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Cited by 244

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The PIR-International Protein Sequence Database

Barker, W. C., Garavelli, J. S., McGarvey, P. B., Marzec, C. R., Orcutt, B. C., Srinivasarao, G. Y., Yeh, L.-S. L., Ledley, R. S., Mewes, H.-W., Pfeiffer, F., Tsugita, A., Wu, C.·1999·Nucleic Acids Research

Abstract

The Protein Information Resource (PIR; http://wwwnbrf.georgetown.edu/pir/) supports research on molecular evolution, functional genomics, and computational biology by maintaining a comprehensive, non-redundant, well-organized and freely available protein sequence database. Since 1988 the database has been maintained collaboratively by PIR-International, an international association of data collection centers cooperating to develop this resource during a period of explosive growth in new sequence data and new computer technologies. The PIR Protein Sequence Database entries are classified into superfamilies, families and homology domains, for which sequence alignments are available. Full-scale family classification supports comparative genomics research, aids sequence annotation, assists database organization and improves database integrity. The PIR WWW server supports direct on-line sequence similarity searches, information retrieval, and knowledge discovery by providing the Protein Sequence Database and other supplementary databases. Sequence entries are extensively cross-referenced and hypertext-linked to major nucleic acid, literature, genome, structure, sequence alignment and family databases. The weekly release of the Protein Sequence Database can be accessed through the PIR Web site. The quarterly release of the database is freely available from our anonymous FTP server and is also available on CD-ROM with the accompanying ATLAS database search program.

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Metadata

Authors
Barker, W. C., Garavelli, J. S., McGarvey, P. B., Marzec, C. R., Orcutt, B. C., Srinivasarao, G. Y., Yeh, L.-S. L., Ledley, R. S., Mewes, H.-W., Pfeiffer, F., Tsugita, A., & Wu, C.
Venue
Nucleic Acids Research
Published
1999-01-01
Volume
27
Issue
1
Pages
39-43
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W4213208922
Cited by
244
References
0
FWCI
9.24
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The PIR-International Protein Sequence Database. https://app.cochat.ai/papers/10.1093/nar/27.1.39
The paper
Barker, W. C., Garavelli, J. S., McGarvey, P. B., Marzec, C. R., Orcutt, B. C., Srinivasarao, G. Y., Yeh, L.-S. L., Ledley, R. S., Mewes, H.-W., Pfeiffer, F., Tsugita, A., & Wu, C. (1999). The PIR-International Protein Sequence Database. Nucleic Acids Research. https://doi.org/10.1093/nar/27.1.39

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.