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Human Herpesvirus 6 Infection in Normal Human Brain Tissue
Open accessAbstract
Mario Luppi, Patrizia Barozzi, Antonio Maiorana, Roberto Marasca, Giuseppe Torelli; Human Herpesvirus 6 Infection in Normal Human Brain Tissue, The Journal of I
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“Similar to all herpesviruses, HHV-6 causes a primary infection, usually during the first two-three years of life, after which it becomes dormant predominantly inside monocytes and macrophages [3,4,5].”
From Human Herpesvirus 6—A Rare Aetiologic Agent for CNS Infections in Immunocompetent Individuals or an Underestimation? (2024) · cites this paper as [3]
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Plaque-associated expression of human herpesvirus 6 in multiple sclerosis.
Challoner, P. B., Smith, K., Parker, J. D. J., MacLeod, D. L., Coulter, S. N., Rose, T., Schultz, E. R., Bennett, J. L., Garber, R. L., & Chang, M. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.16.7440 · Cited by 617
Update on Human Herpesvirus 6 Biology, Clinical Features, and Therapy
Bolle, L. D., Naesens, L. M. J., & Clercq, E. D. (2005) · Clinical Microbiology Reviews · doi:10.1128/cmr.18.1.217-245.2005 · Cited by 524
“It includes brain tissue (60, 110, 248), liver tissue (155, 186,”
BackgroundBraun, D. K., Dominguez, G., & Pellett, P. E. (1997) · Clinical Microbiology Reviews · doi:10.1128/cmr.10.3.521 · Cited by 492
“Consistent with this hypothesis, HHV-6-specific DNA was detected by PCR in over 80% of autopsy brain specimens, suggesting that the CNS of most people is persistently infected with HHV-6 (87, 329, 330).”
Soldan, S. S., Berti, R., Salem, N., Secchiero, P., Flamand, L., Calabresi, P. A., Brennan, M. B., Maloni, H. W., McFarland, H. F., Lin, H. C., et al. (1997) · Nature Medicine · doi:10.1038/nm1297-1394 · Cited by 445
Classification of HHV-6A and HHV-6B as distinct viruses
Ablashi, D. V., Agut, H., Álvarez‐Lafuente, R., Clark, D. A., Dewhurst, S., Luca, D. D., Flamand, L., Frenkel, N., Gallo, R. C., Gompels, U. A., et al. (2013) · Archives of Virology · doi:10.1007/s00705-013-1902-5 · Cited by 354
Self-citation
Metadata
- Authors
- Luppi, M., Barozzi, P., Maiorana, A., Marasca, R., & Torelli, G.
- Affiliations
- University of Modena and Reggio Emilia (IT)
- Corresponding author
- Torelli, G.
- Venue
- Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1994-04-01
- Volume
- 169
- Issue
- 4
- Pages
- 943-944
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2325138701
- Cited by
- 130
- References
- 0
- Citations by year
- 2026: 2 · 2024: 3 · 2023: 2 · 2022: 2 · 2021: 1 · 2020: 5 · 2019: 2 · 2018: 1 · 2017: 4 · 2016: 2 · 2015: 3 · 2014: 3 · 2013: 3 · 2012: 1
- FWCI
- 6.86
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- cc-by
- Locations
- The Journal of Infectious Diseases (publishedVersion)
- PubMed (publishedVersion)
- IRIS UNIMORE (University of Modena and Reggio Emilia) (submittedVersion, cc-by)
- Topics
- Health Sciences › Medicine › Epidemiology › Cytomegalovirus and herpesvirus research
- Health Sciences › Medicine › Oncology › Viral-associated cancers and disorders
- Health Sciences › Medicine › Infectious Diseases › Herpesvirus Infections and Treatments
- Keywords
- human herpesvirus 6, viral latency, neurotropism
- MeSH terms
- Base Sequence, Brain, Carrier State, DNA, Viral, Herpesviridae Infections, Humans, Molecular Sequence Data, Herpesvirus 6, Human, Polymerase Chain Reaction, DNA Primers
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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