Cited by 25Biomedical Text Mining and OntologiesMachine Learning in HealthcareTopic Modeling

Extracting social determinants of health events with transformer-based multitask, multilabel named entity recognition

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Richie, Russell, Ruiz, Victor M, Han, Sifei, Shi, Lingyun, Tsui, Fuchiang (Rich)·2023·Journal of the American Medical Informatics Association

Abstract

Objective: Social determinants of health (SDOH) are nonclinical, socioeconomic conditions that influence patient health and quality of life. Identifying SDOH may help clinicians target interventions. However, SDOH are more frequently available in narrative notes compared to structured electronic health records. The 2022 n2c2 Track 2 competition released clinical notes annotated for SDOH to promote development of NLP systems for extracting SDOH. We developed a system addressing 3 limitations in state-of-the-art SDOH extraction: the inability to identify multiple SDOH events of the same type per sentence, overlapping SDOH attributes within text spans, and SDOH spanning multiple sentences. Materials and Methods: We developed and evaluated a 2-stage architecture. In stage 1, we trained a BioClinical-BERT-based named entity recognition system to extract SDOH event triggers, that is, text spans indicating substance use, employment, or living status. In stage 2, we trained a multitask, multilabel NER to extract arguments (eg, alcohol “type”) for events extracted in stage 1. Evaluation was performed across 3 subtasks differing by provenance of training and validation data using precision, recall, and F1 scores. Results: When trained and validated on data from the same site, we achieved 0.87 precision, 0.89 recall, and 0.88 F1. Across all subtasks, we ranked between second and fourth place in the competition and always within 0.02 F1 from first. Conclusions: Our 2-stage, deep-learning-based NLP system effectively extracted SDOH events from clinical notes. This was achieved with a novel classification framework that leveraged simpler architectures compared to state-of-the-art systems. Improved SDOH extraction may help clinicians improve health outcomes.

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Authors
Richie, R., Ruiz, V. M., Han, S., Shi, L., & Tsui, F. (.
Affiliations
Children's Hospital of Philadelphia (US)
Corresponding author
Tsui, Fuchiang (Rich)
Venue
Journal of the American Medical Informatics Association
Published
2023-03-21
Volume
30
Issue
8
Pages
1379-1388
ISSN
  • 1067-5027 (ISSN-L)
  • 1527-974X
OpenAlex
W4362456756
Cited by
25
References
30
Citations by year
2026: 3 · 2025: 14 · 2024: 6 · 2023: 2
FWCI
2.22
Type
journal article
Language
en
Open access
Locations
  • Journal of the American Medical Informatics Association (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institute of Mental Health (R21MH130853-01)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Biomedical Text Mining and Ontologies
  • Physical Sciences › Computer Science › Artificial Intelligence › Machine Learning in Healthcare
  • Physical Sciences › Computer Science › Artificial Intelligence › Topic Modeling
Keywords
social determinants of health, named entity recognition, clinical notes, transformer models, substance use, employment, living status, clinical text mining
MeSH terms
Ethanol, Humans, Natural Language Processing, Quality of Life, Narration, Electronic Health Records, Social Determinants of Health

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