Utilizing Deep Learning to Analyze Whole Slide Images of Colonic Biopsies for Associations Between Eosinophil Density and Clinicopathologic Features in Active Ulcerative Colitis

Vande Casteele, Niels; Leighton, Jonathan A; Pasha, Shabana F; Cusimano, Frank; Mookhoek, Aart; Hagen, Catherine E; Rosty, Christophe; Pai, Reetesh K; Pai, Rish K

doi:10.1093/ibd/izab122

Utilizing Deep Learning to Analyze Whole Slide Images of Colonic Biopsies for Associations Between Eosinophil Density and Clinicopathologic Features in Active Ulcerative Colitis

Background Eosinophils have been implicated in the pathogenesis of ulcerative colitis and have been associated with disease course and therapeutic response. However, associations between eosinophil density, histologic activity, and clinical features have not been rigorously studied. Methods A dee…