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Cited by 312

The DOI matches its Crossref record; 99 of the 99 references it cites were found in a registry or an index.

Tick-Borne Zoonoses in the United States: Persistent and Emerging Threats to Human Health

Open access
Eisen, Rebecca J, Kugeler, Kiersten J, Eisen, Lars, Beard, Charles B, Paddock, Christopher D·2017·ILAR Journal

Abstract

In the United States, ticks transmit the greatest diversity of arthropod-borne pathogens and are responsible for the most cases of all vector-borne diseases. In recent decades, the number of reported cases of notifiable tick-borne diseases has steadily increased, geographic distributions of many ticks and tick-borne diseases have expanded, and new tick-borne disease agents have been recognized. In this review, we (1) describe the known disease agents associated with the most commonly human-biting ixodid ticks, (2) review the natural histories of these ticks and their associated pathogens, (3) highlight spatial and temporal changes in vector tick distributions and tick-borne disease occurrence in recent decades, and (4) identify knowledge gaps and barriers to more effective prevention of tick-borne diseases. We describe 12 major tick-borne diseases caused by 15 distinct disease agents that are transmitted by the 8 most commonly human-biting ixodid ticks in the United States. Notably, 40% of these pathogens were described within the last two decades. Our assessment highlights the importance of animal studies to elucidate how tick-borne pathogens are maintained in nature, as well as advances in molecular detection of pathogens which has led to the discovery of several new tick-borne disease agents.

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Metadata

Authors
Eisen, R. J., Kugeler, K. J., Eisen, L., Beard, C. B., & Paddock, C. D.
Venue
ILAR Journal
Published
2017
Volume
58
Issue
3
Pages
319-335
ISSN
  • 1084-2020 (ISSN-L)
  • 1930-6180
OpenAlex
W2600291485
Cited by
312
References
99
FWCI
18.06
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Tick-Borne Zoonoses in the United States: Persistent and Emerging Threats to Human Health. https://app.cochat.ai/papers/10.1093/ilar/ilx005
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Eisen, R. J., Kugeler, K. J., Eisen, L., Beard, C. B., & Paddock, C. D. (2017). Tick-Borne Zoonoses in the United States: Persistent and Emerging Threats to Human Health. ILAR Journal. https://doi.org/10.1093/ilar/ilx005

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