Cited by 354Forensic and Genetic ResearchGenetic diversity and population structureMolecular Biology Techniques and Applications

STRBase: A short tandem repeat DNA database for the human identity testing community

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Ruitberg, C. M.·2001·Nucleic Acids Research

Abstract

The National Institute of Standards and Technology (NIST) has compiled and maintained a Short Tandem Repeat DNA Internet Database (http://www.cstl.nist.gov/biotech/++ +strbase/) since 1997 commonly referred to as STRBase. This database is an information resource for the forensic DNA typing community with details on commonly used short tandem repeat (STR) DNA markers. STRBase consolidates and organizes the abundant literature on this subject to facilitate on-going efforts in DNA typing. Observed alleles and annotated sequence for each STR locus are described along with a review of STR analysis technologies. Additionally, commercially available STR multiplex kits are described, published polymerase chain reaction (PCR) primer sequences are reported, and validation studies conducted by a number of forensic laboratories are listed. To supplement the technical information, addresses for scientists and hyperlinks to organizations working in this area are available, along with the comprehensive reference list of over 1300 publications on STRs used for DNA typing purposes.

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  • The NIST Short Tandem Repeat DNA database provides in-depth information about STRs and other identification markers used in human identification testing.

    “Additionally, the recently updated Short Tandem Repeat DNA database hosted by the National Institute of Standards and Technology (NIST) provides in-depth information about STRs and other identification markers used in human identification testing [38,39].”

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Authors
Ruitberg, C. M.
Affiliations
National Institute of Standards and Technology (US)
Corresponding author
Ruitberg, C. M.
Venue
Nucleic Acids Research
Published
2001-01-01
Volume
29
Issue
1
Pages
320-322
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W2149588035
Cited by
354
References
0
Citations by year
2026: 9 · 2025: 16 · 2024: 17 · 2023: 15 · 2022: 13 · 2021: 14 · 2020: 14 · 2019: 15 · 2018: 23 · 2017: 14 · 2016: 25 · 2015: 21 · 2014: 21 · 2013: 10 · 2012: 10
FWCI
6.57
Type
journal article
Language
en
Open access
Locations
  • Nucleic Acids Research (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Forensic and Genetic Research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Molecular Biology Techniques and Applications
Keywords
microsatellite markers, forensic DNA profiling, STR markers, allele frequency, PCR primer sequences, validation studies, reference database
MeSH terms
Forensic Medicine, Genetic Markers, Humans, Genome, Human, Databases, Factual, Tandem Repeat Sequences, Internet

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