The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
The risks associated with pregnancy in women aged 35 years or older
Open accessAbstract
The obstetric risks of adverse outcome during pregnancy in women aged > or =35 years were quantified using a retrospective analysis of data from 385 120 singleton pregnancies in the North West Thames Region, UK, between 1988 and 1997. A comparison of pregnancy outcome was made on the basis of maternal age at delivery: 18-34 years (n = 336 462), 35-40 years (n = 41 327) and women aged > 40 years (n = 7331). Women aged <18 years (n = 5246) were excluded from the study. Data are presented as percentages of 18-34 year old women, 35-40 year old and > 40 year old women, with adjusted odds ratios (OR) according to age group. Pregnant women aged 35-40 years were at increased risk of: gestational diabetes, OR = 2.63 [99% confidence interval (CI) 2.40-2.89]; placenta praevia = 1.93 (1.58-2.35); breech presentation = 1.37 (1.28-1.47); operative vaginal delivery = 1.5 (1.43-1.57); elective Caesarean section = 1.77 (1.68-1.87); emergency Caesarean section = 1.59 (1.52-1.67); postpartum haemorrhage = 1.14 (1.09-1.19); delivery before 32 weeks gestation = 1.41 (1.24-1.61); birthweight below the 5th centile = 1.28 (1.20-1. 36); and stillbirth = 1.41 (1.17-1.70). Women aged >40 years had higher OR for the same risks. Pregnant women aged >/=35 years are at increased risk of complications in pregnancy compared with younger women.
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Cites
Increased Maternal Age and the Risk of Fetal Death
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Delayed Childbearing and the Outcome of Pregnancy
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The Pregnant Diabetic and Her Newborn
Farquhar, J. W. (1977) · Archives of Disease in Childhood · doi:10.1136/adc.52.8.671 · Cited by 406
Childbearing beyond age 40: pregnancy outcome in 24,032 cases
Gilbert, W. (1999) · Obstetrics & Gynecology · doi:10.1016/s0029-7844(98)00382-2 · Cited by 320
Older Maternal Age and Pregnancy Outcome: A Review of the Literature
HANSEN, J. P. (1986) · Obstetrical & Gynecological Survey · doi:10.1097/00006254-198611000-00024 · Cited by 241
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Long-term effects of delayed parenthood
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Cited by
Major risk factors for stillbirth in high-income countries: a systematic review and meta-analysis
Flenady, V., Koopmans, L., Middleton, P., Frøen, J. F., Smith, G. C., Gibbons, K., Coory, M., Gordon, A., Ellwood, D., McIntyre, H. D., et al. (2011) · The Lancet · doi:10.1016/s0140-6736(10)62233-7 · Cited by 1,247
Maternal age and adverse pregnancy outcome: a cohort study
Khalil, A., Syngelaki, A., Maiz, N., Zinevich, Y., & Nicolaides, K. H. (2013) · Ultrasound in Obstetrics & Gynecology · doi:10.1002/uog.12494 · Cited by 439
The Perinatal Effects of Delayed Childbearing
Joseph, K. S., Allen, A. C., Dodds, L., Turner, L. A., Scott, H., & Liston, R. (2005) · Obstetrics & Gynecology · doi:10.1097/01.aog.0000163256.83313.36 · Cited by 400
Maternal age and the risk of adverse pregnancy outcomes: a retrospective cohort study
Londero, A. P., Rossetti, E., Pittini, C., Cagnacci, A., & Driul, L. (2019) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-019-2400-x · Cited by 285
The Effect of Maternal Age on Adverse Birth Outcomes: Does Parity Matter?
Lisonkova, S., Janssen, P. A., Sheps, S. B., Lee, S. K., & Dahlgren, L. (2010) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/s1701-2163(16)34522-4 · Cited by 83
Metadata
- Authors
- Jolly, M.
- Venue
- Human Reproduction
- Publisher
- Oxford University Press (OUP)
- Published
- 2000-11-01
- Volume
- 15
- Issue
- 11
- Pages
- 2433-2437
- ISSN
- 0268-1161 (ISSN-L)
- 1460-2350
- OpenAlex
- W2146316950
- Cited by
- 490
- References
- 22
- FWCI
- 6.62
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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