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Cited by 287

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Hepatitis B e Antigen and Infectivity of Hepatitis B Virus

Shikata, T., Karasawa, T., Abe, K., Uzawa, T., Suzuki, H., Oda, T., Imai, M., Mayumi, M., Moritsugu, Y.·1977·Journal of Infectious Diseases

Abstract

For confirmation of the difference in the infectivity of hepatitis B surface antigen (HBS Ag)-positive serum according to differences in the e antigen system, four chimpanzees were inoculated with serum positive for hepatitis B e antigen (HBe Ag), and three chimpanzees were inoculated with serum positive for antibody to HBe Ag (anti-HBe). Since the infectivity titrations are not yet completed, the end infectivity titer of each serum is not known. All four chimpanzees given injections of 10(-1), 10(-4), or 10(-8) dilutions of HBe Ag-positive serum developed hepatitis B virus infection, whereas the one chimpanzee injected with undiluted anti-HBe-positive serum became infected, and other chimpanzees injected with diluted anti-HBe-positive sera did not. As judged from the length of the incubation period before appearance of HBS Ag in blood, there seemed to be a remarkable difference in infectivity between the HBe Ag-positive serum and the anti-HBe-positive serum; the former serum was 10(8) times more infectious than the latter.

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Metadata

Authors
Shikata, T., Karasawa, T., Abe, K., Uzawa, T., Suzuki, H., Oda, T., Imai, M., Mayumi, M., & Moritsugu, Y.
Venue
Journal of Infectious Diseases
Published
1977-10-01
Volume
136
Issue
4
Pages
571-576
ISSN
  • 0022-1899 (ISSN-L)
  • 1537-6613
OpenAlex
W2058402734
Cited by
287
References
2
FWCI
11.21
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Hepatitis B e Antigen and Infectivity of Hepatitis B Virus. https://app.cochat.ai/papers/10.1093/infdis/136.4.571
The paper
Shikata, T., Karasawa, T., Abe, K., Uzawa, T., Suzuki, H., Oda, T., Imai, M., Mayumi, M., & Moritsugu, Y. (1977). Hepatitis B e Antigen and Infectivity of Hepatitis B Virus. Journal of Infectious Diseases. https://doi.org/10.1093/infdis/136.4.571

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.