The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK)
Abstract
Despite years of research and hundreds of reports on tumor markers in oncology, the number of markers that have emerged as clinically useful is pitifully small. Often, initially reported studies of a marker show great promise, but subsequent studies on the same or related markers yield inconsistent conclusions or stand in direct contradiction to the promising results. It is imperative that we attempt to understand the reasons that multiple studies of the same marker lead to differing conclusions. A variety of methodologic problems have been cited to explain these discrepancies. Unfortunately, many tumor marker studies have not been reported in a rigorous fashion, and published articles often lack sufficient information to allow adequate assessment of the quality of the study or the generalizability of study results. The development of guidelines for the reporting of tumor marker studies was a major recommendation of the National Cancer Institute-European Organisation for Research and Treatment of Cancer (NCI-EORTC) First International Meeting on Cancer Diagnostics in 2000. As for the successful CONSORT initiative for randomized trials and for the STARD statement for diagnostic studies, we suggest guidelines to provide relevant information about the study design, preplanned hypotheses, patient and specimen characteristics, assay methods, and statistical analysis methods. In addition, the guidelines suggest helpful presentations of data and important elements to include in discussions. The goal of these guidelines is to encourage transparent and complete reporting so that the relevant information will be available to others to help them to judge the usefulness of the data and understand the context in which the conclusions apply.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“While making revisions, conscious efforts were made to harmonize our recommendations with other reporting guidelines, and where possible we chose the same or similar wording for items [37,39,41,45,46].”
From Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): the TRIPOD Statement (2015) · cites this paper as [37]
In the citing paper
“These items have been identified as important in several well-known guidelines for reporting of clinical research [4],[38]–[41].”
From Reporting and Methods in Clinical Prediction Research: A Systematic Review (2012) · cites this paper as [4]
In the citing paper
“Most guidelines, such as the STROBE guidelines for the reporting of observational studies or the REMARK guidelines for tumour marker prognostic studies, specifically advise investigators to report both unadjusted results (i.e., from univariable analysis, yielding the association of each candidate predictor with the outcome) and adjusted results (i.e., from a multivariable analysis) [4],[38],[63].”
From Reporting and Methods in Clinical Prediction Research: A Systematic Review (2012) · cites this paper as [4]
In the citing paper
“However, none of these guidelines are entirely appropriate for prediction model studies.”
From Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis (TRIPOD): The TRIPOD Statement (2015) · cites this paper as [37]
In the citing paper
“However, the focus of the REMARK checklist is primarily on prognostic factors and not prediction models, whereas the GRIPS statement is aimed at risk prediction using genetic risk factors and the specific methodological issues around handling large numbers of genetic variants.”
From Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis (TRIPOD): The TRIPOD Statement (2015) · cites this paper as [37]
Citations
Cites
Meta-analysis of Observational Studies in Epidemiology<SUBTITLE>A Proposal for Reporting</SUBTITLE>
Stroup, D. F. (2000) · JAMA · doi:10.1001/jama.283.15.2008 · Cited by 20,623
Moher, D., Schulz, K. F., & Altman, D. G. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04337-3 · Cited by 5,373
Self-citationMoher, D., Cook, D. J., Eastwood, S., Olkin, I., Rennie, D., & Stroup, D. F. (1999) · The Lancet · doi:10.1016/s0140-6736(99)04149-5 · Cited by 4,826
The Revised CONSORT Statement for Reporting Randomized Trials: Explanation and Elaboration
Altman, D. G., Schulz, K. F., Moher, D., Egger, M., Davidoff, F., Elbourne, D., Gøtzsche, P. C., Lang, T., & for the CONSORT Group (2001) · Annals of Internal Medicine · doi:10.7326/0003-4819-134-8-200104170-00012 · Cited by 3,835
Self-citationTowards complete and accurate reporting of studies of diagnostic accuracy: The STARD Initiative.
Bossuyt, P. M., Reitsma, J. B., Bruns, D. E., Gatsonis, C. A., Glasziou, P. P., Irwig, L. M., Lijmer, J. G., Moher, D., Rennie, D., de Vet, H. C. W., et al. (2003) · Annals of Internal Medicine · doi:10.7326/0003-4819-138-1-200301070-00010 · Cited by 3,219
Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative
Bossuyt, P. M., Reitsma, J. B., Bruns, D. E., Gatsonis, C. A., Glasziou, P. P., Irwig, L. M., Lijmer, J. G., Moher, D., Rennie, D., & de Vet, H. C. W. (2003) · BMJ · doi:10.1136/bmj.326.7379.41 · Cited by 3,215
Moher, D. (2001) · JAMA · doi:10.1001/jama.285.15.1987 · Cited by 2,545
Systematic Reviews in Health Care : Meta-Analysis in Context
Egger, M., Smith, G. D., & Altman, D. G. (2000) · Cited by 2,312
Self-citationDangers of Using "Optimal" Cutpoints in the Evaluation of Prognostic Factors
Altman, D. G., Lausen, B., Sauerbrei, W., & Schumacher, M. (1994) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/86.11.829 · Cited by 1,143
Self-citationThe Risk of Determining Risk with Multivariable Models
Concato, J., Feinstein, A. R., & Holford, T. R. (1993) · Annals of Internal Medicine · doi:10.7326/0003-4819-118-3-199302010-00009 · Cited by 1,129
Cited by
Sorted by citations
Items 101–200 of 1,003
Angiogenesis in Breast Cancer Progression, Diagnosis, and Treatment
Madu, C. O., Wang, S. Y., Madu, C. O., & Lu, Y. W. (2020) · Journal of Cancer · doi:10.7150/jca.44313 · Cited by 261
Circulating Tumor Cells as Biomarkers in Prostate Cancer
Danila, D. C., Fleisher, M., & Scher, H. I. (2011) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-10-2650 · Cited by 244
Ki67 Expression and Docetaxel Efficacy in Patients With Estrogen Receptor–Positive Breast Cancer
Penault-Llorca, F. M., André, F., Sagan, C., Lacroix‐Triki, M., Denoux, Y., Verrièle, V., Jacquemier, J. D., Baranzelli, M. C., Bibeau, F., Antoine, M., et al. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2008.18.2808 · Cited by 243
Shao, Y., Sun, X., He, Y., Liu, C., & Liu, H. (2015) · PLoS ONE · doi:10.1371/journal.pone.0133830 · Cited by 239
Grinchuk, O. V., Yenamandra, S. P., Iyer, R., Singh, M., Lee, H. K., Lim, K. H., Chow, P. K. H., & Kuznetsov, V. A. (2017) · Molecular Oncology · doi:10.1002/1878-0261.12153 · Cited by 240
Engstrøm, M. J., Opdahl, S., Hagen, A. I., Romundstad, P., Akslen, L. A., Haugen, O. A., VATTEN, L. J., & Bofin, A. M. (2013) · Breast Cancer Research and Treatment · doi:10.1007/s10549-013-2647-2 · Cited by 238
Budhu, A., Roessler, S. K., Zhao, X., Yu, Z., Forgues, M., Ji, J., Karoly, E. D., Qin, L., Ye, Q., Jia, H., et al. (2013) · Gastroenterology · doi:10.1053/j.gastro.2013.01.054 · Cited by 238
Hou, J., Greystoke, A., Lancashire, L., Cummings, J., Ward, T. H., Ruth Board, Amir, E., Hughes, S., Krebs, M., Hughes, A. M., et al. (2009) · American Journal Of Pathology · doi:10.2353/ajpath.2009.090078 · Cited by 238
Marsh, S., Paul, J., King, C. R., Gifford, G., McLeod, H. L., & Brown, R. E. (2007) · Journal of Clinical Oncology · doi:10.1200/jco.2006.10.4752 · Cited by 238
Ignatiadis, M., Xenidis, N., Perraki, M., Apostolaki, S., Politaki, E., Kafousi, M., Stathopoulos, E. N., Stathopoulou, A., Lianidou, E. S., Chlouverakis, G., et al. (2007) · Journal of Clinical Oncology · doi:10.1200/jco.2007.11.7762 · Cited by 238
Sutcliffe, P., Hummel, S., Simpson, E., Young, T., Rees, A., Wilkinson, A., Hamdy, F. C., Clarke, N. W., & Staffurth, J. (2009) · Health Technology Assessment · doi:10.3310/hta13050 · Cited by 237
Hirko, K. A., Soliman, A. S., Banerjee, M., Ruterbusch, J. J., Harford, J. B., Chamberlain, R. M., Graff, J. J., Merajver, S. D., & Schwartz, K. (2013) · SpringerPlus · doi:10.1186/2193-1801-2-3 · Cited by 237
Gene signature evaluation as a prognostic tool: challenges in the design of the MINDACT trial
Bogaerts, J., Cardoso, F., Buyse, M. E., Braga, S. A., Loi, S., Harrison, J., Bines, J., Mook, S., Decker, N., Ravdin, P. M., et al. (2006) · Nature Clinical Practice Oncology · doi:10.1038/ncponc0591 · Cited by 235
Comprehensive Genomic Landscapes in Early and Later Onset Colorectal Cancer
Lieu, C. H., Golemis, E. A., Serebriiskii, I. G., Newberg, J. Y., Hemmerich, A. C., Connelly, C. F., Messersmith, W. A., Eng, C., Eckhardt, S. G., Frampton, G. M., et al. (2019) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-19-0899 · Cited by 234
Single circulating tumor cell detection and overall survival in nonmetastatic breast cancer
Bidard, F., Mathiot, C., Delaloge, S., Brain, E. G. C., Giachetti, S., de Crémoux, P., Marty, M. E., & Pierga, J. (2009) · Annals of Oncology · doi:10.1093/annonc/mdp391 · Cited by 232
Almost all articles on cancer prognostic markers report statistically significant results
Kyzas, P., Denaxa-Kyza, D., & Ioannidis, J. P. A. (2007) · European Journal of Cancer · doi:10.1016/j.ejca.2007.08.030 · Cited by 233
Baselga, J. M., Phillips, G. D. L., Verma, S., Ro, J., Huober, J., Guardino, A. E., Samant, M. K., Olsen, S., de Haas, S. L., & Pegram, M. D. (2016) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-15-2499 · Cited by 227
Loibl, S., Majewski, I. J., Guarneri, V., Nekljudova, V., Holmes, E. M., Bria, E., Denkert, C., Schem, C., Sotiriou, C. P., Loi, S., et al. (2016) · Annals of Oncology · doi:10.1093/annonc/mdw197 · Cited by 230
Taneja, S. S. (2015) · The Journal of Urology · doi:10.1016/j.juro.2015.02.070 · Cited by 228
Moon, P., Lee, J., Cho, Y., Lee, S. J., Jung, J. H., Chae, Y. S., Bae, H., Kim, Y., Kim, I., Park, H. Y., et al. (2015) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-15-0654 · Cited by 229
Prognostic Tools in Patients With Advanced Cancer: A Systematic Review
Simmons, C. P. L., McMillan, D. C., McWilliams, K., Sande, T. A., Fearon, K. C. H., Tuck, S., Fallon, M., & Laird, B. J. A. (2017) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2016.12.330 · Cited by 219
Jung, S., Kim, H. Y., Nam, B., Min, S. Y., Lee, S., Park, C., Kwon, Y., Kim, E., Ko, K. L., Shin, K. H., et al. (2010) · Breast Cancer Research and Treatment · doi:10.1007/s10549-010-0780-8 · Cited by 217
Lu, H., Arshad, M., Thornton, A., Avesani, G., Cunnea, P., Curry, E. W., Kanavati, F., Liang, J., Nixon, K., Williams, S. T., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-08718-9 · Cited by 213
Assessing the incremental value of diagnostic and prognostic markers: a review and illustration
Steyerberg, E. W., Pencina, M. J., Lingsma, H. F., Kattan, M. W., Vickers, A. J., & Van Calster, B. (2012) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2011.02562.x · Cited by 219
Personalized medicine using DNA biomarkers: a review
Ziegler, A., Koch, A., Krockenberger, K., & Großhennig, A. (2012) · Human Genetics · doi:10.1007/s00439-012-1188-9 · Cited by 213
Ericsson, P. I. G., Stovgaard, E. S., Sua, L. F., Reisenbichler, E., Kos, Z., Carter, J. M., Michiels, S., Quesne, J. P. C. L., Nielsen, T. O., Lænkholm, A., et al. (2020) · The Journal of Pathology · doi:10.1002/path.5406 · Cited by 215
Tumour budding: a promising parameter in colorectal cancer
Lugli, A., Karamitopoulou, E., & Zlobec, I. (2012) · British Journal of Cancer · doi:10.1038/bjc.2012.127 · Cited by 210
Schoenleber, S. J., Kurtz, D. M., Talwalkar, J. A., Roberts, L. R., & Gores, G. J. (2009) · British Journal of Cancer · doi:10.1038/sj.bjc.6605017 · Cited by 207
Validation of Biomarker-based risk prediction models
Taylor, J. M. G., Ankerst, D., & Andridge, R. (2008) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-07-4534 · Cited by 207
Dhingra, R., & Vasan, R. S. (2016) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2016.07.005 · Cited by 221
Collins, G. S., Omar, O., Shanyinde, M., & Yu, L.-M. (2013) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2012.06.020 · Cited by 192
Finkelmeier, F., Canli, Ö., Tal, A. O., Pleli, T., Trojan, J., Schmidt, M., Kronenberger, B., Zeuzem, S., Piiper, A., Greten, F. R., et al. (2016) · European Journal of Cancer · doi:10.1016/j.ejca.2016.03.002 · Cited by 204
Bidard, F., Madic, J., Mariani, P., Piperno-Neumann, S., Rampanou, A., Servois, V., Cassoux, N., Desjardins, L., Milder, M., Vaucher, I., et al. (2013) · International Journal of Cancer · doi:10.1002/ijc.28436 · Cited by 202
der Auwera, I. V., Cao, Y., Tille, J., Pepper, M. S., Jackson, D. G., Fox, S. B., Harris, A. L., Dirix, L. Y., & Vermeulen, P. (2006) · British Journal of Cancer · doi:10.1038/sj.bjc.6603445 · Cited by 202
Sparano, J. A., O’Neill, A., Alpaugh, K. R., Wolff, A. C., Northfelt, D., Dang, C. T., Sledge, G. W., & Miller, K. D. (2018) · JAMA Oncology · doi:10.1001/jamaoncol.2018.2574 · Cited by 205
Standard Preanalytical Coding for Biospecimens: Defining the Sample PREanalytical Code
Betsou, F., Lehmann, S., Ashton, G., Barnes, M., Benson, E. E., Coppola, D., DeSouza, Y., Eliason, J. F., Glazer, B., Guadagni, F., et al. (2010) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-09-1268 · Cited by 201
Sources of Bias in Specimens for Research About Molecular Markers for Cancer
Ransohoff, D. F., & Gourlay, M. L. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2009.25.6065 · Cited by 200
Heppner, B. I., Untch, M., Denkert, C., Pfitzner, B. M., Lederer, B., Schmitt, W., Eidtmann, H., Fasching, P. A., Tesch, H., Solbach, C., et al. (2016) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-15-2338 · Cited by 202
Vollebergh, M. A., Lips, E. H., Nederlof, P. M., Wessels, L. F. A., Schmidt, M. K., van Beers, E. H., Cornelissen, S., Holtkamp, M., Froklage, F. E., de Vries, E. G. E., et al. (2010) · Annals of Oncology · doi:10.1093/annonc/mdq624 · Cited by 198
Biospecimen reporting for improved study quality (BRISQ)
Moore, H. M., Kelly, A. B., Jewell, S. D., McShane, L. M., Clark, D. P., Greenspan, R., Hayes, D. F., Hainaut, P. L., Kim, P., Mansfield, E. A., et al. (2011) · Cancer Cytopathology · doi:10.1002/cncy.20147 · Cited by 199
Self-citationLapuk, A. V., Wu, C., Wyatt, A. W., McPherson, A., McConeghy, B. J., Brahmbhatt, S., Mo, F., Zoubeidi, A., Anderson, S. A., Bell, R. H., et al. (2012) · The Journal of Pathology · doi:10.1002/path.4047 · Cited by 196
Circulating tumour cells and outcome in non-metastatic colorectal cancer: a prospective study
Bork, U., Rahbari, N. N., Schölch, S., Reißfelder, C., Kahlert, C., Büchler, M. W., Weitz, J., & Koch, M. (2015) · British Journal of Cancer · doi:10.1038/bjc.2015.88 · Cited by 196
McGilvray, R. W., Eagle, R. A., Watson, N. F. S., Al-Attar, A., Ball, G., Jafferji, I., Trowsdale, J., & Durrant, L. G. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-09-0991 · Cited by 196
The role of imaging in the management of progressive glioblastoma
Ryken, T. C., Aygün, N., Morris, J., Schweizer, M. L., Nair, R., Spracklen, C. N., Kalkanis, S. N., & Olson, J. J. (2014) · Journal of Neuro-Oncology · doi:10.1007/s11060-013-1330-0 · Cited by 198
Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer
Carnielli, C. M., Macedo, C. C. S., Rossi, T. D., Granato, D. C., Rivera, C., Domingues, R. R., Pauletti, B. A., Yokoo, S., Heberle, H., Busso-Lopes, A. F., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-05696-2 · Cited by 196
A Plasma MicroRNA Panel for Detection of Colorectal Adenomas
Kanaan, Z. M., Roberts, H., Eichenberger, M. R., Billeter, A. T., Ocheretner, G., Pan, J., Rai, S. N., Jorden, J., Williford, A., & Galandiuk, S. (2013) · Annals of Surgery · doi:10.1097/sla.0b013e3182a15bcc · Cited by 194
Müller, V., Riethdorf, S., Rack, B. K., Janni, W., Fasching, P. A., Solomayer, E. F., Aktas, B., Kasimir‐Bauer, S., Pantel, K., & Fehm, T. N. (2012) · Breast Cancer Research · doi:10.1186/bcr3243 · Cited by 193
Lorente, D., Mateo, J., Templeton, A. J., Zafeiriou, Z., Bianchini, D., Ferraldeschi, R., Bahl, A. K., Shen, L., Su, Z. Z., Sartor, O. A., et al. (2014) · Annals of Oncology · doi:10.1093/annonc/mdu587 · Cited by 196
Meta-analysis confirms BCL2 is an independent prognostic marker in breast cancer
Callagy, G. M., Webber, M., Pharoah, P. D. P., & Caldas, C. (2008) · BMC Cancer · doi:10.1186/1471-2407-8-153 · Cited by 193
Bardet, S., Malville, E., Rame, J.-P., Babin, E., Samama, G., Raucourt, D. D., Michels, J.-J., Reznik, Y., & Henry-Amar, M. (2008) · European Journal of Endocrinology · doi:10.1530/eje-07-0603 · Cited by 193
Vandenbroucke, J. P., von Elm, E. B., Altman, D. G., Gøtzsche, P. C., Mulrow, C. D., Pocock, S., Poole, C., Schlesselman, J. J., & Egger, M. (2009) · Gaceta Sanitaria · doi:10.1016/j.gaceta.2008.12.001 · Cited by 215
Self-citationDanila, D. C., Anand, A., Sung, C. C., Heller, G., Leversha, M. A., Cao, L., Lilja, H. G., Molina, A., Sawyers, C. L., Fleisher, M., et al. (2011) · European Urology · doi:10.1016/j.eururo.2011.07.011 · Cited by 193
Merok, M. A., Ahlquist, T. C., Røyrvik, E. C., Tufteland, K. F., Hektoen, M., Sjo, O. H., Mala, T., Svindland, A., Lothe, R. A., & Nesbakken, A. (2012) · Annals of Oncology · doi:10.1093/annonc/mds614 · Cited by 190
Kodahl, A. R., Lyng, M., Binder, H., Cold, S., Thomsen, K. G., Knoop, A. S., & Ditzel, H. J. (2014) · Molecular Oncology · doi:10.1016/j.molonc.2014.03.002 · Cited by 189
Nitz, U. A., Gluz, O., Christgen, M., Kates, R. E., Clemens, M., Malter, W., Nuding, B., Aktas, B., Küemmel, S., Reimer, T., et al. (2017) · Breast Cancer Research and Treatment · doi:10.1007/s10549-017-4358-6 · Cited by 189
A conceptual framework for prognostic research
Kent, P. M., Cancelliere, C., Boyle, E., Cassidy, J. D., & Kongsted, A. (2020) · BMC Medical Research Methodology · doi:10.1186/s12874-020-01050-7 · Cited by 204
Crawford, F., Cezard, G. I., Chappell, F. M., Murray, G. D., Price, J. F., Sheikh, A., Simpson, C. R., Stansby, G. P., & Young, M. J. (2015) · Health Technology Assessment · doi:10.3310/hta19570 · Cited by 196
Publication of Tumor Marker Research Results: The Necessity for Complete and Transparent Reporting
McShane, L. M., & Hayes, D. F. (2012) · Journal of Clinical Oncology · doi:10.1200/jco.2012.42.6858 · Cited by 188
Self-citationTejpar, S., Bertagnolli, M. M., Bosman, F. T., Lenz, H.-J., Garraway, L. A., Waldman, F. M., Warren, R. S., Bild, A. H., Collins-Brennan, D., Hahn, H. P., et al. (2010) · The Oncologist · doi:10.1634/theoncologist.2009-0233 · Cited by 189
Yang, M. S., Kozminski, D. J., Wold, L. A., Modak, R., Calhoun, J. D., Isom, L. L., & Brackenbury, W. J. (2012) · Breast Cancer Research and Treatment · doi:10.1007/s10549-012-2102-9 · Cited by 184
Yagi, T., Baba, Y., Ishimoto, T., Iwatsuki, M., Miyamoto, Y., Yoshida, N., Watanabe, M., & Baba, H. (2017) · Annals of Surgery · doi:10.1097/sla.0000000000002616 · Cited by 181
Tissue Biomarkers for Prognosis in Cutaneous Melanoma: A Systematic Review and Meta-analysis
Rothberg, B. E. G., Bracken, M. B., & Rimm, D. L. (2009) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djp038 · Cited by 183
Yan, M., Jene, N., Byrne, D. J., Millar, E. K. A., O'Toole, S. A., McNeil, C. M., Bates, G. J., Harris, A. L., Banham, A. H., Sutherland, R. L., et al. (2011) · Breast Cancer Research · doi:10.1186/bcr2869 · Cited by 188
Biological Markers in DCIS and Risk of Breast Recurrence: A Systematic Review
Lari, S. A., & Kuerer, H. M. (2011) · Journal of Cancer · doi:10.7150/jca.2.232 · Cited by 179
Strategies for developing Ki67 as a useful biomarker in breast cancer
Denkert, C., Budczies, J., von Minckwitz, G., Wienert, S., Loibl, S., & Klauschen, F. (2015) · The Breast · doi:10.1016/j.breast.2015.07.017 · Cited by 177
CCAT2, a novel long non-coding RNA in breast cancer: expression study and clinical correlations
Redis, R. S., Sieuwerts, A. M., Look, M. P., Tudoran, O. M., Ivan, C., Spizzo, R., Zhang, X., de Weerd, V., Shimizu, M., Ling, H. Y., et al. (2013) · Oncotarget · doi:10.18632/oncotarget.1292 · Cited by 177
Tobacco Smoking-Associated Alterations in the Immune Microenvironment of Squamous Cell Carcinomas
Desrichard, A., Kuo, F., Chowell, D., Lee, K.-W., Riaz, N., Wong, R. J., Chan, T. A.-T., & Morris, L. G. T. (2018) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djy060 · Cited by 178
Prat, A., Pascual, T., Angelis, C. D., Gutiérrez, C., Llombart‐Cussac, A., Wang, T., Cortés, J., Rexer, B. N., Paré, L., Forero, A., et al. (2019) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djz042 · Cited by 171
Modelska, A., Turro, E., Russell, R. B., Beaton, J., Sbarrato, T., Spriggs, K. A., Miller, J. L., Gräf, S., Provenzano, E., Blows, F. M., et al. (2015) · Cell Death and Disease · doi:10.1038/cddis.2014.542 · Cited by 171
MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma
Zhang, W., Ni, M., Su, Y., Wang, H., Zhu, S., Zhao, A., & Li, G. (2016) · European Urology Focus · doi:10.1016/j.euf.2016.09.007 · Cited by 174
Dahabreh, I. J., Terasawa, T., Castaldi, P. J., & Trikalinos, T. A. (2011) · Annals of Internal Medicine · doi:10.7326/0003-4819-154-1-201101040-00006 · Cited by 174
The Use of Genomics in Clinical Trial Design
Simon, R. M. (2008) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-07-4531 · Cited by 171
Ozawa, T., Matsuyama, T., Toiyama, Y., Takahashi, N., Ishikawa, T., Uetake, H., Yamada, Y., Kusunoki, M., Călin, G. A., & Goel, A. (2017) · Annals of Oncology · doi:10.1093/annonc/mdx248 · Cited by 175
Sturgeon, C. M., Hoffman, B., Chan, D. W., Ch'ng, S.-L., Hammond, E., Hayes, D. F., Liotta, L. A., Petricoin, E. F., III, Schmitt, M., Semmes, O. J., et al. (2008) · Clinical Chemistry · doi:10.1373/clinchem.2007.094144 · Cited by 168
Rakaee, M., Busund, L., Jamaly, S., Paulsen, E., Richardsen, E., Andersen, S., Al-Saad, S., Bremnes, R., Donnem, T., & Kilvaer, T. (2019) · Neoplasia · doi:10.1016/j.neo.2019.01.005 · Cited by 133
Transcriptome Profiling Identifies HMGA2 as a Biomarker of Melanoma Progression and Prognosis
Raskin, L., Fullen, D. R., Giordano, T. J., Thomas, D. G., Frohm, M. L., Cha, K. B., Ahn, J., Mukherjee, B., Johnson, T. M., & Gruber, S. B. (2013) · Journal of Investigative Dermatology · doi:10.1038/jid.2013.197 · Cited by 168
Modlin, I. M., Drozdov, I. A., & Kidd, M. S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0063364 · Cited by 165
Singal, A. G., Hoshida, Y., Pinato, D. J., Marrero, J. A., Nault, J., Paradis, V., Tayob, N., Sherman, M., Lim, Y., Feng, Z., et al. (2021) · Gastroenterology · doi:10.1053/j.gastro.2021.01.233 · Cited by 170
Ransohoff, D. F. (2007) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2007.04.020 · Cited by 161
Ferrara, R., Naigeon, M., Auclin, É., Duchemann, B., Cassard, L., Jouniaux, J.-M., Boselli, L., Grivel, J., Desnoyer, A., Mezquita, L., et al. (2020) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-20-1420 · Cited by 169
Hemingway, H., Philipson, P., Chen, R., Fitzpatrick, N. K., Damant, J., Shipley, M. J., Abrams, K. R., Moreno, S. G., McAllister, K. S. L., Palmer, S., et al. (2010) · PLoS Medicine · doi:10.1371/journal.pmed.1000286 · Cited by 161
Markers of systemic inflammation predict survival in patients with advanced renal cell cancer
Fox, P., Hudson, H. M., Brown, C. S. B., Lord, S. J., Gebski, V., SOUZA, P. D., & Lee, C. K. (2013) · British Journal of Cancer · doi:10.1038/bjc.2013.300 · Cited by 164
Ten steps towards improving prognosis research
Hemingway, H., Riley, R. D., & Altman, D. G. (2009) · BMJ · doi:10.1136/bmj.b4184 · Cited by 160
Self-citationChang, R., Yang, H., Fang, F., Xu, J., & Yang, L. (2014) · Hepatology · doi:10.1002/hep.27221 · Cited by 159
DNA methylation-based biomarkers in bladder cancer
Kandimalla, R., van Tilborg, A. A., & Zwarthoff, E. C. (2013) · Nature Reviews Urology · doi:10.1038/nrurol.2013.89 · Cited by 159
Goh, J. Y., Feng, M., Wang, W., Oguz, G., Yatim, S. M. J. M., Lee, P. L., Bao, Y., Lim, T. H., Wang, P., Tam, W. L., et al. (2017) · Nature Medicine · doi:10.1038/nm.4405 · Cited by 158
Tumour budding is a strong and independent prognostic factor in pancreatic cancer
Karamitopoulou, E., Zlobec, I., Born, D., Kondi-Pafiti, A., Lykoudis, P. M., Mellou, A., Gennatas, K., Gloor, B., & Lugli, A. (2012) · European Journal of Cancer · doi:10.1016/j.ejca.2012.10.022 · Cited by 155
Emerging Biomarkers for the Diagnosis and Prognosis of Prostate Cancer
Sardana, G., Dowell, B. L., & Diamandis, E. P. (2008) · Clinical Chemistry · doi:10.1373/clinchem.2008.110668 · Cited by 156
Lassere, M. N. (2007) · Statistical Methods in Medical Research · doi:10.1177/0962280207082719 · Cited by 154
Down-Regulation of ECRG4, a Candidate Tumor Suppressor Gene, in Human Breast Cancer
Sabatier, R., Finetti, P., Adélaı̈de, J., Guillé, A., Borg, J., Chaffanet, M., Lane, L., Birnbaum, D., & Bertucci, F. (2011) · PLoS ONE · doi:10.1371/journal.pone.0027656 · Cited by 154
Trovik, J., Wik, E., Werner, H. M. J., Krakstad, C., Helland, H., Vandenput, I., Njølstad, T. S., Stefansson, I. M., Marcickiewicz, J., Tingulstad, S., et al. (2013) · European Journal of Cancer · doi:10.1016/j.ejca.2013.06.016 · Cited by 154
Circulating miR-200c as a diagnostic and prognostic biomarker for gastric cancer
Valladares‐Ayerbes, M., Reboredo, M., Villaamil, V. M., Iglesias-Díaz, P., Lorenzo-Patiño, M. J., Haz‐Conde, M., Santamarina, I., Blanco, M., Fernandez-Tajes, J. J., Quindós, M., et al. (2012) · Journal of Translational Medicine · doi:10.1186/1479-5876-10-186 · Cited by 153
Templeton, A. J., Knox, J. J., Lin, X., Simantov, R., Xie, W., Lawrence, N. J., Broom, R. J., Fay, A. P., Rini, B. I., Donskov, F. N., et al. (2016) · European Urology · doi:10.1016/j.eururo.2016.02.033 · Cited by 155
Peat, G., Riley, R. D., Croft, P. R., Morley, K. I., Kyzas, P., Moons, K. G. M., Perel, P., Steyerberg, E. W., Schroter, S., Altman, D. G., et al. (2014) · PLoS Medicine · doi:10.1371/journal.pmed.1001671 · Cited by 152
Self-citationSystematic Review: Gene Expression Profiling Assays in Early-Stage Breast Cancer
Marchionni, L., Wilson, R. F., Wolff, A. C., Marinopoulos, S. S., Parmigiani, G., Bass, E. B., & Goodman, S. N. (2008) · Annals of Internal Medicine · doi:10.7326/0003-4819-148-5-200803040-00208 · Cited by 148
Harris, L. N., Broadwater, G., Lin, N., Miron, A., Schnitt, S. J., Cowan, D., Lara, J. F., Bleiweiss, I. J., Berry, D. A., Ellis, M. J., et al. (2006) · Breast Cancer Research · doi:10.1186/bcr1622 · Cited by 154
Rosendahl, A. H., Perks, C. M., Zeng, L., Markkula, A., Simonsson, M., Rose, C., Ingvar, C., Holly, J. M. P., & Jernström, H. (2015) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-14-1748 · Cited by 150
Abdel-Fatah, T. M. A., Russell, R., Albarakati, N., Maloney, D. J., Dorjsuren, D. G., Rueda, O. M., Moseley, P. M., Mohan, V., Sun, H., Abbotts, R., et al. (2014) · Molecular Oncology · doi:10.1016/j.molonc.2014.04.009 · Cited by 148
Validation of New Cancer Biomarkers: A Position Statement from the European Group on Tumor Markers
Duffy, M. J., Sturgeon, C. M., Sölétormos, G., Barak, V., Molina, R., Hayes, D. F., Diamandis, E. P., & Bossuyt, P. M. (2015) · Clinical Chemistry · doi:10.1373/clinchem.2015.239863 · Cited by 148
Voss, M. A., Ganesan, R., Ludeman, L., McCarthy, K., Gornall, R., Schäller, G., Wei, W., & Sundar, S. S. (2011) · Gynecologic Oncology · doi:10.1016/j.ygyno.2011.07.030 · Cited by 149
Metadata
- Authors
- McShane, L. M., Altman, D. G., Sauerbrei, W., Taube, S. E., Gion, M., & Clark, G. M.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- McShane, Lisa M.
- Venue
- JNCI: Journal of the National Cancer Institute
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-08-17
- Volume
- 97
- Issue
- 16
- Pages
- 1180-1184
- ISSN
- 0027-8874 (ISSN-L)
- 1460-2105
- OpenAlex
- W2096910745
- Cited by
- 2,162
- References
- 46
- Citations by year
- 2026: 112 · 2025: 38 · 2024: 44 · 2023: 42 · 2022: 39 · 2021: 93 · 2020: 100 · 2019: 126 · 2018: 116 · 2017: 127 · 2016: 163 · 2015: 192 · 2014: 167 · 2013: 150 · 2012: 173
- FWCI
- 56.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- JNCI Journal of the National Cancer Institute (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Yale University
- Yale Cancer Center
- Cancer Research UK
- Translational Cancer Research Network
- National Cancer Institute (MD 20892, 20892)
- Topics
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Epidemiology
- Health Sciences › Medicine › Oncology › Cancer Diagnosis and Treatment
- Keywords
- tumor markers, prognostic factors, reporting guidelines, remarks, reporting quality, methodological discrepancies, research design, assay method, statistical analysis methods, cancer diagnosis, research transparency
- MeSH terms
- Humans, Neoplasms, Research Design, Biomarkers, Tumor, Information Dissemination, Biomedical Research
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
