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The Mouse Genome Database (MGD): from genes to mice--a community resource for mouse biology
Open accessAbstract
The Mouse Genome Database (MGD) forms the core of the Mouse Genome Informatics (MGI) system (http://www.informatics.jax.org), a model organism database resource for the laboratory mouse. MGD provides essential integration of experimental knowledge for the mouse system with information annotated from both literature and online sources. MGD curates and presents consensus and experimental data representations of genotype (sequence) through phenotype information, including highly detailed reports about genes and gene products. Primary foci of integration are through representations of relationships among genes, sequences and phenotypes. MGD collaborates with other bioinformatics groups to curate a definitive set of information about the laboratory mouse and to build and implement the data and semantic standards that are essential for comparative genome analysis. Recent improvements in MGD discussed here include the enhancement of phenotype resources, the re-development of the International Mouse Strain Resource, IMSR, the update of mammalian orthology datasets and the electronic publication of classic books in mouse genetics.
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Cited by
Bogan, K. L., & Brenner, C. (2008) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.28.061807.155443 · Cited by 707
Mechanisms of ectodermal organogenesis.
Pispa, J., & Thesleff, I. (2003) · Developmental Biology · doi:10.1016/s0012-1606(03)00325-7 · Cited by 499
Weighted gene coexpression network analysis strategies applied to mouse weight
Fuller, T. F., Ghazalpour, A., Aten, J. E., Drake, T. A., Lusis, A. J., & Horvath, S. (2007) · Mammalian Genome · doi:10.1007/s00335-007-9043-3 · Cited by 373
Lee, I., Lehner, B., Crombie, C., Wong, W., Fraser, A. G., & Marcotte, E. M. (2008) · Nature Genetics · doi:10.1038/ng.2007.70 · Cited by 281
The mouse as a model for human biology: a resource guide for complex trait analysis
Peters, L. L., Robledo, R. F., Bult, C. J., Churchill, G. A., Paigen, B. J., & Svenson, K. L. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2025 · Cited by 287
Metadata
- Authors
- Eppig, J. T.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2004-12-17
- Volume
- 33
- Issue
- Database issue
- Pages
- D471-D475
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W2104878392
- Cited by
- 277
- References
- 0
- FWCI
- 12.25
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Eppig, J. T. (2004). The Mouse Genome Database (MGD): from genes to mice--a community resource for mouse biology. Nucleic Acids Research. https://doi.org/10.1093/nar/gki113
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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
