Pathology and Genetics of Tumours of the Nervous System

Abstract

The new edition of this publication opens with the recently revised WHO Classification of Tumors of the Nervous System (Working Group, 1999) and then systematically presents each of these tumors and familial tumor syndromes in a standardized format with the following subheadings: definition, incidence, age and sex distribution, localization, clinical features, neuroimaging, pathology, immunohistochemistry, tumor progression, growth pattern, proliferation, genetic susceptibility, cytogenetics, molecular genetics, histogenesis, and predictive factors. As the title foretells, the main emphasis is on pathology and genetics, including a thorough update of the multiple genetic pathways of tumor development and progression. The 2600 cited references have been expanded by 862 since the 1997 edition, providing remarkable currency for a multi-authored book of this type and demonstrating the rapid progress in this field. The 109 authors have summarized this voluminous literature in a direct, terse, readable style. There are over 500 illustrations, charts, and tables that are highly informative and discriminating. All pathology is presented in color. This book provides an accessible, worthy resource and a valuable guidepost for new or experienced travelers in this realm.