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Cited by 494Ovarian function and disordersAdrenal Hormones and DisordersSexual Differentiation and Disorders

The DOI matches its Crossref record; 218 of the 222 references it cites were found in a registry or an index.

Epidemiology, diagnosis and management of hirsutism: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome Society

Escobar-Morreale, H.F., Carmina, E., Dewailly, D., Gambineri, A., Kelestimur, F., Moghetti, P., Pugeat, M., Qiao, J., Wijeyaratne, C.N., Witchel, S.F., Norman, R.J.·2012·Human Reproduction Update
DOI 10.1093/humupd/dmr042
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Abstract

BACKGROUND: Hirsutism, defined by the presence of excessive terminal hair in androgen-sensitive areas of the female body, is one of the most common disorders in women during reproductive age. METHODS: We conducted a systematic review and critical assessment of the available evidence pertaining to the epidemiology, pathophysiology, diagnosis and management of hirsutism. RESULTS: The prevalence of hirsutism is ~10% in most populations, with the important exception of Far-East Asian women who present hirsutism less frequently. Although usually caused by relatively benign functional conditions, with the polycystic ovary syndrome leading the list of the most frequent etiologies, hirsutism may be the presenting symptom of a life-threatening tumor requiring immediate intervention. CONCLUSIONS: Following evidence-based diagnostic and treatment strategies that address not only the amelioration of hirsutism but also the treatment of the underlying etiology is essential for the proper management of affected women, especially considering that hirsutism is, in most cases, a chronic disorder needing long-term follow-up. Accordingly, we provide evidence-based guidelines for the etiological diagnosis and for the management of this frequent medical complaint.

Overview

Integrity signals

Registry

Crossref · 10.1093/humupd/dmr042

Cites

218 of 218 references verified0 citation errors · 0 not checkable

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Citations

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1 retracted

Show all 222 references

Research works printed but not linked: 3

  1. Carmina, 2001, Hirsutism, alopecia and acne
  2. Devoto, 2000, [Treatment of hirsutism with spironolactone and with spironolactone plus dexamethasone], Rev Med Chil, 128, 868
  3. van der Spuy, 2008, Gonadotrophin-releasing hormone analogues for hirsutism (Protocol), Cochrane Database Syst Rev, CD001126

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Metadata

Authors
Escobar-Morreale, H. F., Carmina, E., Dewailly, D., Gambineri, A., Kelestimur, F., Moghetti, P., Pugeat, M., Qiao, J., Wijeyaratne, C. N., Witchel, S. F., & Norman, R. J.
Affiliations
  • Universidad de Alcalá (ES)
  • University of Palermo (IT)
  • Hôpital Jeanne de Flandre (FR)
  • IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola (IT)
  • University of Verona (IT)
  • Lyon 1 Université (FR)
  • Peking University Third Hospital (CN)
  • University of Colombo (LK)
  • University of Pittsburgh (US)
  • The University of Adelaide (AU)
ORCID
Venue
Human Reproduction Update
Publisher
Oxford University Press (OUP)
Published
2011-11-06
Volume
18
Issue
2
Pages
146-170
ISSN
  • 1355-4786 (ISSN-L)
  • 1460-2369
DOI
10.1093/humupd/dmr042
OpenAlex
W2119532054
Cited by
494
References
222
Citations by year
2026: 19 · 2025: 34 · 2024: 26 · 2023: 49 · 2022: 39 · 2021: 50 · 2020: 40 · 2019: 36 · 2018: 29 · 2017: 31 · 2016: 28 · 2015: 45 · 2014: 28 · 2013: 23 · 2012: 15
FWCI
23.94
Type
journal article
Language
en
Open access
closed
Locations
  • Human Reproduction Update (publishedVersion)
  • PubMed (publishedVersion)
  • Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna) (submittedVersion)
  • Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
  • Nova Science Publishers (Nova Science Publishers, Inc.) (submittedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Sexual Differentiation and Disorders
Keywords
hirsutism, hyperandrogenism, polycystic ovary syndrome, prevalence, pathophysiology, etiological diagnosis, long-term follow-up
MeSH terms
Androgens, Female, Hirsutism, Humans, Polycystic Ovary Syndrome, Societies, Medical, Hair Follicle

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