The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Human Lymphotoxin and tumor necrosis factor genes: structure, homology and chromosomal localization
Open accessAbstract
Human Tumor Necrosis Factor and Lymphotoxin are cytotoxic proteins which have similar biological activities and share 30 percent amino acid homology. The single copy genes which encode these proteins share several structural features: each gene is approximately three kilobase pairs in length and is interrupted by three introns. In addition, these genes are closely linked and have been mapped to human chromosome 6. However, only the last exons of both genes, which code for more than 80 percent of each secreted protein, are significantly homologous (56 percent).
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Citations
Cites
An endotoxin-induced serum factor that causes necrosis of tumors
Carswell, E. A., Old, L. J., Kassel, R. L., Green, S., Fiore, N., & Williamson, B. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.9.3666 · Cited by 4,532
Gilbert, W. (1978) · Nature · doi:10.1038/271501a0 · Cited by 2,300
Cited by
Cachectin and tumour necrosis factor as two sides of the same biological coin
Beutler, B., & Cerami, A. (1986) · Nature · doi:10.1038/320584a0 · Cited by 1,647
The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene
Klemsz, M. J., McKercher, S. R., Celada, A., Van Beveren, C., & Maki, R. A. (1990) · Cell · doi:10.1016/0092-8674(90)90219-5 · Cited by 954
Acute axonal injury in multiple sclerosis: Correlation with demyelination and inflammation
Bitsch, A. (2000) · Brain · doi:10.1093/brain/123.6.1174 · Cited by 898
Low nucleotide diversity in man.
Li, W. H., & Sadler, L. A. (1991) · Genetics · doi:10.1093/genetics/129.2.513 · Cited by 501
Poli, G., Kinter, A., Justement, J. S., Kehrl, J. H., Bressler, P., Stanley, S., & Fauci, A. S. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.2.782 · Cited by 457
Metadata
- Authors
- Nedwin, G. E., Naylor, S. L., Sakaguchi, A. Y., Smith, D., Jarrett-Nedwin, J., Pennica, D., Goeddel, D. V., & Gray, P. W.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 1985
- Volume
- 13
- Issue
- 17
- Pages
- 6361-6373
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W2096158027
- Cited by
- 504
- References
- 2
- FWCI
- 7.88
- Type
- journal article
- Language
- en
- Open access
- green
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- Nedwin, G. E., Naylor, S. L., Sakaguchi, A. Y., Smith, D., Jarrett-Nedwin, J., Pennica, D., Goeddel, D. V., & Gray, P. W. (1985). Human Lymphotoxin and tumor necrosis factor genes: structure, homology and chromosomal localization. Nucleic Acids Research. https://doi.org/10.1093/nar/13.17.6361
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