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Post-transcriptional regulation of glyceraldehyde-3-phosphate-dehydrogenase gene expression in rat tissues
Open accessAbstract
We have isolated and identified cDNA clones containing part of the coding sequence for rat glyceraldehyde-3-phosphate-dehydrogenase (GAPDH, E.C. 1.2.1.12). By using one of these clones as a probe, we have shown that: i) the abundance of GAPDH mRNA is different in various tissues of the adult rat and in good correlation with the abundance of the enzyme; ii) the transcription rates are quite similar in all tissues tested. We therefore conclude that the tissue-specific differential GAPDH gene expression is regulated by adjusting the abundance of its mRNA at the post-transcriptional level.
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Cited by
Jiang, W., Swiggard, W. J., Heufler, C., Peng, M., Mirza, A., Steinman, R. M., & Nussenzweig, M. C. (1995) · Nature · doi:10.1038/375151a0 · Cited by 964
Defective inflammatory response in interleukin 6-deficient mice.
Fattori, E., Cappelletti, M., Costa, P., Sellitto, C., Cantoni, L., Carelli, M., Faggioni, R., Fantuzzi, G., Ghezzi, P., & Poli, V (1994) · The Journal of experimental medicine · doi:10.1084/jem.180.4.1243 · Cited by 525
Brain lipid-binding protein (BLBP): A novel signaling system in the developing mammalian CNS
Feng, L., Hatten, M. E., & Heintz, N. (1994) · Neuron · doi:10.1016/0896-6273(94)90341-7 · Cited by 494
Dardenne, O., Prud’homme, J., Arabian, A., Glorieux, F. H., & St-Arnaud, R. (2001) · Endocrinology · doi:10.1210/endo.142.7.8281 · Cited by 406
Inhibition of Myofibroblast Apoptosis by Transforming Growth Factor β 1
Zhang, H.-Y., & Phan, S. H. (1999) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/ajrcmb.21.6.3720 · Cited by 353
Metadata
- Authors
- Piechaczyk, M., Blanchard, J. M., Marty, L., Dani, C., Panabieres, F., El Sabouty, S., Fort, P., & Jeanteur, P.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 1984
- Volume
- 12
- Issue
- 18
- Pages
- 6951-6963
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W2034296167
- Cited by
- 480
- References
- 0
- FWCI
- 5.74
- Type
- journal article
- Language
- en
- Open access
- bronze
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- The paper
- Piechaczyk, M., Blanchard, J. M., Marty, L., Dani, C., Panabieres, F., El Sabouty, S., Fort, P., & Jeanteur, P. (1984). Post-transcriptional regulation of glyceraldehyde-3-phosphate-dehydrogenase gene expression in rat tissues. Nucleic Acids Research. https://doi.org/10.1093/nar/12.18.6951
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
