вісник Серія Публічне управління та адміністрування · doi:10.32782/tnv-pub.2023.6.16

Exploring the Challenges of Recruiting Older People for a Randomised Trial Assessing the Feasibility of Treating White Coat Hypertension in the UK General Practices: A Mixed-methods Study

Mensah, E., Ali, K., Okorie, M., Bremner, S. A., McAlister, C., Perry, N., & Rajkumar, C. (2024) · Current Hypertension Reviews · doi:10.2174/0115734021299574240809114921

Early structured communication between general practitioner, sick-listed patient, and employer: Results and lessons learned from a pragmatic trial in the Capacity Note project

Nordling, P., Nwaru, C. A., Nordeman, L., Skoglund, I., Larsson, M. E. H., Björkelund, C., & Hensing, G. K. E. (2024) · Primary Health Care Research & Development · doi:10.1017/s1463423624000574

Additional file 3 of Site-specific factors associated with clinical trial recruitment efficiency in general practice settings: a comparative descriptive analysis

Tew, M., Catchpool, M., Furler, J., Rue, K. D. L., Clarke, P., Manski-Nankervis, J.-A., & Dalziel, K. (2023) · Figshare · doi:10.6084/m9.figshare.22624048

Additional file 5 of Site-specific factors associated with clinical trial recruitment efficiency in general practice settings: a comparative descriptive analysis

Tew, M., Catchpool, M., Furler, J., Rue, K. D. L., Clarke, P., Manski-Nankervis, J.-A., & Dalziel, K. (2023) · Figshare · doi:10.6084/m9.figshare.22624054

Additional file 2 of Factors associated with recruitment to randomised controlled trials in general practice: a systematic mixed studies review

Moffat, K. R., Shi, W., Cannon, P., & Sullivan, F. (2023) · Figshare · doi:10.6084/m9.figshare.22616204

Additional file 1 of Factors associated with recruitment to randomised controlled trials in general practice: a systematic mixed studies review

Moffat, K. R., Shi, W., Cannon, P., & Sullivan, F. (2023) · Figshare · doi:10.6084/m9.figshare.22616201

Additional file 3 of Factors associated with recruitment to randomised controlled trials in general practice: a systematic mixed studies review

Moffat, K. R., Shi, W., Cannon, P., & Sullivan, F. (2023) · Figshare · doi:10.6084/m9.figshare.22616207

Additional file 4 of Site-specific factors associated with clinical trial recruitment efficiency in general practice settings: a comparative descriptive analysis

Tew, M., Catchpool, M., Furler, J., Rue, K. D. L., Clarke, P., Manski-Nankervis, J.-A., & Dalziel, K. (2023) · Figshare · doi:10.6084/m9.figshare.22624051

Additional file 1 of Site-specific factors associated with clinical trial recruitment efficiency in general practice settings: a comparative descriptive analysis

Tew, M., Catchpool, M., Furler, J., Rue, K. D. L., Clarke, P., Manski-Nankervis, J.-A., & Dalziel, K. (2023) · Figshare · doi:10.6084/m9.figshare.22624042

Additional file 1 of Enhancing opportunistic recruitment and retention in primary care trials: lessons learned from a qualitative study embedded in the Cranberry for Urinary Tract Infection (CUTI) feasibility trial

Gbinigie, O. A., Boylan, A.-M., Butler, C. C., Heneghan, C. J., & Tonkin-Crine, S. K. (2022) · Figshare · doi:10.6084/m9.figshare.20382024

Additional file 5 of Enhancing opportunistic recruitment and retention in primary care trials: lessons learned from a qualitative study embedded in the Cranberry for Urinary Tract Infection (CUTI) feasibility trial

Gbinigie, O. A., Boylan, A.-M., Butler, C. C., Heneghan, C. J., & Tonkin-Crine, S. K. (2022) · Figshare · doi:10.6084/m9.figshare.20382036

Additional file 1 of Changing patient preferences toward better trial recruitment: an ethical analysis

Al, P., Hey, S. P., Weijer, C., Gillies, K., McCleary, N., Yee, M.-L., Inglis, J., Presseau, J., & Brehaut, J. (2024) · Figshare · doi:10.6084/m9.figshare.26578199

Additional file 2 of Site-specific factors associated with clinical trial recruitment efficiency in general practice settings: a comparative descriptive analysis

Tew, M., Catchpool, M., Furler, J., Rue, K. D. L., Clarke, P., Manski-Nankervis, J.-A., & Dalziel, K. (2023) · Figshare · doi:10.6084/m9.figshare.22624045

Additional file 5 of Factors associated with recruitment to randomised controlled trials in general practice: a systematic mixed studies review

Moffat, K. R., Shi, W., Cannon, P., & Sullivan, F. (2023) · Figshare · doi:10.6084/m9.figshare.22616213

Additional file 3 of Enhancing opportunistic recruitment and retention in primary care trials: lessons learned from a qualitative study embedded in the Cranberry for Urinary Tract Infection (CUTI) feasibility trial

Gbinigie, O. A., Boylan, A.-M., Butler, C. C., Heneghan, C. J., & Tonkin-Crine, S. K. (2022) · Figshare · doi:10.6084/m9.figshare.20382030

Additional file 8 of Factors associated with recruitment to randomised controlled trials in general practice: a systematic mixed studies review

Moffat, K. R., Shi, W., Cannon, P., & Sullivan, F. (2023) · Figshare · doi:10.6084/m9.figshare.22616222

Additional file 2 of Enhancing opportunistic recruitment and retention in primary care trials: lessons learned from a qualitative study embedded in the Cranberry for Urinary Tract Infection (CUTI) feasibility trial

Gbinigie, O. A., Boylan, A.-M., Butler, C. C., Heneghan, C. J., & Tonkin-Crine, S. K. (2022) · Figshare · doi:10.6084/m9.figshare.20382027

Additional file 4 of Factors associated with recruitment to randomised controlled trials in general practice: a systematic mixed studies review

Moffat, K. R., Shi, W., Cannon, P., & Sullivan, F. (2023) · Figshare · doi:10.6084/m9.figshare.22616210

Additional file 4 of Enhancing opportunistic recruitment and retention in primary care trials: lessons learned from a qualitative study embedded in the Cranberry for Urinary Tract Infection (CUTI) feasibility trial

Gbinigie, O. A., Boylan, A.-M., Butler, C. C., Heneghan, C. J., & Tonkin-Crine, S. K. (2022) · Figshare · doi:10.6084/m9.figshare.20382033

Additional file 7 of Factors associated with recruitment to randomised controlled trials in general practice: a systematic mixed studies review

Moffat, K. R., Shi, W., Cannon, P., & Sullivan, F. (2023) · Figshare · doi:10.6084/m9.figshare.22616219

Additional file 2 of Changing patient preferences toward better trial recruitment: an ethical analysis

Al, P., Hey, S. P., Weijer, C., Gillies, K., McCleary, N., Yee, M.-L., Inglis, J., Presseau, J., & Brehaut, J. (2024) · Figshare · doi:10.6084/m9.figshare.26578202

Additional file 6 of Factors associated with recruitment to randomised controlled trials in general practice: a systematic mixed studies review

Moffat, K. R., Shi, W., Cannon, P., & Sullivan, F. (2023) · Figshare · doi:10.6084/m9.figshare.22616216

The preservation of childrenʼs oncofertility program “Snowflake”. First results

Kulyova, S. A., Карицкий, А. П., Lavrinovich, O., Берлев, И. В., & Татищева, Ю. А. (2026) · Russian Journal of Pediatric Hematology and Oncology · doi:10.21682/2311-1267-2026-13-1-39-44

Barriers and facilitators to patient recruitment to a cluster randomized controlled trial in primary care: lessons for future trials

Foster, J. M., Sawyer, S. M., Smith, L. D., Reddel, H. K., & Usherwood, T. P. (2015) · BMC Medical Research Methodology · doi:10.1186/s12874-015-0012-3 · Cited by 80

Recruiting patients to randomized trials in primary care: principles and case study

Bell-Syer, S. E., & Moffett, J. A. K. (2000) · Family Practice · doi:10.1093/fampra/17.2.187 · Cited by 92

Factors affecting patient recruitment to trials: qualitative research in general practice

van den Brink, M. J., Hummel, M. E., Lemstra, M., Berger, M. Y., Dekker, J. H., & Blanker, M. H. (2020) · BJGP Open · doi:10.3399/bjgpopen20x101056 · Cited by 31

Factors affecting general practitioner involvement in a randomised controlled trial in primary care.

Richardson, A. K., Sutherland, M., Wells, E., Toop, L. J., & Plumridge, L. W. (2002) · PubMed · Cited by 14

Factors Affecting General Practitioners' Recruitment of Patients into a Prospective Study

Peto, V., Coulter, A., & Bond, A. (1993) · Family Practice · doi:10.1093/fampra/10.2.207 · Cited by 105