The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
A simple procedure for optimising the polymerase chain reaction (PCR) using modified Taguchi methods
Open accessAbstract
Taguchi methods are used widely as the basis for development trials during industrial process design. Here, we describe their suitability for optimisation of the PCR. Unlike conventional strategies, these arrays revealed the effects and interactions of specific reaction components simultaneously using just a few reactions, negating the need for extensive experimental investigation. Reaction components which effected product yield were easily determined. In addition, this technique was applied to the qualitative investigation of RAPD-PCR profiles, where optimisation of the size and distribution of a number of products was determined.
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Cites
Huang, M.-M., Arnheim, N., & Goodman, M. F. (1992) · Nucleic Acids Research · doi:10.1093/nar/20.17.4567 · Cited by 365
Cited by
Chen, Q., Barragan, A., Fernandez, V., Sundström, A., Schlichtherle, M., Sahlén, A., Carlson, J., Datta, S., & Wahlgren, M. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.187.1.15 · Cited by 294
Njiru, Z. K., Mikosza, A. S. J., Armstrong, T., Enyaru, J. C., Ndung'u, J. M., & Thompson, A. R. C. (2008) · PLoS Neglected Tropical Diseases · doi:10.1371/journal.pntd.0000147 · Cited by 268
Naglik, J. R., Rodgers, C. A., Shirlaw, P. J., Dobbie, J. L., Fernandes‐Naglik, L. L., Greenspan, D., Agabian, N., & Challacombe, S. J. (2003) · The Journal of Infectious Diseases · doi:10.1086/376536 · Cited by 206
In Vivo Analysis of Secreted Aspartyl Proteinase Expression in Human Oral Candidiasis
Naglik, J. R., Newport, G., White, T. C., Fernandes-Naglik, L. L., Greenspan, J. S., Greenspan, D., Sweet, S. P., Challacombe, S. J., & Agabian, N. (1999) · Infection and Immunity · doi:10.1128/iai.67.5.2482-2490.1999 · Cited by 193
Lian, C. H., & Liu, W. D. (2007) · Mycoses · doi:10.1111/j.1439-0507.2007.01384.x · Cited by 49
Metadata
- Authors
- Cobb, B. D., & CIarkson, J. M.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 1994
- Volume
- 22
- Issue
- 18
- Pages
- 3801-3805
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W1987695816
- Cited by
- 284
- References
- 1
- FWCI
- 1.35
- Type
- journal article
- Language
- en
- Open access
- green
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- Cobb, B. D., & CIarkson, J. M. (1994). A simple procedure for optimising the polymerase chain reaction (PCR) using modified Taguchi methods. Nucleic Acids Research. https://doi.org/10.1093/nar/22.18.3801
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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