The DOI matches its Crossref record.
Associations of Body Mass and Fat Distribution with Sex Hormone Concentrations in Postmenopausal Women
Abstract
The associations of body mass and body fat distribution, as measured by waist-to-hip circumference ratio, with serum concentrations of sex hormones and sex hormone binding globulin were examined in 88 postmenopausal women. Body mass index (BMI) was significantly and negatively associated with sex hormone binding globulin (SHBG) (r = -0.41), luteinizing hormone (LH) (r = -0.40) and follicle stimulating hormone (FSH) (r = -0.38) and was also significantly positively associated with both total and free oestradiol (r = 0.40 and 0.45, respectively). Waist-to-hip circumference ratio was significantly negatively correlated with SHBG (r = -0.53), LH (r = -0.35), and FSH (r = -0.35). After adjustment for BMI and other related factors, waist-to-hip circumference ratio was significantly and negatively associated with SHBG, LH, and FSH, and demonstrated a significant curvilinear relationship with free testosterone. These results suggest that in postmenopausal women, abdominal adiposity is associated with a relatively more androgenic sex hormone profile.
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Cited by
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Risch, H. A. (1998) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/90.23.1774 · Cited by 771
Folsom, A. R., Kushi, L. H., Anderson, K. E., Mink, P. J., Olson, J. E., Hong, C.-P., Sellers, T. A., Lazovich, D., & Prineas, R. J. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.14.2117 · Cited by 684
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Metadata
- Authors
- KAYE, S. A., FOLSOM, A. R., SOLER, J. T., PRINEAS, R. J., & POTTER, J. D.
- Venue
- International Journal of Epidemiology
- Publisher
- Oxford University Press (OUP)
- Published
- 1991
- Volume
- 20
- Issue
- 1
- Pages
- 151-156
- ISSN
- 0300-5771 (ISSN-L)
- 1464-3685
- OpenAlex
- W2170898581
- Cited by
- 226
- References
- 0
- FWCI
- 5.65
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Associations of Body Mass and Fat Distribution with Sex Hormone Concentrations in Postmenopausal Women. https://app.cochat.ai/papers/10.1093/ije/20.1.151
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- KAYE, S. A., FOLSOM, A. R., SOLER, J. T., PRINEAS, R. J., & POTTER, J. D. (1991). Associations of Body Mass and Fat Distribution with Sex Hormone Concentrations in Postmenopausal Women. International Journal of Epidemiology. https://doi.org/10.1093/ije/20.1.151
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