The DOI matches its Crossref record; 108 of the 108 references it cites were found in a registry or an index.
Is Telomere Length a Biomarker of Aging? A Review
Open accessAbstract
Telomeres, the DNA-protein structures located at the ends of chromosomes, have been proposed to act as a biomarker of aging. In this review, the human evidence that telomere length is a biomarker of aging is evaluated. Although telomere length is implicated in cellular aging, the evidence suggesting telomere length is a biomarker of aging in humans is equivocal. More studies examining the relationships between telomere length and mortality and with measures that decline with "normal" aging in community samples are required. These studies would benefit from longitudinal measures of both telomere length and aging-related parameters.
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Cites
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Telomeres shorten during ageing of human fibroblasts
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Cellular senescence: when bad things happen to good cells
Campisi, J., & d'Adda di Fagagna, F. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2233 · Cited by 4,441
Telomere measurement by quantitative PCR
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Cited by
DNA methylation-based biomarkers and the epigenetic clock theory of ageing
Horvath, S., & Raj, K. (2018) · Nature Reviews Genetics · doi:10.1038/s41576-018-0004-3 · Cited by 3,095
Jylhävä, J., Pedersen, N. L., & Hägg, S. (2017) · EBioMedicine · doi:10.1016/j.ebiom.2017.03.046 · Cited by 1,240
Quantification of biological aging in young adults
Belsky, D. W., Caspi, A., Houts, R., Cohen, H. J., Corcoran, D. L., Danese, A., Harrington, H., Israel, S., Levine, M. E., Schaefer, J. D., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1506264112 · Cited by 1,012
Leucocyte telomere length and risk of cardiovascular disease: systematic review and meta-analysis
Haycock, P. C., Heydon, E. E., Kaptoge, S., Butterworth, A. S., Thompson, A., & Willeit, P. (2014) · BMJ · doi:10.1136/bmj.g4227 · Cited by 856
Telomere Length in Epidemiology: A Biomarker of Aging, Age-Related Disease, Both, or Neither?
Sanders, J. L., & Newman, A. B. (2013) · Epidemiologic Reviews · doi:10.1093/epirev/mxs008 · Cited by 537
Metadata
- Authors
- Mather, K. A., Jorm, A. F., Parslow, R. A., & Christensen, H.
- Venue
- The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-10-28
- Volume
- 66A
- Issue
- 2
- Pages
- 202-213
- ISSN
- 1079-5006 (ISSN-L)
- 1758-535X
- OpenAlex
- W2150751047
- Cited by
- 441
- References
- 108
- FWCI
- 10.27
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Is Telomere Length a Biomarker of Aging? A Review. https://app.cochat.ai/papers/10.1093/gerona/glq180
- The paper
- Mather, K. A., Jorm, A. F., Parslow, R. A., & Christensen, H. (2011). Is Telomere Length a Biomarker of Aging? A Review. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. https://doi.org/10.1093/gerona/glq180
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
