Commentary: Autism Genetics and Genomics: A Brief Overview and Synthesis
Abstract
This commentary begins with a discussion of the development of autism genetics followed by a review of prominent genetic models. It then considers how common variation might influence the development of autism spectrum disorders; whether genetics point to specific molecular pathways and the implications for treatment; and autism vs. intellectual disability.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Common inherited variations and de novo genetic variation of low penetrance in multiple genes in critical biochemical and cellular pathways associated with neurodevelopment may underlie the autistic spectrum that extends on to the general population.
“In addition, common inherited variations (i.e., polymorphisms) and de novo genetic variation of low penetrance in multiple genes in critical biochemical and cellular pathways associated with neurodevelopment [62] may underlie the autistic spectrum that extends on to the general population.”
From Subgrouping the Autism Spectrum: Reflections on DSM-5 (2013) · cites this paper as [62]
Cited by
Sorted by citations
Subgrouping the Autism Spectrum: Reflections on DSM-5
Lai, M.-C., Lombardo, M. V., Chakrabarti, B., & Baron-Cohen, S. (2013) · PLoS Biology · doi:10.1371/journal.pbio.1001544 · Cited by 330 · see citing works
“, polymorphisms) and de novo genetic variation of low penetrance in multiple genes in critical biochemical and cellular pathways associated with neurodevelopment [62] may underlie the autistic spectrum that extends on to the general population.”
- Authors
- Geschwind, D. H.
- Corresponding author
- Geschwind, Daniel H.
- ORCID
- Geschwind, Daniel H.
- Venue
- Autism Spectrum Disorders
- Publisher
- Oxford University Press
- Published
- 2011-05
- Pages
- 812-824
- OpenAlex
- W2485313339
- Cited by
- 5
- References
- 0
- Citations by year
- 2020: 1 · 2018: 1 · 2015: 1 · 2013: 1 · 2012: 1
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Oxford University Press eBooks (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genomic variations and chromosomal abnormalities
- Keywords
- autism spectrum disorder, autism genetics, genetic models, common genetic variants, molecular pathways, autism treatment, intellectual disability
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
