Determination of L1 retrotransposition kinetics in cultured cells

Ostertag, E. M.·2000·Nucleic Acids Research
DOI 10.1093/nar/28.6.1418

Cited by (291)

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  2. sRNA/L1 retrotransposition: using siRNAs and miRNAs to expand the applications of the cell culture-based LINE-1 retrotransposition assay
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  3. The Impact of LINE-1 Retro transposition on the Human Genome
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  4. Robust expression of LINE-1 retrotransposon encoded proteins in oral squamous cell carcinoma
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  5. A genome-wide strategy to identify causes and consequences of retrotransposon expression finds activation by BRCA1 in ovarian cancer
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  9. BST2 Suppresses LINE-1 Retrotransposition by Reducing the Promoter Activity of LINE-1 5′ UTR
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  10. SINE Retrotransposition: Evaluation of Alu Activity and Recovery of De Novo Inserts
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  12. LINE‐1 Retrotransposition: Impact on Genome Stabilityand Diversity and Human Disease
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  13. LINE-1 ribonucleoprotein condensates bind DNA to enable nuclear entry during mitosis
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  14. Optimized R2 retroelement complexes for DNA insertion into plant genomes
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  16. Cell-host, LINE and environment
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  18. Efficient site-specific gene addition using R2 retrotransposons in tobacco and rice
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  21. Neuronal Genome Plasticity: Retrotransposons, Environment and Disease
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  23. Suppression of alternative telomere lengthening in cancer cells with reverse transcriptase inhibitors
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    Shreevidya Korada, Oliver H. Tam, Hunter C. Greco, Molly Hammell, Josh Dubnau, Roger B. Sher · 2025 · PLoS Genetics
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    Juliet Nicodemus, Christine S. Liu, Linnea Ransom, Valerie Tan, William J. Romanow, Natalia Jimenez, Jerold J. M. Chun · 2025 · Journal of Neuroscience
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  65. Non-LTR Retrotransposons in Mosquitoes: Diversity, Evolution, and Analysis of Potentially Active Elements
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