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The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

Live birth after autograft of ovarian tissue cryopreserved during childhood: Figure 1

Open access
Demeestere, Isabelle, Simon, Philippe, Dedeken, Laurence, Moffa, Federica, Tsépélidis, Sophie, Brachet, Cecile, Delbaere, Anne, Devreker, Fabienne, Ferster, Alina·2015·Human Reproduction

Abstract

Ovarian insufficiency is a major long-term adverse event, following the administration of a myeloablative conditioning regimen, and occurring in >80% of children and adolescents receiving such treatment for malignant or non-malignant disease. Cryopreservation of ovarian tissue is currently offered to preserve the fertility of these young patients. At least 35 live births have been reported after transplantation of cryopreserved ovarian tissue in adult patients, but the procedure remains unproven for ovarian tissue harvested at a prepubertal or pubertal age. We report here the first live birth after autograft of cryopreserved ovarian tissue in a woman with primary ovarian failure after a myeloablative conditioning regimen as part of a hematopoietic stem cell transplantation performed for homozygous sickle-cell anemia at age 14 years. This first report of successful fertility restoration after the graft of ovarian tissue cryopreserved before menarche offers reassuring evidence for the feasibility of the procedure when performed during childhood.

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Crossref · 10.1093/humrep/dev128

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Metadata

Authors
Demeestere, I., Simon, P., Dedeken, L., Moffa, F., Tsépélidis, S., Brachet, C., Delbaere, A., Devreker, F., & Ferster, A.
Venue
Human Reproduction
Published
2015-06-09
Volume
30
Issue
9
Pages
2107-2109
ISSN
  • 0268-1161 (ISSN-L)
  • 1460-2350
OpenAlex
W1929640095
Cited by
398
References
10
FWCI
46.58
Type
journal article
Language
en
Open access
bronze

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