The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Hepatitis B e Antigen and Infectivity of Hepatitis B Virus
Abstract
For confirmation of the difference in the infectivity of hepatitis B surface antigen (HBS Ag)-positive serum according to differences in the e antigen system, four chimpanzees were inoculated with serum positive for hepatitis B e antigen (HBe Ag), and three chimpanzees were inoculated with serum positive for antibody to HBe Ag (anti-HBe). Since the infectivity titrations are not yet completed, the end infectivity titer of each serum is not known. All four chimpanzees given injections of 10(-1), 10(-4), or 10(-8) dilutions of HBe Ag-positive serum developed hepatitis B virus infection, whereas the one chimpanzee injected with undiluted anti-HBe-positive serum became infected, and other chimpanzees injected with diluted anti-HBe-positive sera did not. As judged from the length of the incubation period before appearance of HBS Ag in blood, there seemed to be a remarkable difference in infectivity between the HBe Ag-positive serum and the anti-HBe-positive serum; the former serum was 10(8) times more infectious than the latter.
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Cites
Okada, K., Kamiyama, I., Inomata, M., Imai, M., Miyakawa, Y., & Mayumi, M. (1976) · New England Journal of Medicine · doi:10.1056/nejm197604012941402 · Cited by 728
Self-citationHepatitis B Virus Infection in Chimpanzees: Titration of Subtypes
Barker, L. F., Maynard, J. E., Purcell, R. H., Hoofnagle, J. H., Berquist, K. R., London, W. T., Gerety, R. J., & Krushak, D. H. (1975) · The Journal of Infectious Diseases · doi:10.1093/infdis/132.4.451 · Cited by 147
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Frid, A. H., Kreugel, G., Grassi, G., Halimi, S., Hicks, D., Hirsch, L. J., Smith, M. J., Wellhoener, R., Bode, B. W., Hirsch, I. B., et al. (2016) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2016.06.010 · Cited by 286
Metadata
- Authors
- Shikata, T., Karasawa, T., Abe, K., Uzawa, T., Suzuki, H., Oda, T., Imai, M., Mayumi, M., & Moritsugu, Y.
- Venue
- Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1977-10-01
- Volume
- 136
- Issue
- 4
- Pages
- 571-576
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2058402734
- Cited by
- 287
- References
- 2
- FWCI
- 11.21
- Type
- journal article
- Language
- en
- Open access
- closed
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- Shikata, T., Karasawa, T., Abe, K., Uzawa, T., Suzuki, H., Oda, T., Imai, M., Mayumi, M., & Moritsugu, Y. (1977). Hepatitis B e Antigen and Infectivity of Hepatitis B Virus. Journal of Infectious Diseases. https://doi.org/10.1093/infdis/136.4.571
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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