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IMGT, the international ImMunoGeneTics database

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Ruiz, M.·2000·Nucleic Acids Research

Abstract

IMGT, the international ImMunoGeneTics database (http://imgt.cines. fr:8104 ), is a high-quality integrated database specialising in Immunoglobulins (Ig), T cell Receptors (TcR) and Major Histocompatibility Complex (MHC) molecules of all vertebrate species, created in 1989 by Marie-Paule Lefranc, Université Montpellier II, CNRS, Montpellier, France (lefranc@ligm.igh.cnrs.fr ). At present, IMGT includes two databases: IMGT/LIGM-DB, a comprehensive database of Ig and TcR from human and other vertebrates, with translation for fully annotated sequences, and IMGT/HLA-DB, a database of the human MHC referred to as HLA (Human Leucocyte Antigens). The IMGT server provides a common access to expertized genomic, proteomic, structural and polymorphic data of Ig and TcR molecules of all vertebrates. By its high quality and its easy data distribution, IMGT has important implications in medical research (repertoire in autoimmune diseases, AIDS, leukemias, lymphomas), therapeutic approaches (antibody engineering), genome diversity and genome evolution studies. IMGT is freely available at http://imgt.cines.fr:8104. The IMGT Index is provided at the IMGT Marie-Paule page (http://imgt.cines.fr:8104/textes/IMGTindex.html).

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Metadata

Authors
Ruiz, M.
Venue
Nucleic Acids Research
Published
2000-01-01
Volume
28
Issue
1
Pages
219-221
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W2125604001
Cited by
858
References
1
FWCI
20.84
Type
journal article
Language
en
Open access
hybrid

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Ruiz, M. (2000). IMGT, the international ImMunoGeneTics database. Nucleic Acids Research. https://doi.org/10.1093/nar/28.1.219

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