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Cited by 401

The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.

Frailty Among Community-Dwelling Elderly People in France: The Three-City Study

Open access
Avila-Funes, J. A., Helmer, C., Amieva, H., Barberger-Gateau, P., Goff, M. L., Ritchie, K., Portet, F., Carriere, I., Tavernier, B., Gutierrez-Robledo, L. M., Dartigues, J.-F.·2008·The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Abstract

BACKGROUND: To better understand the contribution of frailty to health-related outcomes in elderly persons, it seems valuable to explore data from cohort studies across the world in an attempt to establish a comprehensive definition. The purpose of this report is to show the characteristics of frailty and observe its prognosis in a large sample of French community-dwelling elderly persons. METHODS: We used data from 6078 persons 65 years old or older participating in the Three-City Study (3C). Frailty was defined as having at least three of the following criteria: weight loss, weakness, exhaustion, slowness, and low activity. Principal outcomes were incident disability, hospitalization, and death. Multiple covariates were used to test the predictive validity of frailty on these outcomes. RESULTS: Four hundred twenty-six individuals (7%) met frailty criteria. Participants classified as frail were significantly older, more likely to be female, and less educated and reported more chronic diseases, lower income, and poorer self-reported health status in comparison to nonfrail participants. In multivariate analysis, frailty was significantly associated with 4-year incidence of disability in activities of daily living (ADL) and instrumental ADL. However, frailty was marginally associated with incident hospitalization and was not a statistically significant predictor of incident mobility disability or mortality adjusting for potential confounding factors. CONCLUSIONS: Frailty is not specific to a subgroup or region of the world. The construct proposed by Fried and colleagues confirms its predictive validity for adverse-health outcomes, particularly for certain components of disability, thus suggesting that it may be useful in population screening and predicting service needs.

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Metadata

Authors
Avila-Funes, J. A., Helmer, C., Amieva, H., Barberger-Gateau, P., Goff, M. L., Ritchie, K., Portet, F., Carriere, I., Tavernier, B., Gutierrez-Robledo, L. M., & Dartigues, J.-F.
Venue
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
Published
2008-10-01
Volume
63
Issue
10
Pages
1089-1096
ISSN
  • 1079-5006 (ISSN-L)
  • 1758-535X
OpenAlex
W2141230909
Cited by
401
References
55
FWCI
6.45
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Frailty Among Community-Dwelling Elderly People in France: The Three-City Study. https://app.cochat.ai/papers/10.1093/gerona/63.10.1089
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Avila-Funes, J. A., Helmer, C., Amieva, H., Barberger-Gateau, P., Goff, M. L., Ritchie, K., Portet, F., Carriere, I., Tavernier, B., Gutierrez-Robledo, L. M., & Dartigues, J.-F. (2008). Frailty Among Community-Dwelling Elderly People in France: The Three-City Study. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. https://doi.org/10.1093/gerona/63.10.1089

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