The DOI matches its Crossref record.
Prevention of Colonization of the Urinary Tract of Mice with Escherichia coli by Blocking of Bacterial Adherence with Methyl -D-Mannopyranoside
Abstract
Methyl alpha-D-mannopyranoside (alpha MM), a competitor inhibitor of the binding of mannose by Escherichia coli, was tested for its ability to prevent infection of the urinary tract of mice with infective strains of the organisms. Injection of the bacteria in the presence of the drug resulted in a considerable reduction in the number of bacteriuric mice. In this system alpha MM was inactive against Proteus mirabilis in accordance with its inability to inhibit the adherence of this organism to epithelial cells in vitro, and methyl alpha-D-glucopyranoside proved inactive against both E. coli and P. mirabilis.
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Citations
Cited by
Beachey, E. H. (1981) · Journal of Infectious Diseases · doi:10.1093/infdis/143.3.325 · Cited by 1,411
Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands
Kitov, P. I., Sadowska, J. M., Mulvey, G., Armstrong, G. D., Ling, H., Pannu, N. S., Read, R. J., & Bundle, D. R. (2000) · Nature · doi:10.1038/35001095 · Cited by 869
Zafriri, D., Ofek, I., Adar, R., Pocino, M., & Sharon, N. (1989) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.33.1.92 · Cited by 417
Self-citationSaliva-Bacterium Interactions in Oral Microbial Ecology
Scannapieco, F. A. (1994) · Critical Reviews in Oral Biology & Medicine · doi:10.1177/10454411940050030201 · Cited by 328
Bäckhed, F., Alsén, B., Roche, N., Ångström, J., von Euler, A., Breimer, M. E., Westerlund-Wikström, B., Teneberg, S., & Richter-Dahlfors, A. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m111640200 · Cited by 96
Metadata
- Authors
- Aronson, M., Medalia, O., Schori, L., Mirelman, D., Sharon, N., & Ofek, I.
- Venue
- Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1979-03-01
- Volume
- 139
- Issue
- 3
- Pages
- 329-332
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2161195329
- Cited by
- 325
- References
- 0
- FWCI
- 12.49
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Prevention of Colonization of the Urinary Tract of Mice with Escherichia coli by Blocking of Bacterial Adherence with Methyl -D-Mannopyranoside. https://app.cochat.ai/papers/10.1093/infdis/139.3.329
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- Aronson, M., Medalia, O., Schori, L., Mirelman, D., Sharon, N., & Ofek, I. (1979). Prevention of Colonization of the Urinary Tract of Mice with Escherichia coli by Blocking of Bacterial Adherence with Methyl -D-Mannopyranoside. Journal of Infectious Diseases. https://doi.org/10.1093/infdis/139.3.329
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
