The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Differential repair of UV damage in Saccharomyces cerevisiae
Open accessAbstract
Preferential repair of UV-induced damage is a phenomenon by which mammalian cells might enhance their survival. This paper presents the first evidence that preferential repair occurs in the lower eukaryote Saccharomyces cerevisiae. Moreover an unique approach is reported to compare identical sequences present on the same chromosome and only differing in expression. We determined the removal of pyrimidine dimers from two identical alpha-mating type loci and we were able to show that the active MAT alpha locus is repaired preferentially to the inactive HML alpha locus. In a sir-3 mutant, in which both loci are active this preference is not observed.
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Photoaddition by Furocoumarins
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Metadata
- Authors
- Terleth, C., van Sluis, C. A., & van de Putte, P.
- Affiliations
- Leiden University (NL)
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 1989
- Volume
- 17
- Issue
- 12
- Pages
- 4433-4439
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- PMC
- PMC318003
- OpenAlex
- W2090418393
- Cited by
- 115
- References
- 26
- Citations by year
- 2023: 1 · 2022: 1 · 2021: 1 · 2016: 1 · 2015: 1 · 2013: 1 · 2012: 2
- FWCI
- 4.51
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Nucleic Acids Research (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA Repair Mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nuclear Structure and Function
- Keywords
- UV-induced DNA damage, pyrimidine dimers, DNA repair, Saccharomyces cerevisiae, mating-type locus, gene expression
- MeSH terms
- DNA Damage, DNA Repair, DNA, Fungal, Dose-Response Relationship, Radiation, Genes, Fungal, Mutation, Pyrimidine Dimers, Saccharomyces cerevisiae, Transcription, Genetic, Ultraviolet Rays, Deoxyribonucleases, Type II Site-Specific
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