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Early microgliosis precedes neuronal loss and behavioural impairment in mice with a frontotemporal dementia-causing CHMP2B mutation

Clayton, Emma L, Mancuso, Renzo, Nielsen, Troels Tolstrup, Mizielinska, Sarah, Holmes, Holly, Powell, Nicholas, Norona, Frances, Overgaard Larsen, Jytte +12 more·2017·Human Molecular Genetics
DOI 10.1093/hmg/ddx003PMC PMC5409096
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  • Gliosis and glial dysfunction may precede neuronal loss in many neurodegenerative diseases.

    “there is a growing body of work showing that gliosis and glial dysfunction may precede neuronal loss in many neurodegenerative diseases (Hong et al., 2016; Clayton et al., 2017)”

    From MicroRNA Profiling Reveals Marker of Motor Neuron Disease in ALS Models (2017) · cites this paper as Clayton et al., 2017

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Cited by

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Authors
Clayton, E. L., Mancuso, R., Nielsen, T. T., Mizielinska, S., Holmes, H., Powell, N., Norona, F., Overgaard Larsen, J., Milioto, C., Wilson, K. M., Lythgoe, M. F., Ourselin, S., Nielsen, J. E., Johannsen, P., Holm, I., Collinge, J., Frej, A., Oliver, P. L., Gomez-Nicola, D., & Isaacs, A. M.
Venue
Human Molecular Genetics
Publisher
Oxford University Press (OUP)
Published
2017-01-16
Pages
ddx003
ISSN
  • 0964-6906
  • 1460-2083
DOI
10.1093/hmg/ddx003
PMC
PMC5409096
Cited by
10
References
12
Language
en

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