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Codon usage in Pseudomonas aeruginosa
Open accessAbstract
We have generated a codon usage table for Pseudomonas aeruginosa. Codon usage in P. aeruginosa is extremely biased. In contrast to E. coli and yeast, P. aeruginosa preferentially uses those codons within a synonymous codon group with the strongest predicted codon-anticodon interaction. We were unable to correlate a particular codon usage pattern with predicted levels of mRNA expressivity. The choice of a third base reflects the high guanine plus cytosine content of the P. aeruginosa genome (67.2%) and cytosine is the preferred nucleotide for the third codon position.
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Cited by
West, S. E. H., Schweizer, H. P., Dall, C., Sample, A. K., & Runyen-Janecky, L. J. (1994) · Gene · doi:10.1016/0378-1119(94)90237-2 · Cited by 567
Self-citationOrganization of the bacterial chromosome
KRAWIEC, S., & Riley, M. (1990) · Microbiological Reviews · doi:10.1128/mmbr.54.4.502-539.1990 · Cited by 386
Ochsner, U. A., Fiechter, A., & Reiser, J. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)32089-6 · Cited by 332
Hrabak, E. M., & Willis, D. K. (1992) · Journal of Bacteriology · doi:10.1128/jb.174.9.3011-3020.1992 · Cited by 218
Metadata
- Authors
- West, S. E. H., & Iglewski, B. H.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 1988
- Volume
- 16
- Issue
- 19
- Pages
- 9323-9335
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W2034357791
- Cited by
- 233
- References
- 0
- FWCI
- 6.35
- Type
- journal article
- Language
- en
- Open access
- green
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- West, S. E. H., & Iglewski, B. H. (1988). Codon usage in Pseudomonas aeruginosa. Nucleic Acids Research. https://doi.org/10.1093/nar/16.19.9323
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