The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Paternal age and maternal age are risk factors for miscarriage; results of a multicentre European study
Abstract
BACKGROUND: It is well known that miscarriage risk increases with age. However, studies usually investigate only maternal age effects. We investigated both maternal age and paternal age effects on miscarriage risk to provide insight into this frequent reproductive failure. METHODS: The last planned pregnancies (n = 3174) that ended in a birth or miscarriage were analysed in a retrospective population-based study on women aged 25-44 years in Denmark, Germany, Italy and Spain. Maternal and paternal ages were analysed together, using a single variable 'couple age' in a multivariate logistic regression analysis, with couples composed of a woman and a man both aged 20-29 years forming the reference group. RESULTS: After adjustment for various factors (e.g. reproductive history, country), we found that the risk of miscarriage was higher if the woman was aged > or = 35 years, as has already been reported in a number of studies. However, the increase in risk was much greater for couples composed of a woman aged > or = 35 years and of a man aged > or = 40 years. Potential source of bias (especially 'reproductive compensation') are discussed. CONCLUSIONS: The risk of an adverse pregnancy outcome is highest if both partners are advanced in age.
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Cites
(1990) · Choice Reviews Online · doi:10.5860/choice.27-3338 · Cited by 35,305
Incidence of early loss of pregnancy
Wilcox, A. J., Weinberg, C. R., O'Connor, J. F., Baird, D. D., Schlatterer, J. P., Canfield, R. E., Armstrong, E. G., & Nisula, B. C. (1988) · New England Journal of Medicine · doi:10.1056/nejm198807283190401 · Cited by 2,354
Maternal age and fetal loss: population based register linkage study
Andersen, A.-M. N. (2000) · BMJ · doi:10.1136/bmj.320.7251.1708 · Cited by 1,690 · cited 6×
“…reproductive events: infertility, spontaneous abortion, pregnancy complications (such as Caesarean section, pre-eclampsia), congenital abnormalities, maternal mortality and perinatal mortality, than do younger women (Schwartz and Mayaux, 1982; Newcomb et al., 1991; Nybo Andersen et al., 2000).”
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Cited by
Role of maternal age and pregnancy history in risk of miscarriage: prospective register based study
Magnus, M. C., Wilcox, A. J., Morken, N.-H., Weinberg, C. R., & Håberg, S. E. (2019) · BMJ · doi:10.1136/bmj.l869 · Cited by 698
Demographic and medical consequences of the postponement of parenthood
Schmidt, L., Sobotka, T., Bentzen, J. G., Nyboe Andersen, A., & on behalf of the ESHRE Reproduction and Society Task Force (2012) · Human Reproduction Update · doi:10.1093/humupd/dmr040 · Cited by 656
The effect of sperm DNA fragmentation on miscarriage rates: a systematic review and meta-analysis
Robinson, L., Gallos, I. D., Conner, S. J., Rajkhowa, M., Miller, D., Lewis, S., Kirkman-Brown, J., & Coomarasamy, A. (2012) · Human Reproduction · doi:10.1093/humrep/des261 · Cited by 629
The role of infection in miscarriage
Giakoumelou, S., Wheelhouse, N., Cuschieri, K., Entrican, G., Howie, S. E. M., & Horne, A. W. (2016) · Human Reproduction Update · doi:10.1093/humupd/dmv041 · Cited by 464
Sharma, R., Agarwal, A., Rohra, V. K., Assidi, M., Abu-Elmagd, M., & Turki, R. F. (2015) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-015-0028-x · Cited by 451
Metadata
- Authors
- de La Rochebrochard, E., & Thonneau, P.
- Venue
- Human Reproduction
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-06
- Volume
- 17
- Issue
- 6
- Pages
- 1649-1656
- ISSN
- 0268-1161 (ISSN-L)
- 1460-2350
- OpenAlex
- W2129337865
- Cited by
- 471
- References
- 3
- FWCI
- 12.38
- Type
- journal article
- Language
- en
- Open access
- closed
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- de La Rochebrochard, E., & Thonneau, P. (2002). Paternal age and maternal age are risk factors for miscarriage; results of a multicentre European study. Human Reproduction. https://doi.org/10.1093/humrep/17.6.1649
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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