IL-6 in inflammation, autoimmunity and cancer

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8. Inflammatory bone marrow signaling in pediatric acute myeloid leukemia distinguishes patients with poor outcomes
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10. Ovotransferrin Inhibits TNF-α Induced Inflammatory Response in Gastric Epithelial Cells via MAPK and NF-κB Pathway
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14. Impact of STAT-signaling pathway on cancer-associated fibroblasts in colorectal cancer and its role in immunosuppression
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15. Evolution of a bispecific G-quadruplex-forming circular aptamer to block IL-6/sIL-6R interaction for inflammation inhibition
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16. Portulaca oleracea L. polysaccharide ameliorates ulcerative colitis by regulating the immune system and gut microbiota
    Yang Yang, Xiechen Zhou, Guiyan Jia, Hui Zhao, Yan Li, Junyang Cao, Zijian Guan, Rui Zhao · 2024 · Food Bioscience
17. E2F1-induced autocrine IL-6 inflammatory loop mediates cancer-immune crosstalk that predicts T cell phenotype switching and therapeutic responsiveness
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18. A Snapshot of Cytokine Dynamics: A Fine Balance Between Health and Disease
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19. Decoy oligonucleotides targeting NF-κB: a promising therapeutic approach for inflammatory diseases
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20. Research Progress of Plasma Cell Mastitis
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21. Tumor Microenvironment, Inflammation, and Inflammatory Prognostic Indices in Diffuse Large B-Cell Lymphomas: A Narrative Review
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22. Modulation of IL-6 Expression by KLF4-Mediated Transactivation and PCAF-Mediated Acetylation in Sublytic C5b-9-Induced Rat Glomerular Mesangial Cells
    Xia Lu, Yu Liu, Zhiwei Zhang · 2022 · Frontiers in Immunology
23. 4-Hydroxyphenyllactic Acid in Cerebrospinal Fluid as a Possible Marker of Post-Neurosurgical Meningitis: Retrospective Study
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24. Vitex trifolia L. modulates inflammatory mediators via down-regulation of the NF-κB signaling pathway in carrageenan-induced acute inflammation in experimental rats
    Parvathi Annamalai, E. Berla Thangam · 2022 · Journal of Ethnopharmacology
25. Blood immunological profile of abdominal aortic aneurysm based on autoimmune injury
    Haotian Huanggu, Dan Yang, Yuehong Zheng · 2022 · Autoimmunity Reviews
26. Interleukins, Chemokines, and Tumor Necrosis Factor Superfamily Ligands in the Pathogenesis of West Nile Virus Infection
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27. RETRACTED ARTICLE: Loteprednol-Loaded Nanoformulations for Corneal Delivery by Quality-by-Design Concepts: Optimization, Characterization, and Anti-inflammatory Activity
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28. Effects of berberine and barberry on selected inflammatory biomarkers in adults: A systematic review and dose–response meta‐analysis of randomized clinical trials
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29. Recent Advances in Biomimetic Drug Delivery for Rheumatoid Arthritis Treatment
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30. The role and therapeutic implication of endoplasmic reticulum stress in inflammatory cancer transformation.
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31. Updated insight into the role of Th2-associated immunity in systemic lupus erythematosus
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32. Water Extract of Chrysanthemum indicum L. Flower Inhibits Capsaicin-Induced Systemic Low-Grade Inflammation by Modulating Gut Microbiota and Short-Chain Fatty Acids
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33. Bioactive secondary metabolites in sea cucumbers and their potential to use in the functional food industry
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34. Curcumin-dependent phenotypic transformation of microglia mediates resistance to pseudorabies-induced encephalitis
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35. Serum Cytokine Profiles in Patients with Rheumatoid Arthritis Before and After Treatment with Methotrexate
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36. Schinus terebinthifolius Raddi (Brazilian pepper) leaves extract: in vitro and in vivo evidence of anti-inflammatory and antioxidant properties
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37. Systems Biology and Cytokines Potential Role in Lung Cancer Immunotherapy Targeting Autophagic Axis
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38. A decade of USFDA-approved small molecules as anti-inflammatory agents: Recent trends and Commentaries on the “industrial” perspective
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39. Mapping of the gene network that regulates glycan clock of ageing
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40. Ginsenosides and Tumors: A Comprehensive and Visualized Analysis of Research Hotspots and Antitumor Mechanisms
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41. Autoimmune response after SARS-CoV-2 infection and SARS-CoV-2 vaccines
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42. Genetic Variant rs1800795 (G>C) in the Interleukin 6 (IL6) Gene and Susceptibility to Coronary Artery Diseases, Type 2 Diabetes, Acute Pancreatitis, Rheumatoid Arthritis, and Bronchial Asthma in Asians: A Comprehensive Meta-Analysis Based on 30154 Subjects
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43. The Effects of Psilocybin on Lipopolysaccharide-Induced Inflammation in THP-1 Human Macrophages
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44. Cytokines and chemokines in patients with chronic inflammatory demyelinating polyradiculoneuropathy and multifocal motor neuropathy: A systematic review
    Claudia Cutellé, Alberto De Lorenzo, Pietro Emiliano Doneddu · 2024 · Journal of the Peripheral Nervous System
45. Mesenchymal stem cells in autoimmune disease: A systematic review and meta-analysis of pre-clinical studies
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46. Revolutionizing type 1 diabetes management: Exploring oral insulin and adjunctive treatments
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47. Berberine Inhibits Breast Cancer Stem Cell Development and Decreases Inflammation: Involvement of miRNAs and IL-6
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48. Innovative Multitarget Organoselenium Hybrids With Apoptotic and Anti‐Inflammatory Properties Acting as JAK1/STAT3 Suppressors
    Saad Shaaban, Aya Yaseen Mahmood Alabdali, Mai H. A. Mousa, Hussein Ba‐Ghazal, Yasair Suliman Al-Faiyz, Ibrahim Elghamry, Hanan A. Althikrallah, Arwa Omar Al Khatib, Mohamed A. Alaasar, Ahmed Ali Al-Karmalawy · 2025 · Drug Development Research
49. Spatially hierarchical nano-architecture for real time detection of Interleukin-8 cancer biomarker
    Sawsen Azzouzi, Mounir Ben Ali, Francesca Giuseppa Bellagambi · 2022 · Talanta
50. Protective effects of lavender oil on sepsis-induced acute lung injury via regulation of the NF-κB pathway
    Qian Xie, Yi Wang, Guoliang Zou · 2022 · Pharmaceutical Biology
51. IL-6/IL-10 mRNA expression ratio in tumor tissues predicts prognosis in gastric cancer patients without distant metastasis
    Li Zhou, Chuangang Tang, Xiaoxin Li, Fang Feng · 2022 · Scientific Reports
52. Neurological mechanism-based analysis of the role and characteristics of physical activity in the improvement of depressive symptoms
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53. Toxicity of nanoplastics: machine learning combined with meta-analysis
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54. Unravelling Immunity: Understanding Inflammatory Pathways as Key Players in Immune Response and Disease Progression
    Abhishek Ghara, Gurubasavaraja Swamy Purawarga Matada, Roshan Kumar Sah, Sneha S, Sophia S. Boneka, Arghya Paik, Subhajit Majumder, Payel Pramanick, Basavaraj Metikurki · 2025 · Current Molecular Biology Reports
55. Revolutionizing rheumatoid arthritis therapy: the potential of lipid nanocarriers
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56. Advancing Early Detection of Osteoarthritis Through Biomarker Profiling and Predictive Modelling: A Review
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57. Peripheral–central immune interactions in Parkinson’s disease: insights into innate and adaptive immunity
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58. IL ‐6 upregulates the expression of IL‐6R through the JAK2 / STAT3 signalling pathway to promote progression of hepatocellular carcinoma
    Li Song, Ruyue Xu, Wenpeng Cai, Jiaojiao Liang, Niandie Cao, Jiafeng Gao, Xiaolong Tang · 2023 · Scandinavian Journal of Immunology
59. Rac and Cdc42 inhibitors reduce macrophage function in breast cancer preclinical models
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60. Knowledge mapping of COVID-19 and autoimmune diseases: a visual and bibliometric analysis
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61. A Comprehensive Overview of Organ Inflammatory Responses: Genesis, Possible Mechanisms, and Mediators of Inflammation
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62. Single-cell RNA sequencing analysis of vestibular schwannoma reveals functionally distinct macrophage subsets
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63. Monoacylglycerol lipase blockades the senescence-associated secretory phenotype by interfering with NF-κB activation and promotes docetaxel efficacy in prostate cancer
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65. Elevated IL-6 Expression in Autologous Adipose-Derived Stem Cells Regulates RANKL Mediated Inflammation in Osteoarthritis
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66. The Role of Chronic Inflammation in Pediatric Cancer
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67. From Infection to Tumor: Exploring the Therapeutic Potential of Ciprofloxacin Derivatives as Anticancer Agents
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68. Nitrogen, Oxygen, and Sulphur Heterocycles as Potent Anti‐Inflammatory Agents: Insight Into the Synthetic Routes
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69. The mechanistic study of quercetin in the treatment of alcoholic brain injury via the JNK/P38 MAPK signaling pathway
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70. Interactions Between Specific Immune Status of Pregnant Women and SARS-CoV-2 Infection
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71. RETRACTED: Glycine Nano-Selenium Enhances Immunoglobulin and Cytokine Production in Mice Immunized with H9N2 Avian Influenza Virus Vaccine
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72. The pathogenesis of anti-signal recognition particle necrotizing myopathy: A Review
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73. Point of care diagnosis of dry eye disease with a sensitive immunoassay for dual biomarker detection
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74. Crosstalk between cancer stem cells and the tumor microenvironment drives progression of premalignant oral epithelium
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75. A narrative review on the anti-inflammatory efficacy of Bougainvillea spectabilis Willd. and its various applications
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76. Development and Characterization of Inula britannica Extract-Loaded Liposomes: Potential as Anti-Inflammatory Functional Food Ingredients
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77. γ-Secretase Inhibitor Potentiates the Activity of Suberoylanilide Hydroxamic Acid by Inhibiting Its Ability to Induce Epithelial to Mesenchymal Transition and Stemness via Notch Pathway Activation in Triple-Negative Breast Cancer Cells
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78. MicroRNA-141-regulated KLK10 and TNFSF-15 gene expression in hepatoblastoma cells as a novel mechanism in liver carcinogenesis
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79. Mechanisms and therapeutic strategies linking mesenchymal stem cells senescence to osteoporosis
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80. Spatial transcriptomics reveals immune-stromal crosstalk within the synovium of patients with juvenile idiopathic arthritis
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81. GBA inhibition suppresses ovarian cancer growth, survival and receptor tyrosine kinase AXL-mediated signaling pathways
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82. S100A8 alarmin supports IL-6 and metalloproteinase-9 production by fibroblasts in the synovial microenvironment of peripheral spondyloarthritis
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83. Diagnostic performance of type I hypersensitivity-specific markers combined with CRP and IL-6 in complicated acute appendicitis in pediatric patients
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84. Liposome Vaccine for Active Regulation of Cellular and Humoral Immunity
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85. Immunomodulatory performance of GMP-compliant, clinical-grade mesenchymal stromal cells from four different sources
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86. PLGA-Chitosan Encapsulated IL-10 Nanoparticles Modulate Chlamydia Inflammation in Mice
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87. Exploring Anti-Fibrotic Effects of Adipose-Derived Stem Cells: Transcriptome Analysis upon Fibrotic, Inflammatory, and Hypoxic Conditioning
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88. Magnetic nanoparticle-based combination therapy: Synthesis and in vitro proof of concept of CrFe2O4- rosmarinic acid nanoparticles for anti-inflammatory and antioxidant therapy
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89. A strategic review of STAT3 signaling inhibition by phytochemicals for cancer prevention and treatment: Advances and insights
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90. Mung Bean Functional Protein Enhances Endothelial Function via Antioxidant Activity and Inflammation Modulation in Middle-Aged Adults: A Randomized Double-Blind Trial
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91. Investigating T Cell Immune Dynamics and IL-6’s Duality in a Microfluidic Lung Tumor Model
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92. Interleukin-6 Modulation in Ovarian Cancer Necessitates a Targeted Strategy: From the Approved to Emerging Therapies
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93. Venous Thromboembolic Events in Cancer Immunotherapy: A Narrative Review
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94. miRNA-320 inhibits colitis-associated colorectal cancer by regulating the IL-6R/STAT3 pathway in mice
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95. IL-21/IL-21R Regulates the Neutrophil-Mediated Pathologic Immune Response during Chlamydial Respiratory Infection
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96. 3D Models as a Tool to Assess the Anti-Tumor Efficacy of Therapeutic Antibodies: Advantages and Limitations
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97. Placental transcriptional signatures associated with cerebral white matter damage in the neonate
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98. Corylin inhibits the progression of Non-small cell lung cancer cells by regulating NF-κB signaling pathway via targeting p65
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99. Anti‐inflammatory properties of an aldehydes‐enriched fraction of grapefruit essential oil
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100. Enzyme‐Activatable Polypeptide for Plasma Membrane Disruption and Antitumor Immunity Elicitation
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