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A Methodological Review of Non-Therapeutic Intervention Trials Employing Cluster Randomization, 1979–1989
Abstract
A methodological review is presented of 16 non-therapeutic intervention trials published over the last decade which have randomized intact clusters rather than individuals in treatment groups. Each of the trials was surveyed as to the information supplied on six methodological criteria. Although there is increasing recognition of the methodological issues associated with cluster randomization, many investigators are still not aware of the impact of this design on sample size requirements and analysis considerations. Investigators are urged to publish the cluster-specific event rates observed in their trials as a guide for the planning of future studies.
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Cited by
Consort 2010 statement: extension to cluster randomised trials
Campbell, M. K., Piaggio, G., Elbourne, D. R., Altman, D. G., & for the CONSORT Group (2012) · BMJ · doi:10.1136/bmj.e5661 · Cited by 3,510
Improving the Quality of Reporting of Randomized Controlled Trials: The CONSORT Statement
Begg, C. (1996) · JAMA · doi:10.1001/jama.1996.03540080059030 · Cited by 3,127
CONSORT statement: extension to cluster randomised trials
Campbell, M. K., Elbourne, D. R., & Altman, D. G. (2004) · BMJ · doi:10.1136/bmj.328.7441.702 · Cited by 2,557
Issues in the meta-analysis of cluster randomized trials
Donner, A., & Klar, N. (2002) · Statistics in Medicine · doi:10.1002/sim.1301 · Cited by 734
A Controlled Trial of a Critical Pathway for Treatment of Community-Acquired Pneumonia
Marrie, T. J. (2000) · JAMA · doi:10.1001/jama.283.6.749 · Cited by 731
Metadata
- Authors
- DONNER, A., BROWN, K. S., & BRASHER, P.
- Venue
- International Journal of Epidemiology
- Publisher
- Oxford University Press (OUP)
- Published
- 1990
- Volume
- 19
- Issue
- 4
- Pages
- 795-800
- ISSN
- 0300-5771 (ISSN-L)
- 1464-3685
- OpenAlex
- W2078780468
- Cited by
- 174
- References
- 0
- FWCI
- 1.28
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: A Methodological Review of Non-Therapeutic Intervention Trials Employing Cluster Randomization, 1979–1989. https://app.cochat.ai/papers/10.1093/ije/19.4.795
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- DONNER, A., BROWN, K. S., & BRASHER, P. (1990). A Methodological Review of Non-Therapeutic Intervention Trials Employing Cluster Randomization, 1979–1989. International Journal of Epidemiology. https://doi.org/10.1093/ije/19.4.795
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
