The DOI matches its Crossref record; 84 of the 85 references it cites were found in a registry or an index.
Tuberculosis Diagnostics and Biomarkers: Needs, Challenges, Recent Advances, and Opportunities
Open accessAbstract
Tuberculosis is unique among the major infectious diseases in that it lacks accurate rapid point-of-care diagnostic tests. Failure to control the spread of tuberculosis is largely due to our inability to detect and treat all infectious cases of pulmonary tuberculosis in a timely fashion, allowing continued Mycobacterium tuberculosis transmission within communities. Currently recommended gold-standard diagnostic tests for tuberculosis are laboratory based, and multiple investigations may be necessary over a period of weeks or months before a diagnosis is made. Several new diagnostic tests have recently become available for detecting active tuberculosis disease, screening for latent M. tuberculosis infection, and identifying drug-resistant strains of M. tuberculosis. However, progress toward a robust point-of-care test has been limited, and novel biomarker discovery remains challenging. In the absence of effective prevention strategies, high rates of early case detection and subsequent cure are required for global tuberculosis control. Early case detection is dependent on test accuracy, accessibility, cost, and complexity, but also depends on the political will and funder investment to deliver optimal, sustainable care to those worst affected by the tuberculosis and human immunodeficiency virus epidemics. This review highlights unanswered questions, challenges, recent advances, unresolved operational and technical issues, needs, and opportunities related to tuberculosis diagnostics.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Second, availability issues, such as geographical constraints, resource shortages, or long waiting times, can cause significant diagnostic errors even when specific tests exist [189,190].”
From Toward Safer Diagnoses: A SEIPS-Based Narrative Review of Diagnostic Errors (2026) · cites this paper as [189]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Dye, C., Scheele, S., >Dolin, P., Pathania, V. S., Raviglione, M. C., & for the WHO Global Surveillance and Monitoring Project (1999) · JAMA · doi:10.1001/jama.282.7.677 · Cited by 2,955
Rapid Molecular Detection of Tuberculosis and Rifampin Resistance
Boehme, C. C., Nabeta, P., Hillemann, D., Nicol, M. P., Shenai, S., Krapp, F., Allen, J., Tahirli, R., Blakemore, R., Rustomjee, R., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0907847 · Cited by 2,309
(2012) · Choice Reviews Online · doi:10.5860/choice.49-6620 · Cited by 1,284
A systematic review of delay in the diagnosis and treatment of tuberculosis
Storla, D. G., Yimer, S. A., & Bjune, G. A. (2008) · BMC Public Health · doi:10.1186/1471-2458-8-15 · Cited by 1,023
Boehme, C. C., Nicol, M. P., Nabeta, P., Michael, J. S., Gotuzzo, E., Tahirli, R., Gler, M. T., Blakemore, R., Worodria, W. O., Gray, C. M., et al. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60438-8 · Cited by 1,007
Self-citationHelb, D., Jones, M., Story, E., Boehme, C., Wallace, E., Ho, K., Kop, J., Owens, M. R., Rodgers, R., Banada, P., et al. (2010) · Journal of Clinical Microbiology · doi:10.1128/jcm.01463-09 · Cited by 914
Lawn, S. D., & Zumla, A. I. (2011) · The Lancet · doi:10.1016/s0140-6736(10)62173-3 · Cited by 804
Self-citationNewsom, S. W. B. (2006) · Journal of Hospital Infection · doi:10.1016/j.jhin.2006.06.003 · Cited by 636
Steingart, K. R., Ng, V., Henry, M., Hopewell, P. C., Ramsay, A., Cunningham, J. A., Urbanczik, R., Perkins, M. D., Aziz, M. A., & Pai, M. (2006) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(06)70602-8 · Cited by 580
Diel, R., Goletti, D., Ferrara, G., Bothamley, G. H., Cirillo, D. M., Kampmann, B., Lange, C. G., Losi, M., Markova, R., Migliori, G. B., et al. (2010) · European Respiratory Journal · doi:10.1183/09031936.00115110 · Cited by 542
Self-citation
Research works printed but not linked: 10
- World Health Organization, 2011, WHO report. Global tuberculosis control
- World Health Organization, 2010, Multidrug and extensively drug-resistant TB (M/XDR-TB): 2010 global report on surveillance and response
- World Health Organization, 2011, Commercial serodiagnostic tests for diagnosis of tuberculosis: policy statement
- European Centre for Disease Prevention and Control, 2011, Use of interferon-gamma release assays in support of tuberculosis diagnosis
- World Health Organization, 2010, Use of interferon-γ release assays (IGRAs) in TB control in low and middle-income settings
- World Health Organization, 2011, Rapid implementation of the Xpert MTB/RIF diagnostic test: technical and operational “How-to”; practical considerations
- 2011, FIND. Performance of Xpert MTB/RIF version G4 assay. Geneva: Foundation for Innovative New Diagnostics
- World Health Organization, 2008, New laboratory diagnostic tools for tuberculosis control
- World Health Organization, 2009, Report of the 9th meeting: WHO strategic and technical advisory group for tuberculosis
- Treatment Action Group, 2009, 2009 report on tuberculosis research funding Trends, 2005–2008
Cited by
Sorted by citations
Clark, A. E., Kaleta, E. J., Arora, A., & Wolk, D. M. (2013) · Clinical Microbiology Reviews · doi:10.1128/cmr.00072-12 · Cited by 949
Advances in the development of new tuberculosis drugs and treatment regimens
Zumla, A. I., Nahid, P., & Cole, S. T. (2013) · Nature Reviews Drug Discovery · doi:10.1038/nrd4001 · Cited by 921
Self-citationZumla, A. I., Raviglione, M. C., Hafner, R., & von Reyn, C. F. (2013) · New England Journal of Medicine · doi:10.1056/nejmra1200894 · Cited by 699
Self-citationLawn, S. D., Mwaba, P., Bates, M., Piatek, A. S., Alexander, H. L., Marais, B. J., Cuevas, L. E., McHugh, T. D., Zijenah, L. S., Kapata, N., et al. (2013) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(13)70008-2 · Cited by 459
Self-citationProspects for Tuberculosis Elimination
Dye, C., Glaziou, P., Floyd, K., & Raviglione, M. C. (2012) · Annual Review of Public Health · doi:10.1146/annurev-publhealth-031912-114431 · Cited by 405
Scaling up interventions to achieve global tuberculosis control: progress and new developments
Raviglione, M. C., Marais, B. J., Floyd, K., Lönnroth, K., Getahun, H., Migliori, G. B., Harries, A. D., Nunn, P. P., Lienhardt, C., Graham, S., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)60727-2 · Cited by 334
Self-citationGraham, S. M., Ahmed, T., Amanullah, F., Browning, R., Cárdenas, V., Casenghi, M., Cuevas, L. E., Gale, M., Gie, R. P., Grzemska, M., et al. (2012) · The Journal of Infectious Diseases · doi:10.1093/infdis/jis008 · Cited by 326
Self-citationFunctional Signatures of Human CD4 and CD8 T Cell Responses to Mycobacterium tuberculosis
Prezzemolo, T., Guggino, G., Manna, M. P. L., Liberto, D. D., Dieli, F., & Caccamo, N. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00180 · Cited by 278
TUBERCULOSIS: EPIDEMIOLOGY AND CONTROL
Sulis, G., Roggi, A., Matteelli, A., & Raviglione, M. C. (2014) · Mediterranean Journal of Hematology and Infectious Diseases · doi:10.4084/mjhid.2014.070 · Cited by 203
WHO's 2013 global report on tuberculosis: successes, threats, and opportunities
Zumla, A. I., George, A., Sharma, V., Herbert, N., & Masham, B. S. (2013) · The Lancet · doi:10.1016/s0140-6736(13)62078-4 · Cited by 187
Self-citationThe heterogeneous evolution of multidrug-resistant Mycobacterium tuberculosis
Müller, B., Borrell, S., Rose, G., & Gagneux, S. (2012) · Trends in Genetics · doi:10.1016/j.tig.2012.11.005 · Cited by 185
Role of apoptosis and autophagy in tuberculosis
Lam, A., Prabhu, R., Groß, C., Riesenberg, L. A., Singh, V., & Aggarwal, S. (2017) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00162.2017 · Cited by 182
Zumla, A. I., Al‐Tawfiq, J. A., Enne, V. I., Kidd, M., Drosten, C., Breuer, J., Müller, M. A., Hui, D. S. C., Maeurer, M. J., Bates, M., et al. (2014) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(14)70827-8 · Cited by 175
Self-citationBates, M., O’Grady, J., Maeurer, M. J., Tembo, J. M., Chilukutu, L., Chabala, C., Kasonde, R., Mulota, P., Mzyece, J., Chomba, M., et al. (2012) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(12)70245-1 · Cited by 152
Self-citationZhang, X., Guo, J., Fan, S., Li, Y., Wei, L., Yang, X., Jiang, T., Chen, Z., Wang, C., Liu, J., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0081076 · Cited by 140
Extensively drug-resistant tuberculosis: epidemiology and management
Matteelli, A., Roggi, A., & Carvalho, A. C. C. (2014) · Clinical Epidemiology · doi:10.2147/clep.s35839 · Cited by 124
Stopping tuberculosis: a biosocial model for sustainable development
Ortblad, K. F., Salomon, J. A., Bärnighausen, T., & Atun, R. A. (2015) · The Lancet · doi:10.1016/s0140-6736(15)00324-4 · Cited by 130
Self-citationBalada-Llasat, J.-M., Kamboj, K. K., & Pancholi, P. (2013) · Journal of Clinical Microbiology · doi:10.1128/jcm.00819-13 · Cited by 99
miRNA Signatures in Sera of Patients with Active Pulmonary Tuberculosis
Miotto, P., Mwangoka, G., Valente, I. C., Norbis, L., Sotgiu, G., Bosu, R., Ambrosi, A., Codecasa, L. R., Goletti, D., Matteelli, A., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0080149 · Cited by 85
Xu, D., Deng, D., Li, X., Wei, L., Li, Y., Yang, X., Yu, W., Wang, C., Jiang, T., Li, Z., et al. (2013) · PROTEOMICS · doi:10.1002/pmic.201300383 · Cited by 75
High mortality among tuberculosis patients on treatment in Nigeria: a retrospective cohort study
Adamu, A. L., Gadanya, M. A., Abubakar, I. S., Jibo, A. M., Bello, M. M., Gajida, A. U., Babashani, M., & Abubakar, I. (2017) · BMC Infectious Diseases · doi:10.1186/s12879-017-2249-4 · Cited by 74
Self-citationA metabolic biosignature of early response to anti-tuberculosis treatment
Mahapatra, S., Hess, A. M., Johnson, J. L., Eisenach, K. D., DeGroote, M. A., Gitta, P., Joloba, M. L., Kaplan, G., Walzl, G., Boom, W. H., et al. (2014) · BMC Infectious Diseases · doi:10.1186/1471-2334-14-53 · Cited by 73
Emerging technologies in point-of-care molecular diagnostics for resource-limited settings
Peeling, R. W. W., & McNerney, R. (2014) · Expert Review of Molecular Diagnostics · doi:10.1586/14737159.2014.915748 · Cited by 74
Self-citationKaraballi, R. A., Nel, A. J. M., Krishnan, S., Blackburn, J. M., & Brosseau, C. L. (2015) · Physical Chemistry Chemical Physics · doi:10.1039/c4cp05077k · Cited by 68
Li, H., Gao, X., Luò, T., Wu, J., Sun, G. Z., Liu, Q., Jiang, Y. Z., Zhang, Y., Mei, J., & Gao, Q. (2014) · Emerging Microbes & Infections · doi:10.1038/emi.2014.21 · Cited by 67
An acoustofluidic sputum liquefier
Huang, P., Ren, L., Nama, N., Li, S., Li, P., Yao, X., Cuento, R. A., Wei, C., Chen, Y., Xie, Y., et al. (2015) · Lab on a Chip · doi:10.1039/c5lc00539f · Cited by 66
Diagnosing tuberculous meningitis – have we made any progress?
Ho, J., Marais, B. J., Gilbert, G. L., & Ralph, A. P. (2013) · Tropical Medicine & International Health · doi:10.1111/tmi.12099 · Cited by 65
Self-citationTuberculosis: lights and shadows in the current diagnostic landscape.
Norbis, L., Miotto, P., Alagna, R., & Cirillo, D. M. (2013) · PubMed · Cited by 62
Al‐Anazi, K. A., Al-Jasser, A. M., & Alsaleh, K. A. (2014) · Frontiers in Oncology · doi:10.3389/fonc.2014.00231 · Cited by 56
Ng, B. Y. C., Xiao, W., West, N. P., Wee, E. J. H., Wang, Y., & Trau, M. (2015) · Analytical Chemistry · doi:10.1021/acs.analchem.5b03121 · Cited by 58
Which New Diagnostics for Tuberculosis, and When?
Cobelens, F. G. J., van den Hof, S., Pai, M., Squire, S. B., Ramsay, A., & Kimerling, M. E. (2012) · The Journal of Infectious Diseases · doi:10.1093/infdis/jis188 · Cited by 55
Self-citationWorld TB Day 2014: finding the missing 3 million
Herbert, N., George, A., Ilton, B. M. O., Sharma, V., Oliver, M., Oxley, A., Raviglione, M. C., & Zumla, A. I. (2014) · The Lancet · doi:10.1016/s0140-6736(14)60422-0 · Cited by 52
Self-citationHost Targeted Activity of Pyrazinamide in Mycobacterium tuberculosis Infection
Manca, C., Koo, M.-S., Peixoto, B., Fallows, D., Kaplan, G., & Subbian, S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0074082 · Cited by 49
Developing Biosensors in Developing Countries: South Africa as a Case Study
Fogel, R., & Limson, J. L. (2016) · Biosensors · doi:10.3390/bios6010005 · Cited by 49
Mycobacterial Skin and Soft Tissue Infection
Wang, S., & Pancholi, P. (2014) · Current Infectious Disease Reports · doi:10.1007/s11908-014-0438-5 · Cited by 48
Biomarker detection of global infectious diseases based on magnetic particles.
Carinelli, S., Martí, M., Alegret, S., & Pividori, M. (2015) · New Biotechnology · doi:10.1016/j.nbt.2015.04.002 · Cited by 45
Zou, F., Wang, X., Qi, F., Koh, K., Lee, J., Zhou, H., & Chen, H. (2017) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2017.04.162 · Cited by 46
The discovery and identification of a candidate proteomic biomarker of active tuberculosis
Liu, J., Jiang, T., Wei, L., Yang, X., Wang, C., Zhang, X., Xu, D., Chen, Z., Yang, F., & Li, J. (2013) · BMC Infectious Diseases · doi:10.1186/1471-2334-13-506 · Cited by 45
A multi-arm multi-stage clinical trial design for binary outcomes with application to tuberculosis
Bratton, D. J., Phillips, P. P. J., & Parmar, M. (2013) · BMC Medical Research Methodology · doi:10.1186/1471-2288-13-139 · Cited by 46
Zumla, A. I., & Maeurer, M. J. (2015) · Clinical Infectious Diseases · doi:10.1093/cid/civ631 · Cited by 45
Self-citationPathogen-derived biomarkers for active tuberculosis diagnosis
Tucci, P., González‐Sapienza, G., & Marı́n, M. (2014) · Frontiers in Microbiology · doi:10.3389/fmicb.2014.00549 · Cited by 43
Ng, B. Y. C., Wee, E. J. H., West, N. P., & Trau, M. (2015) · Scientific Reports · doi:10.1038/srep15027 · Cited by 42
Bakhori, N. M., Yusof, N. A., Abdullah, J., Wasoh, H., Rahman, S. K. A., & Rahman, S. F. A. (2019) · Materials · doi:10.3390/ma13010149 · Cited by 44
Corbett, E. L., & MacPherson, P. (2013) · The International Journal of Tuberculosis and Lung Disease · doi:10.5588/ijtld.13.0117 · Cited by 43
MicroRNAs as diagnostic biomarkers for Tuberculosis: A systematic review and meta- analysis
Daniel, E. A., Sathiyamani, B., Thiruvengadam, K., Vivekanandan, S., Vembuli, H., & Hanna, L. E. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.954396 · Cited by 41
Innovative clinical trial designs to rationalize TB vaccine development
Ellis, R. D., Hatherill, M., Tait, D. R., Snowden, M. A., Churchyard, G., Hanekom, W. A., Evans, T., & Ginsberg, A. M. (2015) · Tuberculosis · doi:10.1016/j.tube.2015.02.036 · Cited by 41
Secretome analysis of Trypanosoma cruzi by proteomics studies
Brossas, J., Gulin, J. E. N., Bisio, M. M. C., Chapelle, M., Marinach, C., Bordessoulles, M., Ruiz, G. P., Vion, J., Paris, L., Altcheh, J., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0185504 · Cited by 41
Salomon, J. J., Galeron, P., Schulte, N. E., Morow, P. R., Severynse-Stevens, D., Huwer, H., Schneider‐Daum, N., Lehr, C., Hickey, A. J., & Ehrhardt, C. (2013) · Therapeutic Delivery · doi:10.4155/tde.13.62 · Cited by 38
Ng, B. Y. C., Wee, E. J. H., Woods, K., Anderson, W., Antaw, F., Tsang, H., West, N., & Trau, M. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.7b01685 · Cited by 23
Acoustofluidic Transfer of Inflammatory Cells from Human Sputum Samples
Li, S., Ren, L., Huang, P., Yao, X., Cuento, R. A., McCoy, J. P., Cameron, C. E., Levine, S. J., & Huang, T. J. (2016) · Analytical Chemistry · doi:10.1021/acs.analchem.5b03383 · Cited by 36
Mathematical Modelling and Tuberculosis: Advances in Diagnostics and Novel Therapies
Zwerling, A. A., Shrestha, S., & Dowdy, D. W. (2015) · Advances in Medicine · doi:10.1155/2015/907267 · Cited by 35
Kim, J., Lee, J., Lee, K.-I., Park, T. J., Kim, H., & Lee, J. (2012) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2012.11.011 · Cited by 34
Transcriptomics in Human Challenge Models
Barton, A., Hill, J. W., Pollard, A. J., & Blohmke, C. J. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01839 · Cited by 33
Bates, M., Ahmed, Y., Chilukutu, L., Tembo, J. M., Cheelo, B., Sinyangwe, S. S., Kapata, N., Maeurer, M. J., O’Grady, J., Mwaba, P., et al. (2013) · Tropical Medicine & International Health · doi:10.1111/tmi.12145 · Cited by 32
Self-citationAdu-Gyamfi, C. G., Savulescu, D. M., George, J. A., & Suchard, M. S. (2019) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2019.00372 · Cited by 33
Curving Tuberculosis: Current Trends and Future Needs
Rojano, B., Caminero, J. A., & Hayek, M. (2019) · Annals of Global Health · doi:10.5334/aogh.2415 · Cited by 31
Mutavhatsindi, H., van der Spuy, G. D., Malherbe, S. T., Sutherland, J. S., Geluk, A., Mayanja‐Kizza, H., Crampin, A. C., Kassa, D., Howe, R., Mihret, A., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.607827 · Cited by 31
Pan, L., Liu, F., Zhang, J.-L., Li, J., Jia, H., Huang, M., Liu, X., Chen, W., Ding, Z., Wang, Y., et al. (2019) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2019.00323 · Cited by 30
Pollock, N. R., Macovei, L., Kanunfre, K. A., Dhiman, R. K., Restrepo, B. I., Zarate, I., Pino, P. A., Mora-Guzmán, F., Fujiwara, R. T., Michel, G., et al. (2013) · Journal of Clinical Microbiology · doi:10.1128/jcm.03192-12 · Cited by 30
Gastric aspiration is not necessary for the diagnosis of pulmonary tuberculosis
Bonnave, P.-E., Raoult, D., & Drancourt, M. (2012) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-012-1776-6 · Cited by 29
Host Genomics and Control of Tuberculosis Infection
Cobat, A., Orlova, M., Barrera, L. F., & Schurr, E. (2013) · Public Health Genomics · doi:10.1159/000341499 · Cited by 29
Zwerling, A. A., White, R. G., Vassall, A., Cohen, T., Dowdy, D. W., & Houben, R. M. G. J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0110558 · Cited by 28
The Bandim TBscore – reliability, further development, and evaluation of potential uses
Rudolf, F. (2014) · Global Health Action · doi:10.3402/gha.v7.24303 · Cited by 27
Patel, K., Nagel, M., Wesolowski, M., Dees, S., Rivera‐Milla, E., Geldmacher, C., Dheda, K. U. J., Höelscher, M., & Labugger, I. (2017) · Journal of Molecular Diagnostics · doi:10.1016/j.jmoldx.2017.11.005 · Cited by 28
Tuberculosis: a focused review for the emergency medicine clinician
Long, B., Liang, S. Y., Koyfman, A., & Gottlieb, M. A. (2019) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2019.12.040 · Cited by 27
Yang, Y., Mu, J., Chen, G., ZHAN, Y., Zhong, J., Wei, Y.-D., Cheng, K., Qin, B. Y., You, H., & Xie, P. (2015) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2015.2131 · Cited by 26
Li, H., Ren, W., Liang, Q., Zhang, X., Li, Q., Shang, Y., Ma, L., Li, S., & Pang, Y. (2023) · QJM · doi:10.1093/qjmed/hcad214 · Cited by 25
De, P., Shi, L., Boot, C. M., Ordway, D. J., McNeil, M., & Chatterjee, D. (2019) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.9b00355 · Cited by 25
Kirwan, D. E., Cárdenas, M. K., & Gilman, R. H. (2012) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2012.12-0107 · Cited by 24
Blair, E. O., Hannah, S., Vezza, V. J., Avcı, H., Kocagöz, T., Hoskisson, P. A., Güzel, F. D., & Corrigan, D. K. (2020) · Sensors and Actuators Reports · doi:10.1016/j.snr.2020.100008 · Cited by 24
Diagnosis of pulmonary tuberculosis using Ziehl–Neelsen stain or cold staining techniques?
Abdelaziz, M. M., Bakr, W., Hussien, S. M., & Amine, A. (2016) · Journal of the Egyptian Public Health Association · doi:10.1097/01.epx.0000481358.12903.af · Cited by 23
Biosensors; nanomaterial-based methods in diagnosing of Mycobacterium tuberculosis
Mobed, A., Darvishi, M., Kohansal, F., Dehfooli, F. M., Alipourfard, I., Tahavvori, A., & Ghazi, F. (2023) · Journal of Clinical Tuberculosis and Other Mycobacterial Diseases · doi:10.1016/j.jctube.2023.100412 · Cited by 22
Bates, M., & Zumla, A. I. (2016) · Expert Review of Molecular Diagnostics · doi:10.1586/14737159.2016.1139457 · Cited by 21
Self-citationMeyer, A. J., Ochom, E., Turimumahoro, P., Byanyima, P., Sanyu, I., Lalitha, R., Kaswabuli, S., Andama, A. O., Walter, N. D., Katamba, A., et al. (2020) · Journal of Clinical Microbiology · doi:10.1128/jcm.02162-20 · Cited by 21
Axelsson‐Robertson, R., Ju, J. H., Kim, H., Zumla, A. I., & Maeurer, M. J. (2015) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2014.12.017 · Cited by 20
Self-citationPast and Present Approaches to Diagnosis of Active Pulmonary Tuberculosis
Namuganga, A. R., Chegou, N. N., & Mayanja‐Kizza, H. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.709793 · Cited by 19
Simner, P. J., Buckwalter, S. P., Uhl, J. R., & Wengenack, N. L. (2013) · Journal of Clinical Microbiology · doi:10.1128/jcm.01408-13 · Cited by 19
Zahoor, D., Bhat, M., Kanth, F., & Farhana, A. (2019) · International Journal of Contemporary Medical Research [IJCMR] · doi:10.21276/ijcmr.2019.6.6.17 · Cited by 19
Li, Q., Ren, W., Yuan, J., Guo, H., Shang, Y., Wang, W., Pan, J., Gao, M., & Pang, Y. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.904308 · Cited by 17
Diagnostic performance of interferon-γ release assay for lymph node tuberculosis
Jia, H., Pan, L., Du, B., Sun, Q., Wei, R., Xing, A., Du, F., Sun, H., & Zhang, Z. (2016) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2016.02.001 · Cited by 17
A High Fundamental Frequency (HFF)-based QCM Immunosensor for Tuberculosis Detection
Montoya, A., March, C., Montagut-Ferizzola, Y. J., Moreno, M., Manclús, J. J., Arnau, A., Jiménez, Y., Jaramillo, M., Marín, P. M., & Torres, R. (2016) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026617666161104105210 · Cited by 17
Cost analysis of rapid diagnostics for drug-resistant tuberculosis
Groessl, E. J., Ganiats, T. G., Hillery, N., Trollip, A. P., Jackson, R. L., Catanzaro, D. G., Rodwell, T. C., Garfein, R. S., Rodrigues, C. S., Crudu, V., et al. (2018) · BMC Infectious Diseases · doi:10.1186/s12879-018-3013-0 · Cited by 17
Pang, Y., Li, Q., Ou, X., Sohn, H., Zhang, Z., Li, J., Xia, H., Kam, K. M., O’Brien, R. J., Chi, J., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0069267 · Cited by 16
Tiwari, D., Haque, S., Tiwari, R. P., Jawed, A., Govender, T., & Kruger, H. G. (2015) · Journal of Microbiology Immunology and Infection · doi:10.1016/j.jmii.2015.05.014 · Cited by 16
Álvarez, Á. H. (2021) · Microbiological Research · doi:10.1016/j.micres.2021.126853 · Cited by 15
Kyaw, S. P., Hanthamrongwit, J., Jangpatarapongsa, K., Khaenam, P., & Leepiyasakulchai, C. (2018) · RSC Advances · doi:10.1039/c8ra06599c · Cited by 15
Zhao, Y. X., Li, G., Sun, C., Li, C., Wang, X., Liu, H., Zhang, P., Zhao, X., Wang, X., Jiang, Y., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0143444 · Cited by 14
Tuberculosis: Integrated Studies for a Complex Disease 2050
Rezaei, N., Hosseini, N., Saghazadeh, A., Fateh, A., Duse, A. G., Ahmad, A., Braley, A. E., Tahta, A., Kamboj, A., Khan, A. H., et al. (2023) · Integrated science · doi:10.1007/978-3-031-15955-8_51 · Cited by 13
Javed, S., Marsay, L., Wareham, A., Lewandowski, K. S., Williams, A., Dennis, M. J., Sharpe, S. A., Vipond, R., Silman, N. J., Ball, G., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0154320 · Cited by 13
Pan, L., Liu, F., Zhang, J., Yang, X., Zheng, S., Li, J., Jia, H., Chen, X., Gao, M., & Zhang, Z. (2017) · BioMed Research International · doi:10.1155/2017/8198505 · Cited by 13
BCG vaccination for bovine tuberculosis; conclusions from the Jerusalem One Health workshop
Marais, B. J., Buddle, B. M., de Klerk‐Lorist, L., Nguipdop‐Djomo, P., Quinn, F. D., & Greenblatt, C. L. (2018) · Transboundary and Emerging Diseases · doi:10.1111/tbed.13089 · Cited by 15
Self-citationEvaluation of interferon-γ release assay in the diagnosis of osteoarticular tuberculosis
Jia, H., Pan, L., Qin, S., Liu, F., Du, F., Lan, T., Zhang, X., Wei, R., Du, B., Liu, Z., et al. (2013) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2013.03.030 · Cited by 13
Mass spectrometry applied to the identification ofMycobacterium tuberculosisand biomarker discovery
López‐Hernández, Y., Patiño-Rodríguez, O., García-Orta, S. T., & Pinos‐Rodríguez, J. M. (2016) · Journal of Applied Microbiology · doi:10.1111/jam.13323 · Cited by 13
Molecular Approaches and Biomarkers for Detection of Mycobacterium tuberculosis
Luo, R. F., & Banaei, N. (2013) · Clinics in Laboratory Medicine · doi:10.1016/j.cll.2013.03.012 · Cited by 12
Kim, H., Kim, S., Jung, J. H., Kim, M. J., Kim, H., Shin, S. H., Chong, Y. P., Kim, Y., Lee, S., Choi, S., et al. (2020) · Journal of Infection · doi:10.1016/j.jinf.2020.06.070 · Cited by 12
Advancing Tuberculosis Chemotherapy: Targeted Nanomedicines for the Mycobacterium TB Granuloma
Singh, S. R., Makatini, M. M., Marimuthu, T., & Choonara, Y. E. (2025) · Small · doi:10.1002/smll.202506381 · Cited by 12
Rotake, D. R., Zalke, J. B., Gechode, H. V., Peshkar, S. M., & Singh, S. G. (2024) · Microchimica Acta · doi:10.1007/s00604-024-06780-9 · Cited by 11
Jeremiah, K., Lyimo, E., Ritz, C., PrayGod, G., Rutkowski, K. T., Korsholm, K. S., Rühwald, M., Tait, D. R., Grewal, H. M. S., & Faurholt‐Jepsen, D. (2021) · PLoS ONE · doi:10.1371/journal.pone.0252808 · Cited by 11
MiR-27a-3p and miR-30b-5p inhibited-vitamin D receptor involved in the progression of tuberculosis
Xiao, M., Yang, S., Zhou, A., Li, T., Liu, J., Chen, Y., Luo, Y., Qian, C., Yang, F., Tang, B., et al. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.1020542 · Cited by 11
Battaglioli, T., Rintiswati, N., Martin, A., Palupi, K. R., Bernaerts, G., Dwihardiani, B., Ahmad, R. A., Matthys, F., Mahendradhata, Y., & der Stuyft, P. V. (2013) · Clinical Microbiology and Infection · doi:10.1111/1469-0691.12265 · Cited by 11
Metadata
- Authors
- McNerney, R., Maeurer, M., Abubakar, I., Marais, B., Mchugh, T. D., Ford, N., Weyer, K., Lawn, S., Grobusch, M. P., Memish, Z., Squire, S. B., Pantaleo, G., Chakaya, J., Casenghi, M., Migliori, G.-B., Mwaba, P., Zijenah, L., Hoelscher, M., Cox, H., Swaminathan, S., Kim, P. S., Schito, M., Harari, A., Bates, M., Schwank, S., O’Grady, J., Pletschette, M., Ditui, L., Atun, R., & Zumla, A.
- Affiliations
- London School of Hygiene & Tropical Medicine (GB)
- Karolinska Institutet (SE)
- University of East Anglia (GB)
- The University of Sydney (AU)
- University College London (GB)
- Médecins Sans Frontières (ZA)
- World Health Organization (CH)
- University of Cape Town (ZA)
- Amsterdam UMC Location University of Amsterdam (NL)
- Alfaisal University (SA)
- Liverpool School of Tropical Medicine (GB)
- Centre Hospitalier Universitaire Vaudois (CH)
- Kenya Medical Research Institute (KE)
- Ministry of Health (ZM)
- University of Zimbabwe (ZW)
- National Institute of Research in Tuberculosis (IN)
- National Institutes of Health (US)
- Henry M. Jackson Foundation (US)
- University of Zambia (ZM)
- European Commission (BE)
- Global Fund to Fight AIDS, Tuberculosis and Malaria (CH)
- Corresponding author
- McNerney, Ruth
- ORCID
- McNerney, Ruth
- Maeurer, Markus
- Abubakar, Ibrahim
- Marais, Ben
- Mchugh, Timothy D.
- Ford, Nathan
- Grobusch, Martin P.
- Memish, Ziad
- Squire, S. Bertel
- Pantaleo, Giuseppe
- Chakaya, Jeremiah
- Casenghi, Martina
- Mwaba, Peter
- Zijenah, Lynn
- Cox, Helen
- Swaminathan, Soumya
- Kim, Peter S.
- Schito, Marco
- Harari, Alexandre
- Bates, Matthew
- O’Grady, Justin
- Atun, Rifat
- Zumla, Alimuddin
- Venue
- The Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-05-15
- Volume
- 205
- Issue
- suppl_2
- Pages
- S147-S158
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2145481449
- Cited by
- 191
- References
- 85
- Citations by year
- 2026: 4 · 2025: 12 · 2024: 4 · 2023: 8 · 2022: 9 · 2021: 9 · 2020: 5 · 2019: 12 · 2018: 7 · 2017: 13 · 2016: 16 · 2015: 23 · 2014: 21 · 2013: 36 · 2012: 12
- FWCI
- 3.67
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- other-oa
- Locations
- The Journal of Infectious Diseases (publishedVersion, other-oa)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion)
- SERVAL (Université de Lausanne) (publishedVersion, other-oa)
- NIRT Institutional Scholarship Repository (National Institute of Research in Tuberculosis) (acceptedVersion)
- reroDoc Digital Library (submittedVersion)
- IRIS (submittedVersion, other-oa)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- LSTM Online Archive (Liverpool School of Tropical Medicine) (submittedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Medecins Sans Frontieres Field Research (Medecins Sans Frontieres) (submittedVersion)
- Figshare (submittedVersion, cc-by)
- UEA Digital Repository (University of East Anglia) (submittedVersion)
- Funders
- University College London
- UBS Optimus Foundation
- University College London Hospitals NHS Foundation Trust
- Medical Research Council
- European and Developing Countries Clinical Trials Partnership
- Topics
- Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
- Health Sciences › Medicine › Infectious Diseases › Infectious Diseases and Tuberculosis
- Health Sciences › Medicine › Infectious Diseases › Diagnosis and treatment of tuberculosis
- Keywords
- tuberculosis diagnosis, Mycobacterium tuberculosis, biomarkers, point-of-care testing, latent tuberculosis infection, drug-resistant tuberculosis, early case detection, tuberculosis control
- MeSH terms
- Antitubercular Agents, Bacteriological Techniques, Humans, Tuberculosis, Biomarkers, Drug Resistance, Bacterial
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
