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Cited by 202

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Oligonucleotide directed mutagenesis of the human β-globin gene: a general method for producing specific point mutations in cloned DNA

Open access
Bruce Wallace, R., Schold, Monica, Johnson, Merrie Jo, Dembek, Piotr, Itakura, Keiichi·1981·Nucleic Acids Research

Abstract

A nonadecanucleotide has been used both as a site specific mutagen to introduce a T leads to A transversion mutation in the human beta-globin gene cloned in pBR322 as well as a probe to screen transformed colonies for the desired mutant. The specificity of the oligonucleotide as a mutagen and as a hybridization probe provide a general method for producing site specific mutations in DNA cloned in plasmid vectors such as pBR322.

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Crossref · 10.1093/nar/9.15.3647

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Metadata

Authors
Bruce Wallace, R., Schold, M., Johnson, M. J., Dembek, P., & Itakura, K.
Venue
Nucleic Acids Research
Published
1981
Volume
9
Issue
15
Pages
3647-3656
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W1969671032
Cited by
202
References
1
FWCI
22.14
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Oligonucleotide directed mutagenesis of the human β-globin gene: a general method for producing specific point mutations in cloned DNA. https://app.cochat.ai/papers/10.1093/nar/9.15.3647
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Bruce Wallace, R., Schold, M., Johnson, M. J., Dembek, P., & Itakura, K. (1981). Oligonucleotide directed mutagenesis of the human β-globin gene: a general method for producing specific point mutations in cloned DNA. Nucleic Acids Research. https://doi.org/10.1093/nar/9.15.3647

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