The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Hepatitis C Virus Infection in an Area Hyperendemic for Hepatitis B and Chronic Liver Disease: The Taiwan Experience
Abstract
To assess the contribution of hepatitis C virus (HCV) in liver disease in Taiwan, antibody to HCV (anti-HCV) was studied by radioimmunoassay in 392 patients with chronic liver disease and in 440 healthy adults and 444 subjects at risk. The anti-HCV prevalence was 0.95% in 420 volunteer blood donors, 90% in 100 hemophiliacs, and 81% in 58 parenteral drug abusers. Anti-HCV was present in 6 (7.7%) of 78 hepatitis B surface antigen (HBsAg)-positive and 28 (65%) of 43 HBsAg-negative patients with chronic hepatitis, 3 (10%) of 31 HBsAg-positive and 13 (43%) of 30 HBsAg-negative cirrhotics, and 7 (17%) of 42 HBsAg-positive and 15 (63%) of 24 HBsAg-negative patients with hepatocellular carcinoma (HCC). An outbreak of non-A, non-B hepatitis revealed 18% of 57 patients to be positive for anti-HCV, and in 29 patients with posttransfusion hepatitis prospectively followed, 7 (24%) developed anti-HCV. Thus, HCV infection appears to play a relatively minor role in HBsAg-positive liver disease in Taiwan but is strongly associated with HBsAg-negative chronic liver disease and HCC. The infection is extremely common in hemophiliacs and parenteral drug abusers.
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Cites
Rotavirus gene structure and function.
Estes, M. K., & Cohen, J. (1989) · Microbiological Reviews · doi:10.1128/mmbr.53.4.410-449.1989 · Cited by 885
Cited by
Chang, M.-H., Chen, C.-J., Lai, M.-S., Hsu, H.-M., Wu, T.-C., Kong, M.-S., Liang, D.-C., Shau, W.-Y., & Chen, D.-S. (1997) · New England Journal of Medicine · doi:10.1056/nejm199706263362602 · Cited by 1,883
Self-citationDonato, F., Boffetta, P., & Puoti, M. (1998) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19980130)75:3<347::aid-ijc4>3.0.co;2-2 · Cited by 543
Razavi, H., Waked, I., Sarrazin, C., Myers, R. P., Idilman, R., Calinas, F., Vogel, W., Mendes Correa, M. C., Hézode, C., Lázaro, P., et al. (2014) · Journal of Viral Hepatitis · doi:10.1111/jvh.12248 · Cited by 477
Epidemiological characteristics and risk factors of hepatocellular carcinoma
CHEN, C., YU, M., & LIAW, Y. (1997) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.1997.tb00513.x · Cited by 470
Self-citationShih, C. M., Lo, S. J., Miyamura, T., Chen, S. Y., & Lee, Y. H. (1993) · Journal of Virology · doi:10.1128/jvi.67.10.5823-5832.1993 · Cited by 332
Metadata
- Authors
- Chen, D.-S., Kuo, G. C., Sung, J.-L., Lai, M.-Y., Sheu, J.-C., Chen, P.-J., Yang, P.-M., Hsu, H.-M., Chang, M.-H., Chen, C.-J., Hahn, L.-C., Choo, Q.-L., Wang, T.-H., & Houghton, M.
- Venue
- Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1990-10-01
- Volume
- 162
- Issue
- 4
- Pages
- 817-822
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2091419807
- Cited by
- 324
- References
- 1
- FWCI
- 16.97
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Hepatitis C Virus Infection in an Area Hyperendemic for Hepatitis B and Chronic Liver Disease: The Taiwan Experience. https://app.cochat.ai/papers/10.1093/infdis/162.4.817
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- Chen, D.-S., Kuo, G. C., Sung, J.-L., Lai, M.-Y., Sheu, J.-C., Chen, P.-J., Yang, P.-M., Hsu, H.-M., Chang, M.-H., Chen, C.-J., Hahn, L.-C., Choo, Q.-L., Wang, T.-H., & Houghton, M. (1990). Hepatitis C Virus Infection in an Area Hyperendemic for Hepatitis B and Chronic Liver Disease: The Taiwan Experience. Journal of Infectious Diseases. https://doi.org/10.1093/infdis/162.4.817
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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