The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
TOPCONS: consensus prediction of membrane protein topology
Open accessAbstract
TOPCONS (http://topcons.net/) is a web server for consensus prediction of membrane protein topology. The underlying algorithm combines an arbitrary number of topology predictions into one consensus prediction and quantifies the reliability of the prediction based on the level of agreement between the underlying methods, both on the protein level and on the level of individual TM regions. Benchmarking the method shows that overall performance levels match the best available topology prediction methods, and for sequences with high reliability scores, performance is increased by approximately 10 percentage points. The web interface allows for constraining parts of the sequence to a known inside/outside location, and detailed results are displayed both graphically and in text format.
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Cites
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Li, W., & Godzik, A. (2006) · Bioinformatics · doi:10.1093/bioinformatics/btl158 · Cited by 11,410
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The HMMTOP transmembrane topology prediction server
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Self-citationImproving the accuracy of transmembrane protein topology prediction using evolutionary information
Jones, D. T. (2007) · Bioinformatics · doi:10.1093/bioinformatics/btl677 · Cited by 419
Viklund, H., & Elofsson, A. (2008) · Bioinformatics · doi:10.1093/bioinformatics/btn221 · Cited by 382
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The TOPCONS web server for consensus prediction of membrane protein topology and signal peptides
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Metadata
- Authors
- Bernsel, A., Viklund, H., Hennerdal, A., & Elofsson, A.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-05-08
- Volume
- 37
- Issue
- Web Server
- Pages
- W465-W468
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W2092247420
- Cited by
- 537
- References
- 15
- FWCI
- 12.84
- Type
- journal article
- Language
- en
- Open access
- gold
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