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Mapping quantitative trait loci controlling milk production in dairy cattle by exploiting progeny testing.

Open access
Georges, M, Nielsen, D, Mackinnon, M, Mishra, A, Okimoto, R, Pasquino, A T, Sargeant, L S, Sorensen, A, Steele, M R, Zhao, X·1995·Genetics

Abstract

We have exploited "progeny testing" to map quantitative trait loci (QTL) underlying the genetic variation of milk production in a selected dairy cattle population. A total of 1,518 sires, with progeny tests based on the milking performances of > 150,000 daughters jointly, was genotyped for 159 autosomal microsatellites bracketing 1645 centimorgan or approximately two thirds of the bovine genome. Using a maximum likelihood multilocus linkage analysis accounting for variance heterogeneity of the phenotypes, we identified five chromosomes giving very strong evidence (LOD score > or = 3) for the presence of a QTL controlling milk production: chromosomes 1, 6, 9, 10 and 20. These findings demonstrate that loci with considerable effects on milk production are still segregating in highly selected populations and pave the way toward marker-assisted selection in dairy cattle breeding.

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Metadata

Authors
Georges, M., Nielsen, D., Mackinnon, M., Mishra, A., Okimoto, R., Pasquino, A. T., Sargeant, L. S., Sorensen, A., Steele, M. R., & Zhao, X.
Venue
Genetics
Published
1995-02-01
Volume
139
Issue
2
Pages
907-920
ISSN
  • 0016-6731 (ISSN-L)
  • 1943-2631
OpenAlex
W1935910619
Cited by
623
References
21
FWCI
22.92
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Mapping quantitative trait loci controlling milk production in dairy cattle by exploiting progeny testing. https://app.cochat.ai/papers/10.1093/genetics/139.2.907
The paper
Georges, M., Nielsen, D., Mackinnon, M., Mishra, A., Okimoto, R., Pasquino, A. T., Sargeant, L. S., Sorensen, A., Steele, M. R., & Zhao, X. (1995). Mapping quantitative trait loci controlling milk production in dairy cattle by exploiting progeny testing. Genetics. https://doi.org/10.1093/genetics/139.2.907

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