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Prospective Study of the Frequency and Size Distribution of Polyps Missed by Colonoscopy
Abstract
An important determinant in interpreting the results of colorectal polyp chemoprevention trials is the rate of polyps missed during colonscopic examination. We prospectively examined 90 patients by tandem colonoscopy performed by two alternating examiners. In 69 (76.7%) patients, 221 neoplastic lesions were documented histologically. Of a total of 58 lesions detected in 31 patients, no neoplastic lesion greater than or equal to 10 mm in size was missed; 16% of diminutive (less than or equal to 5 mm) neoplastic polyps and 12.3% of medium-sized (6-9 mm) neoplastic polyps were missed by the first examiner. We conclude that an experienced colonoscopist will miss about 15% of colorectal neoplastic polyps less than 10 mm in size in the setting of adequate bowel preparation. Large (greater than or equal to 10 mm) polyps were rarely missed, however, with the "miss" rate in our study equal to 0, with a 95% confidence limit of 4.64%.
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Cited by
Adenoma detection rate and risk of colorectal cancer and death
Corley, D. A., Jensen, C. D., Marks, A. R., Zhao, W. K., Lee, J. K., Doubeni, C. A., Zauber, A. G., de Boer, J., Fireman, B. H., Schottinger, J. E., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1309086 · Cited by 2,270
Quality indicators for colonoscopy
Rex, D. K., Schoenfeld, P. S., Cohen, J., Pike, I. M., Adler, D. G., Fennerty, M. B., Lieb, J. G., Park, W. G., Rizk, M. K., Sawhney, M. S., et al. (2015) · Gastrointestinal Endoscopy · doi:10.1016/j.gie.2014.07.058 · Cited by 1,764
Self-citationRex, D. K., Bond, J. H., Winawer, S. J., Levin, T. R., Burt, R. W., Johnson, D. A., Kirk, L. M., Litlin, S., Lieberman, D. A., Waye, J. D., et al. (2002) · The American Journal of Gastroenterology · doi:10.1016/s0002-9270(02)04168-0 · Cited by 1,049
A Comparison of Virtual and Conventional Colonoscopy for the Detection of Colorectal Polyps
Fenlon, H. M., Nunes, D. P., Schroy, P. C., Barish, M. A., Clarke, P. D., & Ferrucci, J. T. (1999) · New England Journal of Medicine · doi:10.1056/nejm199911113412003 · Cited by 746
Chen, S. C., & Rex, D. K. (2007) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.01054.x · Cited by 403
Metadata
- Authors
- Hixson, L. J., Fennerty, M. B., Sampliner, R. E., McGee, D., & Garewal, H.
- Venue
- JNCI: Journal of the National Cancer Institute
- Publisher
- Oxford University Press (OUP)
- Published
- 1990-11-21
- Volume
- 82
- Issue
- 22
- Pages
- 1769-1772
- ISSN
- 0027-8874 (ISSN-L)
- 1460-2105
- OpenAlex
- W2107647287
- Cited by
- 338
- References
- 0
- FWCI
- 0.79
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Prospective Study of the Frequency and Size Distribution of Polyps Missed by Colonoscopy. https://app.cochat.ai/papers/10.1093/jnci/82.22.1769
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- Hixson, L. J., Fennerty, M. B., Sampliner, R. E., McGee, D., & Garewal, H. (1990). Prospective Study of the Frequency and Size Distribution of Polyps Missed by Colonoscopy. JNCI: Journal of the National Cancer Institute. https://doi.org/10.1093/jnci/82.22.1769
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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