The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Epigenetic risks related to assisted reproductive technologies: Epigenetics, imprinting, ART and icebergs?
Abstract
Recently, a series of case reports and small studies has suggested that births involving assisted reproductive technology (ART) may have an increased risk of imprinting disorders such as Beckwith-Wiedemann syndrome and Angelman syndrome. Herein, the significance and implications of these findings are discussed. It is speculated that, although such imprinting disorders may be shown to be only rare complications of ART, epigenetic errors might account for a much wider spectrum of ART-related complications than is recognized currently. Addressing these questions should be a priority for research on cohorts of ART children.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Fetal nutrition and cardiovascular disease in adult life
Barker, D. J. P., Godfrey, K. M., Gluckman, P. D., Harding, J. E., Owens, J. A., & Robinson, J. S. (1993) · The Lancet · doi:10.1016/0140-6736(93)91224-a · Cited by 2,753
Cited by
Epigenetics: Definition, Mechanisms and Clinical Perspective
Dupont, C., Armant, D., & Brenner, C. (2009) · Seminars in Reproductive Medicine · doi:10.1055/s-0029-1237423 · Cited by 799
Epigenetics and human disease: translating basic biology into clinical applications
Rodenhiser, D. (2006) · Canadian Medical Association Journal · doi:10.1503/cmaj.050774 · Cited by 473
Selective loss of imprinting in the placenta following preimplantation development in culture
Mann, M. R. W., Lee, S. S., Doherty, A. S., Verona, R. I., Nolen, L. D., Schultz, R. M., & Bartolomei, M. S. (2004) · Development · doi:10.1242/dev.01241 · Cited by 431
DMSO induces drastic changes in human cellular processes and epigenetic landscape in vitro
Verheijen, M., Lienhard, M., Schrooders, Y., Clayton, O., Nudischer, R., Boerno, S., Timmermann, B., Selevsek, N., Schlapbach, R., Gmuender, H., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-40660-0 · Cited by 403
Aberrant DNA methylation of imprinted loci in superovulated oocytes
Sato, A., Otsu, E., Negishi, H., Utsunomiya, T., & Arima, T. (2007) · Human Reproduction · doi:10.1093/humrep/del316 · Cited by 369
Metadata
- Authors
- Maher, E. R.
- Venue
- Human Reproduction
- Publisher
- Oxford University Press (OUP)
- Published
- 2003-12-01
- Volume
- 18
- Issue
- 12
- Pages
- 2508-2511
- ISSN
- 0268-1161 (ISSN-L)
- 1460-2350
- OpenAlex
- W2141567615
- Cited by
- 230
- References
- 1
- FWCI
- 9.21
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Epigenetic risks related to assisted reproductive technologies: Epigenetics, imprinting, ART and icebergs? https://app.cochat.ai/papers/10.1093/humrep/deg486
- The paper
- Maher, E. R. (2003). Epigenetic risks related to assisted reproductive technologies: Epigenetics, imprinting, ART and icebergs? Human Reproduction. https://doi.org/10.1093/humrep/deg486
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
