The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
DNA sequences from multiple amplifications reveal artifacts induced by cytosine deamination in ancient DNA
Open accessAbstract
We show that DNA molecules amplified by PCR from DNA extracted from animal bones and teeth that vary in age between 25 000 and over 50 000 years carry C-->T and G-->A substitutions. These substitutions can reach high proportions among the molecules amplified and are due to the occurrence of modified deoxycytidine residues in the template DNA. If the template DNA is treated with uracil N-glycosylase, these substitutions are dramatically reduced. They are thus likely to result from deamination of deoxycytidine residues. In addition, 'jumping PCR', i.e. the occurrence of template switching during PCR, may contribute to these substitutions. When DNA sequences are amplified from ancient DNA extracts where few template molecules initiate the PCR, precautions such as DNA sequence determination of multiple clones derived from more than one independent amplification are necessary in order to reduce the risk of determination of incorrect DNA sequences. When such precautionary measures are taken, errors induced by damage to the DNA template are unlikely to be more frequent than approximately 0.1% even under the unlikely scenario where each amplification starts from a single template molecule.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“This therefore results in a pattern of C-to-T substitutions. When a double-stranded library preparation is used, these substitutions can occur on the opposite strand thus resulting in G-to-A substitutions due to base complementarity.”
From <tt>SAFARI</tt> : pangenome alignment of ancient DNA using purine/pyrimidine encodings (2025) · cites this paper as [6]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Initial sequencing and analysis of the human genome
International Human Genome Sequencing Consortium, Whitehead Institute for Biomedical Research, C. F. G. R., Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., Devon, K., Dewar, K., et al. (2001) · Nature · doi:10.1038/35057062 · Cited by 24,216
Instability and decay of the primary structure of DNA
Lindahl, T. (1993) · Nature · doi:10.1038/362709a0 · Cited by 5,679
Neandertal DNA Sequences and the Origin of Modern Humans
Krings, M., Stone, A. C., Schmitz, R. W., Krainitzki, H., Stoneking, M., & Pääbo, S. (1997) · Cell · doi:10.1016/s0092-8674(00)80310-4 · Cited by 1,339
Kwok, S., Kellogg, D. E., McKinney, N., Spasic, D., Goda, L., Levenson, C., & Sninsky, J. J. (1990) · Nucleic Acids Research · doi:10.1093/nar/18.4.999 · Cited by 1,046
Ancient DNA: extraction, characterization, molecular cloning, and enzymatic amplification.
Pääbo, S. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.6.1939 · Cited by 1,020
Clark, J. M. (1988) · Nucleic Acids Research · doi:10.1093/nar/16.20.9677 · Cited by 838
Hofreiter, M., Serre, D., Poinar, H. N., Kuch, M., & Pääbo, S. (2001) · Nature Reviews Genetics · doi:10.1038/35072071 · Cited by 781
Self-citationWollaston, W. H. (1810) · Philosophical Transactions of the Royal Society of London · doi:10.1098/rstl.1810.0002 · Cited by 624
Molecular analysis of Neanderthal DNA from the northern Caucasus
Ovchinnikov, I. V., Götherström, A., Romanova, G. P., Kharitonov, V. M., Lidén, K., & Goodwin, W. (2000) · Nature · doi:10.1038/35006625 · Cited by 550
DNA damage promotes jumping between templates during enzymatic amplification.
Pääbo, S., Irwin, D. M., & Wilson, A. C. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)39621-8 · Cited by 498
Research works printed but not linked: 3
- Sambrook,J. and Russel,D.W. (2001) Molecular Cloning: A Laboratory Manual, 3rd Edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
- Krings,M. (1998) Neandertaler DNA-Sequenzen und der Ursprung des modernen Menschen. PhD thesis, Ludwig-Maximilians University, Munich, Germany.
- Mullis,K., Ferre,F. and Gibbs,R. (eds), The Polymerase Chain Reaction. Birkhäuser, Boston, MA, pp. 257-264.
Cited by
Sorted by citations
Items 501–600 of 685
Xu, S., Tran, K. V., Neupane, S., Snyman, M., Huynh, T. V., & Sung, W. (2017) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2017.1548 · Cited by 5
DNA metabarcoding data analysis
Taberlet, P., Bonin, A., Zinger, L., & Coissac, É. (2018) · Oxford University Press eBooks · doi:10.1093/oso/9780198767220.003.0008 · Cited by 6
Abdelmanova, A. S. (2019) · Sel skokhozyaistvennaya Biologiya · doi:10.15389/agrobiology.2019.6.1110eng · Cited by 5
Visualization of Distinct DNA Regions of the Modern Human Relatively to a Neanderthal Genome
Pratas, D., Hosseini, M., Silva, R. M., Pinho, A. J., & Ferreira, P. J. S. G. (2017) · Lecture notes in computer science · doi:10.1007/978-3-319-58838-4_26 · Cited by 4
Agostini, V., Bailo, P., Chiti, E., Linarello, P., Gentile, G., Primignani, P., Giriodi, M., & Piccinini, A. (2019) · Forensic Science International Genetics · doi:10.1016/j.fsigen.2019.102206 · Cited by 5
From genes to genomes: what is new in ancient DNA?
Krause, J. (2010) · Max Planck Digital Library · Cited by 5
ABO genotyping by PCR-RFLP and cloning and sequencing
Haak, W., Bürger, J., & Alt, K. W. (2004) · Anthropologischer Anzeiger · doi:10.1127/anthranz/62/2004/397 · Cited by 5
Chelomina, G. N. (2006) · Russian Journal of Genetics · doi:10.1134/s102279540603001x · Cited by 6
Ancient DNA : Recovery and Analysis
Hummel, S. (2008) · Wiley eBooks · doi:10.1002/9780470015902.a0005342.pub2 · Cited by 5
Mitochondrial DNA analysis of the evolution and genetic diversity of ancient and extinct bears.
Bray, S. C. E. (2011) · Adelaide Research & Scholarship (AR&S) (University of Adelaide) · Cited by 5
Hoelzel, A. R. (2005) · Genome biology · doi:10.1186/gb-2005-6-12-239 · Cited by 5
Organisation génétique des populations d'esturgeon européen Acipenser sturio : passé, présent, futur
Chassaing, O. (2010) · theses.fr (ABES) · doi:10.70675/2212b624z1a62z4646za085zddbbf2fb57ef · Cited by 5
Optimizing ancient DNA recovery from archaeological plant seeds
Bolognesi, G., Latorre, A., Marini, M., Codato, A., Fontani, F., Saggioro, F., Luiselli, D., Basso, P., Cilli, E., & Bellin, D. (2025) · Scientific Reports · doi:10.1038/s41598-025-21743-7 · Cited by 4
Patterns of aDNA damage through time and environments—lessons from herbarium specimens
Porrelli, S., Fornasiero, A., Le, H. P., Yin, W., Rodríguez, M. E. N., Mohammed, N., Himmelbach, A., Clarke, A. C., Stein, N., Kersey, P. J., et al. (2026) · GigaScience · doi:10.1093/gigascience/giag026 · Cited by 4
Human ancient DNA analysis in Latin America: Current state and challenges
Castro, C. D. L. F., & Figueiro, G. (2024) · Archaeometry · doi:10.1111/arcm.12979 · Cited by 7
Rehman, H. U., Arooj, A., Aslam, M. A., Cholistani, M. S., Farhan, M., Kareem, K., Ashraf, M., & Pervaiz, M. A. (2025) · Forensic Science International · doi:10.1016/j.forsciint.2025.112382 · Cited by 6
Bodiba, M. K., Steyn, M., Bloomer, P., Mosothwane, M. N., Rühli, F. J., & Bouwman, A. (2019) · Journal of African Archaeology · doi:10.1163/21915784-20190017 · Cited by 4
Ancient DNA – Pitfalls and Prospects
Gupta, S., Mandal, A., Das, D., & Datta, A. K. (2015) · Indian Journal of Science and Technology · doi:10.17485/ijst/2015/v8i13/60073 · Cited by 4
Multiplex PCR Amplification of Ancient DNA
Stiller, M., & Fulton, T. L. (2011) · Methods in molecular biology · doi:10.1007/978-1-61779-516-9_17 · Cited by 4
Exploring Fennoscandian agricultural history through genetic analysis of aged crop materials
Lundström, M. (2018) · Linköping studies in science and technology. Dissertations · doi:10.3384/diss.diva-152569 · Cited by 4
Ongoing tissue changes in an experimentally mummified human leg
Морозова, И., Öhrström, L. M., Eppenberger, P., Bode‐Lesniewska, B., Gascho, D., Haas, C., Akgül, G., Neukamm, J., Röthlin, K., Imhof, A., et al. (2019) · The Anatomical Record · doi:10.1002/ar.24333 · Cited by 4
Mazanec, J., Hummel, S., & Saile, T. (2020) · Sprawozdania Archeologiczne · doi:10.23858/sa/72.2020.2.1844 · Cited by 4
Taberlet, P., Bonin, A., Zinger, L., & Coissac, É. (2018) · Oxford University Press eBooks · doi:10.1093/oso/9780198767220.003.0017 · Cited by 4
Bannikova, A. A., & Lebedev, V. S. (2022) · Biology Bulletin Reviews · doi:10.1134/s2079086422050024 · Cited by 4
Museomics reveals the phylogenetic position of the extinct Moroccan trout Salmo pallaryi
Delling, B., Thörn, F., Norén, M., & Irestedt, M. (2023) · Journal of Fish Biology · doi:10.1111/jfb.15299 · Cited by 6
Johann, K. S., Bauer, H., Wiegand, P., Pfeiffer, H., & Vennemann, M. (2022) · International Journal of Legal Medicine · doi:10.1007/s00414-022-02911-0 · Cited by 4
Etnogeneza Słowian w świetle badań kopalnego DNA
Juras, A. (2012) · Cited by 4
Ancient DNA and the Genetic Consequences of Late Pleistocene Extinctions
Greenwood, A. D. (2008) · Vertebrate paleobiology and paleoanthroplogy series/Vertebrate paleobiology and paleoanthropology series · doi:10.1007/978-1-4020-8793-6_6 · Cited by 4
Mohandesan, E., Prost, S., & Hofreiter, M. (2011) · Methods in molecular biology · doi:10.1007/978-1-61779-516-9_14 · Cited by 5
Self-citationNext generation sequencing of ancient DNA
Teasdale, M. D. (2013) · Arrow@dit (Dublin Institute of Technology) · Cited by 5
Peyrégne, S., & Peter, B. M. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.03.13.991240 · Cited by 4
de Flamingh, A., Gnoske, T. P., Rivera‐Colón, A. G., Simeonovski, V., Peterhans, J. C. K., Yamaguchi, N., Witt, K. E., Catchen, J., Roca, A. L., & Malhi, R. S. (2023) · Journal of Heredity · doi:10.1093/jhered/esad081 · Cited by 3
Formalin-free tissue embedding is less hazardous and results in better DNA quality
Niemantsverdriet, M., Knol, A., van der Starre-Gaal, J., & Hoogland, A. M. (2024) · PLoS ONE · doi:10.1371/journal.pone.0316107 · Cited by 3
Ancient microbial DNA and proteins preserve in concretions covering human remains
Bonucci, B., de-Dios, T., Barbieri, R., Thompson, J. E., Panella, S., Radina, F., Sivilli, S., Kabral, H., Solnik, A., Tafuri, M. A., et al. (2025) · iScience · doi:10.1016/j.isci.2025.113182 · Cited by 4
Foraminiferal environmental DNA reveals late Holocene sea-level changes
Liu, Z., Khan, N. S., Yu, H. K. Y., Chung, A., Schweizer, M., & Schunter, C. (2025) · Communications Earth & Environment · doi:10.1038/s43247-025-03001-w · Cited by 2
A Mountain Hare Mummy from the Zillertaler Alps
Döppes, D., Gill‐Frerking, H., Joger, U., Rosendahl, W., & Stümpel, N. (2014) · Cited by 3
Butler, J. M. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-374513-2.00010-5 · Cited by 3
Krzewińska, M., Varela, R., Arcini, C., Ahlström, T., Hertzman, N., Storå, J., & Götherström, A. (2021) · Journal of Archaeological Science Reports · doi:10.1016/j.jasrep.2021.102939 · Cited by 3
The Intersection of Forensic Techniques with Ecological Issues
Moore, T., Gaynus, C. J., Levin, P. S., & Meyer, R. S. (2021) · Springer eBooks · doi:10.1007/978-3-030-64682-0_7 · Cited by 3
Mitochondrial DNA and its use in the forensic analysis of skeletal material
Letts, B. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-815766-4.00010-8 · Cited by 3
Liu, Y., Deng, J., Jia, X., Zhou, J., Li, H., Wang, X., Chen, Y., Qin, Z., Jin, Z., & Wang, G. (2023) · New Journal of Chemistry · doi:10.1039/d3nj05083a · Cited by 3
Application of NGS in maternal genome analysis in ancient human remains
Irfan, M., Khan, K., & Khan, N. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-99144-5.00005-6 · Cited by 3
Compacted hair in broken teeth reveals dietary prey of historic lions
de Flamingh, A., Gnoske, T. P., Peterhans, J. C. K., Simeonovski, V., Gitahi, N., Mwebi, O., Agwanda, B. R., Catchen, J., Roca, A. L., & Malhi, R. S. (2024) · Current Biology · doi:10.1016/j.cub.2024.09.029 · Cited by 3
Kishida, T., Sawada, K., Namigata, S., Takabatake, T., Suzuki, M., Takezoe, N., Yamamoto, T., Nakanishi, T., & Kitagawa, H. (2025) · Biology Letters · doi:10.1098/rsbl.2024.0525 · Cited by 3
Binladen, J., & Willerslev, E. (2010) · Journal of Nordic Archaeological Science – JONAS · doi:10.65612/jonas.v17i.63697 · Cited by 3
赖, 旭., 宋, 凌., 袁, 俊., 盛, 桂., & 侯, 新. (2016) · SCIENTIA SINICA Terrae · doi:10.1360/n072015-00539 · Cited by 2
DNA metabarcode choice and design
Taberlet, P., Bonin, A., Zinger, L., & Coissac, É. (2018) · Oxford University Press eBooks · doi:10.1093/oso/9780198767220.003.0002 · Cited by 4
Pusch, C. M., Kayademir, T., Prangenberg, K., Conard, N. J., Czarnetzki, A., & Blin, N. (2002) · PubMed · Cited by 3
Hofreiter, M. (2014) · Oxford University Press eBooks · doi:10.1093/obo/9780199941728-0036 · Cited by 3
Self-citationKrzewińska, M., Varela, R., Yaka, R., Vicente, M., Runfeldt, G., Sager, M., Arcini, C., Ahlström, T., Hertzman, N., Storå, J., et al. (2024) · Heritage · doi:10.3390/heritage7020027 · Cited by 2
AdDeam : a fast and scalable tool for estimating and clustering reference-level damage profiles
Kraft, L., Korneliussen, T. S., Sackett, P. W., & Renaud, G. (2025) · Bioinformatics · doi:10.1093/bioinformatics/btaf407 · Cited by 2
Maróti, Z., Nyerki, E., Neparáczki, E., Tőrők, T., Varga, G. I. B., & Kalmár, T. (2026) · Scientific Reports · doi:10.1038/s41598-026-38372-3 · Cited by 3
Mitochondrial DNA haplotypes of Devensian hyaenas from Creswell Crags, England
Dodge, D. R., Bouwman, A., Pettitt, P., & Brown, T. A. (2012) · Archaeological and Anthropological Sciences · doi:10.1007/s12520-012-0096-1 · Cited by 2
Taberlet, P., Bonin, A., Zinger, L., & Coissac, É. (2018) · Oxford University Press eBooks · doi:10.1093/oso/9780198767220.003.0018 · Cited by 2
Taberlet, P., Bonin, A., Zinger, L., & Coissac, É. (2018) · Oxford University Press eBooks · doi:10.1093/oso/9780198767220.003.0003 · Cited by 2
Wright, S., & Știrbu, F.-C. (2023) · Revista CICSA online Serie Nouă · doi:10.31178/cicsa.2023.9.2 · Cited by 1
Ancient DNA: Results and prospects (The 30th anniversary)
Druzhkova, A. S., Vorobieva, N. V., Trifonov, V. A., & Graphodatsky, A. S. (2015) · Russian Journal of Genetics · doi:10.1134/s1022795415060046 · Cited by 3
An Excess of G over C Nucleotides in Mutagenesis of Human Genetic Diseases
Li, X., Sun, W., Zhang, J., Zhou, Y., Chen, L., Gao, H., Sirois, P., & Li, K. (2010) · Molecular Biotechnology · doi:10.1007/s12033-010-9341-y · Cited by 2
Oben, B., Cosemans, C., Arijs, I., Linsen, L., Daniëls, A., Declercq, J., Maes, B., Vanhees, K., Froyen, G., & Rummens, J. (2018) · Biopreservation and Biobanking · doi:10.1089/bio.2018.0062 · Cited by 2
Takahashi, R., Gushiken, R., Nagata, K., Shinzato, A., Kantha, S. S., & Yasuda, M. (2019) · Mammal Study · doi:10.3106/ms2018-0046 · Cited by 2
Taberlet, P., Bonin, A., Zinger, L., & Coissac, É. (2018) · Oxford University Press eBooks · doi:10.1093/oso/9780198767220.003.0007 · Cited by 2
Elucidating recent history by tracing genetic affinity of three 16th century miners from Sweden
Krzewińska, M., Kjellström, A., Bäckström, Y., Ingvarsson, A., Kashuba, N., Varela, R., Girdland-Flink, L., & Götherström, A. (2018) · Journal of Archaeological Science Reports · doi:10.1016/j.jasrep.2018.03.035 · Cited by 2
Эрнста, Ф. Ф. Ж. —. В. И. А. Л. К., & АБДЕЛЬМАНОВА, А. С. (2019) · Sel skokhozyaistvennaya Biologiya · doi:10.15389/agrobiology.2019.6.1110rus · Cited by 3
Rare versus Artifactual EGFR Mutations
Domingues, P. M., Montella, T. C., & Baldotto, C. S. D. R. (2015) · Journal of Thoracic Oncology · doi:10.1097/jto.0000000000000590 · Cited by 2
Our «Shagreen leather» is our problem. We have to solve it ourselves. 5. Forerunner
Kordyum, V. A. (2005) · Biopolymers and Cell · doi:10.7124/bc.0006ed · Cited by 2
Seifert, L., Harbeck, M., Thomas, A., Hoke, N., Zöller, L., Wiechmann, I., Grupe, G., Scholz, H. C., & Riehm, J. M. (2013) · PLoS ONE · doi:10.1371/annotation/190eceb9-03c6-4d5f-b861-83d44f2a0e53 · Cited by 2
Inconsistencies in Neanderthal genomic DNA sequences
Wall, J. D., & Kim, S. K. (2005) · PLoS Genetics · doi:10.1371/journal.pgen.0030175.eor · Cited by 2
Mammoth and Woolly Rhinoceros, Metagenomics of
Ravin, N. V., Prokhortchouk, E., & Георгиевич, С. К. (2015) · Springer eBooks · doi:10.1007/978-1-4899-7475-4_744 · Cited by 2
Ottoni, C. (2008) · Cineca Institutional Research Information System (Tor Vergata University) · doi:10.58015/ottoni-claudio_phd2008-09-30 · Cited by 2
Taberlet, P., Bonin, A., Zinger, L., & Coissac, É. (2018) · Oxford University Press eBooks · doi:10.1093/oso/9780198767220.003.0013 · Cited by 1
Humpback whale genomes reflect the increased efficiency of commercial whaling
Furni, F., Bérubé, M., Suárez-Menéndez, M., Secchi, E. R., Reeves, R. R., Robbins, J., Speller, C., & Palsbøll, P. J. (2025) · Science Advances · doi:10.1126/sciadv.ady7091 · Cited by 2
Ancient genomes uncover dynamic cultural and genetic interplay in the eastern Tianshan
Yang, X., Zou, X., Li, H., Yang, X., Wang, B., Ma, H., Wang, Y., Xu, Y., Li, C., & Wang, C.-C. (2026) · Molecular Biology and Evolution · doi:10.1093/molbev/msag057 · Cited by 1
Badell, I., Hewett, L., Stotesbury, T. E., Forbes, S. L., & Shafer, A. B. A. (2026) · Journal of Forensic Sciences · doi:10.1111/1556-4029.70304 · Cited by 2
Silverstein, J., & Amber, C. (2026) · Journal of Genetic Engineering and Biotechnology · doi:10.1016/j.jgeb.2026.100702 · Cited by 1
Hebsgaard, M. B., & Willerslev, E. (2008) · Soil biology · doi:10.1007/978-3-540-69371-0_4 · Cited by 1
PrP Gene Polymorphism in Medieval Remains of Sicilian Sheep
Reale, S., Cosenza, M., Sìneo, L., Arcoleo, L., Zaffora, G., Macrì, D., & Vitale, F. (2015) · Open Journal of Animal Sciences · doi:10.4236/ojas.2015.54050 · Cited by 1
Estimating the evidence of selection and the reliability of inference in unigenic evolution
Fernandes, A. D., Kleinstiver, B. P., Edgell, D. R., Wahl, L. M., & Gloor, G. B. (2010) · Algorithms for Molecular Biology · doi:10.1186/1748-7188-5-35 · Cited by 1
Species identification of Collembola by means of PCR-based marker systems
Burkhardt, U. (2005) · State and University Library Bremen · Cited by 1
Pluta, D., Janiszewska, E., Bonar, M., Alama, A., & Dobosz, T. (2018) · Opuscula Musealia · doi:10.4467/20843852.om.17.008.9605 · Cited by 1
Using loop-primer mediated PCR to enhance the detection of poorly preserved DNA
Xiang, H., Wang, Z., Yang, L., Zhang, X., & Zhao, X. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.1000123 · Cited by 1
DNA primer design for sex identification of Sumatran tiger body samples
ASRORI, I., Tjong, D. H., Novarino, W., Mansyurdin, M., Syaifullah, S., & Roesma, D. I. (2023) · Biodiversitas Journal of Biological Diversity · doi:10.13057/biodiv/d240129 · Cited by 1
Kadıkalesi Geç Bizans Dönemi Gömülerinin Mitokondriyel Kökenleri
Tepgeç, F., & Görgülü, M. (2022) · Acta Medica Nicomedia · doi:10.53446/actamednicomedia.1123713 · Cited by 1
Genetic epidemiology of late blight in Australia using ancient DNA
Caruana, B. M., de Boer, R. F., Rodoni, B., Cogan, N. O. I., & Edwards, J. (2023) · Australasian Plant Pathology · doi:10.1007/s13313-023-00936-6 · Cited by 1
Transition of capillary electrophoresis to next generation sequencing for forensic DNA analysis
Al-Snan, N. R. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-99144-5.00023-8 · Cited by 1
Paleogenetic analysis in archeological studies
Сергеевич, П. А., & Молодин, В. И. (2011) · Russian Journal of Genetics Applied Research · doi:10.1134/s2079059711010047 · Cited by 1
Taberlet, P., Bonin, A., Zinger, L., & Coissac, É. (2018) · Oxford University Press eBooks · doi:10.1093/oso/9780198767220.003.0009 · Cited by 1
Panda, M., Sharma, A. N., Shrivastava, P., & Dash, H. R. (2020) · Springer eBooks · doi:10.1007/978-981-15-6655-4_9 · Cited by 1
Taberlet, P., Bonin, A., Zinger, L., & Coissac, É. (2018) · Oxford University Press eBooks · doi:10.1093/oso/9780198767220.003.0015 · Cited by 1
Cave Bear Genomics in the Paleolithic Painted Cave of Chauvet-Pont d’Arc
Bon, C., & Elalouf, J. (2010) · Springer eBooks · doi:10.1007/978-3-642-12340-5_21 · Cited by 1
Polymerase chain reaction: A blessing and a curse for ancient deoxyribonucleic acid research
Hofreiter, M., & Römpler, H. (2009) · Cambridge University Press eBooks · doi:10.1017/cbo9780511818974.021 · Cited by 1
Self-citationEnterobius vermicularis ancient DNA In Pre-Columbian Human Populations
Iñiguez, A. M., Reinhard, K. J., Ferreira, L. F., de Araújo, A. J. G., Carolina, A., & Vincente, P. (2008) · Lincoln (University of Nebraska) · Cited by 1
Reconstructing the Human Past using Ancient and Modern Genomes
Skoglund, P. (2013) · Uppsala University Publications (Uppsala University) · Cited by 1
Genetic Analyses of Bovid Remains and the Origin of Early European Cattle
Anderung, C. (2006) · KTH Publication Database DiVA (KTH Royal Institute of Technology) · Cited by 1
Paleogenomics Using the 454 Sequencing Platform
Gilbert, M. T. P. (2008) · Wiley eBooks · doi:10.1002/9783527625130.ch14 · Cited by 1
An evaluation of forensic DNA profiling techniques currently used in the United Kingdom
Graham, E. A. M. (2007) · Leicester Research Archive (University of Leicester) · Cited by 1
Advances in ancient DNA studies
Caramelli, D., & Lago, G. (2006) · Florence Research (University of Florence) · Cited by 1
Renneberg, R. (2008) · doi:10.53846/goediss-262 · Cited by 1
Mammoth and Woolly Rhinoceros, Metagenomics of
Ravin, N. V., Prokhortchouk, E., & Георгиевич, С. К. (2013) · Springer eBooks · doi:10.1007/978-1-4614-6418-1_744-3 · Cited by 1
An assessment of the impact of environmental factors on the quality of post-mortem DNA profiling.
Gunawardane, D. M. D. D. N. (2009) · Adelaide Research & Scholarship (AR&S) (University of Adelaide) · Cited by 1
Metadata
- Authors
- Hofreiter, M.
- Affiliations
- Max Planck Institute for Evolutionary Anthropology (DE)
- Corresponding author
- Hofreiter, M.
- ORCID
- Hofreiter, M.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2001-12-01
- Volume
- 29
- Issue
- 23
- Pages
- 4793-4799
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- PMC
- PMC96698
- OpenAlex
- W2013367562
- Cited by
- 684
- References
- 29
- Citations by year
- 2026: 13 · 2025: 17 · 2024: 14 · 2023: 24 · 2022: 24 · 2021: 23 · 2020: 37 · 2019: 27 · 2018: 52 · 2017: 26 · 2016: 26 · 2015: 28 · 2014: 37 · 2013: 31 · 2012: 27
- FWCI
- 7.30
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Nucleic Acids Research (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Max Planck Institute for Plasma Physics (submittedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion, other-oa)
- Funders
- Deutsche Forschungsgemeinschaft
- Max-Planck-Gesellschaft
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Forensic and Genetic Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Molecular Biology Techniques and Applications
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
- Keywords
- ancient DNA, cytosine deamination, PCR artifacts, uracil-DNA glycosylase, template switching, sequencing error rate
- MeSH terms
- Animals, Base Sequence, Bone and Bones, Cloning, Molecular, Cytosine, Deamination, DNA, Models, Genetic, Molecular Sequence Data, N-Glycosyl Hydrolases, Paleontology, Polymerase Chain Reaction, Mutagenesis, Artifacts, Sequence Analysis, DNA, DNA Glycosylases, History, Ancient, Uracil-DNA Glycosidase
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
