The DOI matches its Crossref record.
The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders: An Introduction
Abstract
This chapter recounts the origins of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) as it developed over a period of several decades. The rationale for developing it was derived from research emerging over this period of time that highlighted commonalities among anxiety, depressive, and related disorders, focusing on emotional disruption and dysregulation, as well as research highlighting common underlying temperamental factors associated with all these disorders. With a particular emphasis on the temperament of neuroticism, transdiagnostic constructs in emotional disorders that are fundamental aspects of neuroticism, such as increased anxiety sensitivity, decreased mindfulness, experiential avoidance, and negative appraisals and attributions, were identified and became targets for treatment. After presentation of the core elements comprising the UP, research supporting its efficacy, including a recently completed large clinical trial, is presented.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“or they are uncontrolled trials [50-52].”
From Negative and positive affect regulation in a transdiagnostic internet-based protocol for emotional disorders: Randomized controlled trial (2021) · cites this paper as [51]
Citations
Cited by
Sorted by citations
Winhusen, T. M., Walley, A. Y., Fanucchi, L. C., Hunt, T., Lyons, M., Lofwall, M. R., Brown, J. L., Freeman, P. R., Nunes, E. V., Beers, D., et al. (2020) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2020.108325 · Cited by 135
Wright, A. G. C., Pincus, A. L., & Hopwood, C. J. (2023) · Journal of Psychopathology and Clinical Science · doi:10.1037/abn0000741 · Cited by 105
Lungu, A., Jun, J. J., Azarmanesh, O., Leykin, Y., & Chen, C. E.-J. (2020) · Journal of Medical Internet Research · doi:10.2196/18723 · Cited by 75
Southward, M. W., Sauer-Zavala, S. E., & Cheavens, J. S. (2021) · Clinical Psychology Science and Practice · doi:10.1037/cps0000003 · Cited by 69
Díaz-García, A., González-Robles, A., García-Palacios, A., Fernández-Álvarez, J., Castilla, D., Bretón, J. M., Baños, R. M., Quero, S., & Botella, C. (2021) · Journal of Medical Internet Research · doi:10.2196/21335 · Cited by 36
Wright, A. G. C., Pincus, A. L., & Hopwood, C. J. (2020) · doi:10.31234/osf.io/fknc8 · Cited by 34
Sauer-Zavala, S. E., Southward, M. W., Stumpp, N. E., Semcho, S., Hood, C. O., Garlock, A., & Urs, A. (2022) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2022.2053571 · Cited by 35
Bentley, K. H., Sauer-Zavala, S., Stevens, K. T., & Washburn, J. J. (2020) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2018.09.012 · Cited by 28
Piers, R. J., Farchione, T. J., Wong, B., Rosellini, A. J., & Cronin‐Golomb, A. (2022) · Movement Disorders Clinical Practice · doi:10.1002/mdc3.13587 · Cited by 25
The emotional underpinnings of personality pathology: Implications for psychotherapy.
Kramer, U., & Timulák, L. (2022) · Clinical Psychology Science and Practice · doi:10.1037/cps0000080 · Cited by 22
Experimental Manipulations to Test Theory-Driven Mechanisms of Cognitive Behavior Therapy
Southward, M. W., & Sauer-Zavala, S. E. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.603009 · Cited by 17
Timulák, L., Keogh, D., McElvaney, J., Schmitt, S., Hession, N., Timulakova, K., Jennings, C. J., & Ward, F. (2020) · HRB Open Research · doi:10.12688/hrbopenres.12993.1 · Cited by 17
Trombetta, T., & Rollè, L. (2023) · Journal of Interpersonal Violence · doi:10.1177/08862605231201822 · Cited by 12
A network approach to emotion regulation and symptom activation in depression and anxiety
Rodrigues, A. R., Castro, D., Cardoso, J., Ferreira, F., Serrão, C., Coelho, C. M., Meira, L., & Ferreira, T. B. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1362148 · Cited by 12
Nwankwo, G. N. A., Kook, M., Goetz, A. R., Campos, J. M. A., Cepeda, S. L., Hana, L. M., Weinzimmer, S. A., Schneider, S. C., Kennedy, S. M., Ehrenreich, J. T., et al. (2021) · Psychiatry Research Communications · doi:10.1016/j.psycom.2021.100008 · Cited by 10
Beeman, C., Davis, E. B., Voytenko, V. L., McConnell, J. R., Lemke, A. W., Douce, T., Walk, T., Mills, N. D., Phillips, K. P., Marseilles, R., et al. (2024) · Journal of Affective Disorders Reports · doi:10.1016/j.jadr.2023.100709 · Cited by 11
Kleiman, E. M., Bentley, K. H., Jaroszewski, A. C., Maimone, J. S., Fortgang, R. G., Zuromski, K. L., Kilbury, E. N., Stein, M. B., Beck, S., Huffman, J. C., et al. (2024) · Archives of Suicide Research · doi:10.1080/13811118.2024.2391293 · Cited by 7
Limowski, A. R., DeJesus, C. R., Ward‐Ciesielski, E. F., & McDermott, M. J. (2021) · Journal of American College Health · doi:10.1080/07448481.2021.1909039 · Cited by 8
Mechanism engagement as a potential evidence-based approach to personalized treatment termination
Sauer-Zavala, S. E., Southward, M. W., Terrill, D. R., Semcho, S., & Stumpp, N. E. (2023) · Psychotherapy Research · doi:10.1080/10503307.2023.2168574 · Cited by 6
Celleri, M., Cremades, C. F., Rojas, R. L., Garay, C. J., & Osma, J. (2023) · Acción Psicológica · doi:10.5944/ap.19.2.37004 · Cited by 7
Multiple-Baseline Design Study of Deliberate Practice for Learning Psychotherapeutic Techniques
Young, J. N., Schruff, M. A., Humphrey, C., & Pavlacic, J. M. (2023) · Evidence-Based Practice in Child and Adolescent Mental Health · doi:10.1080/23794925.2023.2272949 · Cited by 5
The unified protocol: patient and therapist perspectives on the utility of the group manual
Christensen, A. B., Gryesten, J. R., Kokholm, J., Vislie, K., Reinholt, N., Dichmann, K., Poulsen, S., & Arnfred, S. (2022) · Clinical Psychologist · doi:10.1080/13284207.2022.2061340 · Cited by 7
Feasibility and clinical usefulness of the Unified Protocol in women survivors of violence
Osma, J., Quilez-Orden, A. B., Ferreres-Galán, V., Meseguer, M. C., & Ariza, S. (2022) · Journal of Child and Family Studies · doi:10.1007/s10826-022-02226-z · Cited by 7
Das Unified Protocol zur Behandlung emotionaler Störungen: One size fits all?
Boettcher, J., Schaeuffele, C., & Renneberg, B. (2018) · Psychotherapeut · doi:10.1007/s00278-018-0282-4 · Cited by 4
Translating the Transdiagnostic: Aligning Assessment Practices With Research Advances
Vize, C. E., & Wright, A. G. C. (2023) · Assessment · doi:10.1177/10731911231194996 · Cited by 7
Escala de Iniciativa de Crecimiento Personal-II: validación de la traducción al español en Paraguay
Vuyk, M. A., & Codas, G. (2022) · Ciencias Psicológicas · doi:10.22235/cp.v16i1.2657 · Cited by 4
Incorporating Deliberate Practice in the Process of Continual Therapeutic Skill Development
Young, J. N., & Maack, D. J. (2020) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2020.09.009 · Cited by 6
Benuto, L. T., Farchione, T. J., Cardona, N. D., Segovia, F. A. R., Casas, J. B., & Reyes, S. R. (2023) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2023.06.001 · Cited by 3
Existential Isolation: Theory, Empirical Findings, and Clinical Considerations
Helm, P. J., Chau, R. F., & Greenberg, J. (2022) · Springer eBooks · doi:10.1007/978-3-031-06932-1_6 · Cited by 4
Pedro, L. M. R., de Oliveira, M. C. S., Pereira, M., Fonseca, A., & Canavarro, M. C. (2024) · Administration and Policy in Mental Health and Mental Health Services Research · doi:10.1007/s10488-024-01391-1 · Cited by 4
Bortolon, C., & Nardelli, C. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106004 · Cited by 3
The Sufficiency of Scripture and Holistic Care: A Cursory Introduction
Lelek, J. (2021) · Journal of Psychology and Theology · doi:10.1177/00916471211011600 · Cited by 2
Ghaderi, F., Akrami, N., Namdari, K., & Abedi, A. (2023) · Practice in Clinical Psychology · doi:10.32598/jpcp.11.2.862.1 · Cited by 2
Celleri, M., Cremades, C. F., Rojas, L., & Garay, C. J. (2023) · Vertex Revista Argentina de Psiquiatría · doi:10.53680/vertex.v34i161.482 · Cited by 2
Changing the emotion process: The role of emotion regulation
Bjureberg, J., & Gross, J. J. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-95604-8.00015-0 · Cited by 6
Martin, A., & Gerlach, A. L. (2018) · Psychotherapeut · doi:10.1007/s00278-018-0288-y
TRANSDİYAGNOSTİK BİLİŞSEL DAVRANIŞÇI TERAPİ: BİR ÖRNEK OLARAK BÜTÜNLEŞİK PROTOKOLPreprint
Batmaz, S. (2020) · doi:10.31234/osf.io/fvy83
Exposure for Multiple Anxiety Disorders
Stewart, K. E., & Antony, M. M. (2022) · Springer eBooks · doi:10.1007/978-3-031-04927-9_2
Transdiagnostic Cognitive Behavioral Psychotherapy: Unified Protocol as an Example
Batmaz, S. (2023) · Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry · doi:10.18863/pgy.1064590 · Cited by 1
Vøllestad, J., Osnes, B., & Schanche, E. (2023) · Tidsskrift for Norsk psykologforening · doi:10.52734/pdtf4789
On the importance of studying change in emotion and mental health
Samson, A. C., Sander, D., & Kramer, U. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-95604-8.00017-4
Timulák, L., Dailey, J., Lunn, J., & McKnight, J. (2024) · Journal of Contemporary Psychotherapy · doi:10.1007/s10879-024-09645-7 · Cited by 1
Vatani, S., Nia, A. A. A., Ghasemzade, S., & Bonab, B. G. (2026) · The Neuroscience Journal of Shefaye Khatam · doi:10.66224/shefa.14.2.11
Group and online application of the Unified Protocol in Argentina: controlled pilot study
Kaplan, M., Celleri, M., Klajner, F., Cremades, C. F., & Garay, C. J. (2026) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2026.2720138
Metadata
- Authors
- Kennedy, K. A., & Barlow, D. H.
- ORCID
- Barlow, David H.
- Venue
- Applications of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Publisher
- Oxford University Press
- Published
- 2017-08
- Pages
- 1-16
- OpenAlex
- W4243572921
- Cited by
- 46
- References
- 0
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 7 · 2023: 13 · 2022: 8 · 2021: 5 · 2020: 7 · 2018: 3
- FWCI
- 11.29
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Oxford University Press eBooks (publishedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders, transdiagnostic treatment, emotional disorders, anxiety disorders, depression, emotional dysregulation, neuroticism, anxiety sensitivity, mindfulness, experiential avoidance, treatment efficacy
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review